Inference for BART with Multinomial Outcomes
Xu, Yizhen, Hogan, Joseph W., Daniels, Michael J., Kantor, Rami, Mwangi, Ann
The multinomial probit Bayesian additive regression trees (MPBART) framework was proposed by Kindo et al. (KD), approximating the latent utilities in the multinomial probit (MNP) model with BART (Chipman et al. 2010). Compared to multinomial logistic models, MNP does not assume independent alternatives and the correlation structure among alternatives can be specified through multivariate Gaussian distributed latent utilities. We introduce two new algorithms for fitting the MPBART and show that the theoretical mixing rates of our proposals are equal or superior to the existing algorithm in KD. Through simulations, we explore the robustness of the methods to the choice of reference level, imbalance in outcome frequencies, and the specifications of prior hyperparameters for the utility error term. The work is motivated by the application of generating posterior predictive distributions for mortality and engagement in care among HIV-positive patients based on electronic health records (EHRs) from the Academic Model Providing Access to Healthcare (AMPATH) in Kenya. In both the application and simulations, we observe better performance using our proposals as compared to KD in terms of MCMC convergence rate and posterior predictive accuracy.
Jan-17-2021
- Country:
- Africa > Kenya
- Uasin Gishu County > Eldoret (0.04)
- North America > United States
- Florida > Alachua County
- Gainesville (0.14)
- Maryland > Baltimore (0.04)
- North Carolina (0.04)
- Rhode Island > Providence County
- Providence (0.04)
- Florida > Alachua County
- Africa > Kenya
- Genre:
- Research Report (0.50)
- Industry:
- Health & Medicine > Therapeutic Area
- Immunology > HIV (0.68)
- Infections and Infectious Diseases (1.00)
- Health & Medicine > Therapeutic Area