Artificial neural networks revolutionise biological image analysis

Scientists use super-resolution microscopy to study previously undiscovered cellular worlds, revealing nanometre-scale details inside cells. The method revolutionised light microscopy and earned its inventors the 2014 Nobel Prize in Chemistry. Single-molecule localisation microscopy (SMLM) is a type of super-resolution microscopy. It involves labelling proteins of interest with fluorescent molecules and using light to activate only a few molecules at a time. Using this method, multiple images of the same sample are acquired.