Granger Causality: A Review and Recent Advances

There is a range of applications where the interest is in understanding interactions between a set of time series, including in neuroscience, genomics, econometrics, climate science, and social media analysis. For example, in neuroscience, one may seek to understand whether activity in one brain region correlates with later activity in another region, or to decipher instantaneous correlations between regions--both notions of functional connectivity. In genomics, there is an analogous study of gene regulatory networks. In econometrics, one may be interested in how various macroeconomic indicators predict one another. We also have unprecedented levels of data on people's actions--whether they be social media posts, purchase histories, or political voting records--and want to understand the dependencies between the actions of these individuals. Modern recording modalities and the ability to store and process large amounts of data have escalated the scale at which we seek to do such analyses. In many cases, one may seek notions of causal interactions amongst the time series, but be limited to drawing inferences from observational data without opportunities for experimentation and without known mechanistic models for the observed phenomena.