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Diagnosing Hallucination Risk in AI Surgical Decision-Support: A Sequential Framework for Sequential Validation
Chen, Dong, Wei, Yanzhe, He, Zonglin, Kuang, Guan-Ming, Ye, Canhua, An, Meiru, Peng, Huili, Hu, Yong, Tao, Huiren, Cheung, Kenneth MC
Large language models (LLMs) offer transformative potential for clinical decision support in spine surgery but pose significant risks through hallucinations, which are factually inconsistent or contextually misaligned outputs that may compromise patient safety. This study introduces a clinician-centered framework to quantify hallucination risks by evaluating diagnostic precision, recommendation quality, reasoning robustness, output coherence, and knowledge alignment. We assessed six leading LLMs across 30 expert-validated spinal cases. DeepSeek-R1 demonstrated superior overall performance (total score: 86.03 $\pm$ 2.08), particularly in high-stakes domains such as trauma and infection. A critical finding reveals that reasoning-enhanced model variants did not uniformly outperform standard counterparts: Claude-3.7-Sonnet's extended thinking mode underperformed relative to its standard version (80.79 $\pm$ 1.83 vs. 81.56 $\pm$ 1.92), indicating extended chain-of-thought reasoning alone is insufficient for clinical reliability. Multidimensional stress-testing exposed model-specific vulnerabilities, with recommendation quality degrading by 7.4% under amplified complexity. This decline contrasted with marginal improvements in rationality (+2.0%), readability (+1.7%) and diagnosis (+4.7%), highlighting a concerning divergence between perceived coherence and actionable guidance. Our findings advocate integrating interpretability mechanisms (e.g., reasoning chain visualization) into clinical workflows and establish a safety-aware validation framework for surgical LLM deployment.
SPIRAL: Self-Play Incremental Racing Algorithm for Learning in Multi-Drone Competitions
This paper introduces SPIRAL (Self-Play Incremental Racing Algorithm for Learning), a novel approach for training autonomous drones in multi-agent racing competitions. SPIRAL distinctively employs a self-play mechanism to incrementally cultivate complex racing behaviors within a challenging, dynamic environment. Through this self-play core, drones continuously compete against increasingly proficient versions of themselves, naturally escalating the difficulty of competitive interactions. This progressive learning journey guides agents from mastering fundamental flight control to executing sophisticated cooperative multi-drone racing strategies. Our method is designed for versatility, allowing integration with any state-of-the-art Deep Reinforcement Learning (DRL) algorithms within its self-play framework. Simulations demonstrate the significant advantages of SPIRAL and benchmark the performance of various DRL algorithms operating within it. Consequently, we contribute a versatile, scalable, and self-improving learning framework to the field of autonomous drone racing. SPIRAL's capacity to autonomously generate appropriate and escalating challenges through its self-play dynamic offers a promising direction for developing robust and adaptive racing strategies in multi-agent environments. This research opens new avenues for enhancing the performance and reliability of autonomous racing drones in increasingly complex and competitive scenarios.
Multi-dimensional Data Analysis and Applications Basing on LLM Agents and Knowledge Graph Interactions
Wang, Xi, Ling, Xianyao, Li, Kun, Yin, Gang, Zhang, Liang, Wu, Jiang, Xu, Jun, Zhang, Fu, Lei, Wenbo, Wang, Annie, Gong, Peng
In the current era of big data, extracting deep insights from massive, heterogeneous, and complexly associated multi-dimensional data has become a significant challenge. Large Language Models (LLMs) perform well in natural language understanding and generation, but still suffer from "hallucination" issues when processing structured knowledge and are difficult to update in real-time. Although Knowledge Graphs (KGs) can explicitly store structured knowledge, their static nature limits dynamic interaction and analytical capabilities. Therefore, this paper proposes a multi-dimensional data analysis method based on the interactions between LLM agents and KGs, constructing a dynamic, collaborative analytical ecosystem. This method utilizes LLM agents to automatically extract product data from unstructured data, constructs and visualizes the KG in real-time, and supports users in deep exploration and analysis of graph nodes through an interactive platform. Experimental results show that this method has significant advantages in product ecosystem analysis, relationship mining, and user-driven exploratory analysis, providing new ideas and tools for multi-dimensional data analysis.
