Fully Convolutional Networks for Monocular Retinal Depth Estimation and Optic Disc-Cup Segmentation

Shankaranarayana, Sharath M, Ram, Keerthi, Mitra, Kaushik, Sivaprakasam, Mohanasankar

arXiv.org Machine Learning 

Abstract--Glaucoma is a serious ocular disorder for which the screening and diagnosis are carried out by the examination of the optic nerve head (ONH). The color fundus image (CFI) is the most common modality used for ocular screening. In CFI, the central region which is the optic disc and the optic cup region within the disc are examined to determine one of the important cues for glaucoma diagnosis called the optic cup-to-disc ratio (CDR). CDR calculation requires accurate segmentation of optic disc and cup. Another important cue for glaucoma progression is the variation of depth in ONH region. In this work, we first propose a deep learning framework to estimate depth from a single fundus image. For the case of monocular retinal depth estimation, we are also plagued by the labelled data insufficiency. To overcome this problem we adopt the technique of pretraining the deep network where, instead of using a denoising autoencoder, we propose a new pretraining scheme called pseudo-depth reconstruction, which serves as a proxy task for retinal depth estimation. Empirically, we show pseudo-depth reconstruction to be a better proxy task than denoising.

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