Ion channels are the dynamical systems of the nervous system. Their distribution within the membrane governs not only communication of information between neurons, but also how that information is integrated within the cell. Here, an argument is presented for an'anti-Hebbian' rule for changing the distribution of voltage-dependent ion channels in order to flatten voltage curvatures in dendrites. Simulations show that this rule can account for the self-organisation of dynamical receptive field properties such as resonance and direction selectivity. It also creates the conditions for the faithful conduction within the cell of signals to which the cell has been exposed. Various possible cellular implementations of such a learning rule are proposed, including activity-dependent migration of channel proteins in the plane of the membrane.

I exhibit a systematic way to derive neural nets for vision problems.

We present an iterative algorithm for nonlinear regression based on construction of sparse polynomials. Polynomials are built sequentially from lower to higher order. Selection of new terms is accomplished using a novel look-ahead approach that predicts whether a variable contributes to the remaining error. The algorithm is based on the tree-growing heuristic in LMS Trees which we have extended to approximation of arbitrary polynomials of the input features. In addition, we provide a new theoretical justification for this heuristic approach.

Visual attention is the ability to dynamically restrict processing to a subset of the visual field. Researchers have long argued that such a mechanism is necessary to efficiently perform many intermediate level visual tasks. This paper describes VISIT, a novel neural network model of visual attention.

Analog hardware has obvious advantages in terms of its size, speed, cost, and power consumption. Analog chip designers, however, should not feel constrained to mapping existing digital algorithms to silicon. Many times, new algorithms must be adapted or invented to ensure efficient implementation in analog hardware. Novel analog algorithms embedded in the hardware must be simple and obey the natural constraints of physics. Much algorithm intuition can be gained from experimenting with these continuous-time nonlinear systems. For example, the algorithm described in this paper arose from experimentation with existing analog segmentation hardware. Surprisingly, many of these "analog" algorithms may prove useful even if a computer vision researcher is limited to simulating the analog hardware on a digital computer [7].

A method for transforming performance evaluation signals distal both in space and time into proximal signals usable by supervised learning algorithms, presented in [Jordan & Jacobs 90], is examined. A simple observation concerning differentiation through models trained with redundant inputs (as one of their networks is) explains a weakness in the original architecture and suggests a modification: an internal world model that encodes action-space exploration and, crucially, cancels input redundancy to the forward model is added. Learning time on an example task, cartpole balancing, is thereby reduced about 50 to 100 times. 1 INTRODUCTION In many learning control problems, the evaluation used to modify (and thus improve) control may not be available in terms of the controller's output: instead, it may be in terms of a spatial transformation of the controller's output variables (in which case we shall term it as being "distal in space"), or it may be available only several time steps into the future (termed as being "distal in time"). For example, control of a robot arm may be exerted in terms of joint angles, while evaluation may be in terms of the endpoint cartesian coordinates; furthermore, we may only wish to evaluate the endpoint coordinates reached after a certain period of time: the co- ·Current address: Computation and Neural Systems Program, California Institute of Technology, Pasadena CA.

An alternative to the typical technique of selecting training examples independently from a fixed distribution is fonnulated and analyzed, in which the current example is presented repeatedly until the error for that item is reduced to some criterion value,; then, another item is randomly selected. The convergence time can be dramatically increased or decreased by this heuristic, depending on the task, and is very sensitive to the value of .

Although many workers have applied neural nets to various types of I-dimensional medical data (e.g. ECG and EEG waveforms), little work has been done on applying neural nets to diagnosis directly from medical images.

We propose a paradigm for modeling speech production based on neural networks. We focus on characteristics of the musculoskeletal system. Using real physiological data - articulator movements and EMG from muscle activitya neural network learns the forward dynamics relating motor commands to muscles and the ensuing articulator behavior. After learning, simulated perturbations, were used to asses properties of the acquired model, such as natural frequency, damping, and interarticulator couplings. Finally, a cascade neural network is used to generate continuous motor commands from a sequence of discrete articulatory targets.

We propose and empirically evaluate a method for the extraction of expertcomprehensible rules from trained neural networks. Our method operates in the context of a three-step process for learning that uses rule-based domain knowledge in combination with neural networks. Empirical tests using realworlds problems from molecular biology show that the rules our method extracts from trained neural networks: closely reproduce the accuracy of the network from which they came, are superior to the rules derived by a learning system that directly refines symbolic rules, and are expert-comprehensible.