Multi-Objective $\textit{min-max}$ Online Convex Optimization
In online convex optimization (OCO), a single loss function sequence is revealed over a time horizon of $T$, and an online algorithm has to choose its action at time $t$, before the loss function at time $t$ is revealed. The goal of the online algorithm is to incur minimal penalty (called $\textit{regret}$ compared to a static optimal action made by an optimal offline algorithm knowing all functions of the sequence in advance. In this paper, we broaden the horizon of OCO, and consider multi-objective OCO, where there are $K$ distinct loss function sequences, and an algorithm has to choose its action at time $t$, before the $K$ loss functions at time $t$ are revealed. To capture the tradeoff between tracking the $K$ different sequences, we consider the $\textit{min-max}$ regret, where the benchmark (optimal offline algorithm) takes a static action across all time slots that minimizes the maximum of the total loss (summed across time slots) incurred by each of the $K$ sequences. An online algorithm is allowed to change its action across time slots, and its {\it min-max} regret is defined as the difference between its $\textit{min-max}$ cost and that of the benchmark. The $\textit{min-max}$ regret is a stringent performance measure and an algorithm with small regret needs to `track' all loss function sequences closely at all times. We consider this $\textit{min-max}$ regret in the i.i.d. input setting where all loss functions are i.i.d. generated from an unknown distribution. For the i.i.d. model we propose a simple algorithm that combines the well-known $\textit{Hedge}$ and online gradient descent (OGD) and show via a remarkably simple proof that its expected $\textit{min-max}$ regret is $O(\sqrt{T \log K})$.
Formal Models and Convergence Analysis for Context-Aware Security Verification
Traditional security scanners fail when facing new attack patterns they haven't seen before. They rely on fixed rules and predetermined signatures, making them blind to novel threats. We present a fundamentally different approach: instead of memorizing specific attack patterns, we learn what makes systems genuinely secure. Our key insight is simple yet powerful: context determines vulnerability. A SQL query that's safe in one environment becomes dangerous in another. By modeling this context-vulnerability relationship, we achieve something remarkable: our system detects attacks it has never seen before. We introduce context-aware verification that learns from genuine system behavior. Through reconstruction learning on secure systems, we capture their essential characteristics. When an unknown attack deviates from these patterns, our system recognizes it, even without prior knowledge of that specific attack type. We prove this capability theoretically, showing detection rates improve exponentially with context information I(W;C). Our framework combines three components: (1) reconstruction learning that models secure behavior, (2) multi-scale graph reasoning that aggregates contextual clues, and (3) attention mechanisms guided by reconstruction differences. Extensive experiments validate our approach: detection accuracy jumps from 58 percent to 82 percent with full context, unknown attack detection improves by 31 percent, and our system maintains above 90 percent accuracy even against completely novel attack vectors.
FATHOMS-RAG: A Framework for the Assessment of Thinking and Observation in Multimodal Systems that use Retrieval Augmented Generation
Hildebrand, Samuel, Taylor, Curtis, Oesch, Sean, Ghawaly, James M Jr, Sadovnik, Amir, Shivers, Ryan, Schreiber, Brandon, Kurian, Kevin
Abstract--Retrieval-augmented generation (RAG) has emerged as a promising paradigm for improving factual accuracy in large language models (LLMs). We introduce a benchmark designed to evaluate RAG pipelines as a whole, evaluating a pipeline's ability to ingest, retrieve, and reason about several modalities of information, differentiating it from existing benchmarks that focus on particular aspects such as retrieval. We present (1) a small, human-created dataset of 93 questions designed to evaluate a pipeline's ability to ingest textual data, tables, images, and data spread across these modalities in one or more documents; (2) a phrase-level recall metric for correctness; (3) a nearest-neighbor embedding classifier to identify potential pipeline hallucinations; (4) a comparative evaluation of 2 pipelines built with open-source retrieval mechanisms and 4 closed-source foundation models; and (5) a third-party human evaluation of the alignment of our correctness and hallucination metrics. We find that closed-source pipelines significantly outperform open-source pipelines in both correctness and hallucination metrics, with wider performance gaps in questions relying on multimodal and cross-document information. Human evaluation of our metrics showed average agreement of 4.62 for correctness and 4.53 for hallucination detection on a 1-5 Likert scale (5 indicating "strongly agree"). Research sponsored by the Laboratory Directed Research and Development Program of Oak Ridge National Laboratory, managed by UT -Battelle, LLC, for the U. S. Department of Energy. Notice: This manuscript has been authored by UT -Battelle, LLC under Contract No. DE-AC05-00OR22725 with the U.S. Department of Energy. The United States Government retains and the publisher, by accepting the article for publication, acknowledges that the United States Government retains a non-exclusive, paid-up, irrevocable, world-wide license to publish or reproduce the published form of this manuscript, or allow others to do so, for United States Government purposes.
Practical and Stealthy Touch-Guided Jailbreak Attacks on Deployed Mobile Vision-Language Agents
Ding, Renhua, Yang, Xiao, Fang, Zhengwei, Luo, Jun, He, Kun, Zhu, Jun
Large vision-language models (LVLMs) enable autonomous mobile agents to operate smartphone user interfaces, yet vulnerabilities in their perception and interaction remain critically understudied. Existing research often relies on conspicuous overlays, elevated permissions, or unrealistic threat assumptions, limiting stealth and real-world feasibility. In this paper, we introduce a practical and stealthy jailbreak attack framework, which comprises three key components: (i) non-privileged perception compromise, which injects visual payloads into the application interface without requiring elevated system permissions; (ii) agent-attributable activation, which leverages input attribution signals to distinguish agent from human interactions and limits prompt exposure to transient intervals to preserve stealth from end users; and (iii) efficient one-shot jailbreak, a heuristic iterative deepening search algorithm (HG-IDA*) that performs keyword-level detoxification to bypass built-in safety alignment of LVLMs. Moreover, we developed three representative Android applications and curated a prompt-injection dataset for mobile agents. We evaluated our attack across multiple LVLM backends, including closed-source services and representative open-source models, and observed high planning and execution hijack rates (e.g., GPT-4o: 82.5% planning / 75.0% execution), exposing a fundamental security vulnerability in current mobile agents and underscoring critical implications for autonomous smartphone operation.
Sigma: Semantically Informative Pre-training for Skeleton-based Sign Language Understanding
Pu, Muxin, Lim, Mei Kuan, Chong, Chun Yong, Loy, Chen Change
Pre-training has proven effective for learning transferable features in sign language understanding (SLU) tasks. Recently, skeleton-based methods have gained increasing attention because they can robustly handle variations in subjects and backgrounds without being affected by appearance or environmental factors. Current SLU methods continue to face three key limitations: 1) weak semantic grounding, as models often capture low-level motion patterns from skeletal data but struggle to relate them to linguistic meaning; 2) imbalance between local details and global context, with models either focusing too narrowly on fine-grained cues or overlooking them for broader context; and 3) inefficient cross-modal learning, as constructing semantically aligned representations across modalities remains difficult. To address these, we propose Sigma, a unified skeleton-based SLU framework featuring: 1) a sign-aware early fusion mechanism that facilitates deep interaction between visual and textual modalities, enriching visual features with linguistic context; 2) a hierarchical alignment learning strategy that jointly maximises agreements across different levels of paired features from different modalities, effectively capturing both fine-grained details and high-level semantic relationships; and 3) a unified pre-training framework that combines contrastive learning, text matching and language modelling to promote semantic consistency and generalisation. Sigma achieves new state-of-the-art results on isolated sign language recognition, continuous sign language recognition, and gloss-free sign language translation on multiple benchmarks spanning different sign and spoken languages, demonstrating the impact of semantically informative pre-training and the effectiveness of skeletal data as a stand-alone solution for SLU.
Evaluating Multimodal Large Language Models with Daily Composite Tasks in Home Environments
Zhang, Zhenliang, Wang, Yuxi, Xie, Hongzhao, Zhao, Shiyun, Liu, Mingyuan, Lu, Yujie, He, Xinyi, Cheng, Zhenku, Peng, Yujia
A key feature differentiating artificial general intelligence (AGI) from traditional AI is that AGI can perform composite tasks that require a wide range of capabilities. Although embodied agents powered by multimodal large language models (MLLMs) offer rich perceptual and interactive capabilities, it remains largely unexplored whether they can solve composite tasks. In the current work, we designed a set of composite tasks inspired by common daily activities observed in early childhood development. Within a dynamic and simulated home environment, these tasks span three core domains: object understanding, spatial intelligence, and social activity. We evaluated 17 leading proprietary and open-source MLLMs on these tasks. The results consistently showed poor performance across all three domains, indicating a substantial gap between current capabilities and general intelligence requirements. Together, our tasks offer a preliminary framework for evaluating the general capabilities of embodied agents, marking an early but significant step toward the development of embodied MLLMs and their real-world deployment.
Interpretability as Alignment: Making Internal Understanding a Design Principle
Sengupta, Aadit, Seth, Pratinav, Sankarapu, Vinay Kumar
Frontier AI systems require governance mechanisms that can verify internal alignment, not just behavioral compliance. Private governance mechanisms audits, certification, insurance, and procurement are emerging to complement public regulation, but they require technical substrates that generate verifiable causal evidence about model behavior. This paper argues that mechanistic interpretability provides this substrate. We frame interpretability not as post-hoc explanation but as a design constraint embedding auditability, provenance, and bounded transparency within model architectures. Integrating causal abstraction theory and empirical benchmarks such as MIB and LoBOX, we outline how interpretability-first models can underpin private assurance pipelines and role-calibrated transparency frameworks. This reframing situates interpretability as infrastructure for private AI governance bridging the gap between technical reliability and institutional accountability.