Text-to-image diffusion models excel at translating language prompts into photorealistic images by implicitly grounding textual concepts through their cross-modal attention mechanisms. Recent multi-modal diffusion transformers extend this by introducing joint self-attention over concatenated image and text tokens, enabling richer and more scalable cross-modal alignment. However, a detailed understanding of how and where these attention maps contribute to image generation remains limited. In this paper, we introduce Seg4Diff (Segmentation for Diffusion), a systematic framework for analyzing the attention structures of MM-DiT, with a focus on how specific layers propagate semantic information from text to image. Through comprehensive analysis, we identify a semantic grounding expert layer, a specific MM-DiT block that consistently aligns text tokens with spatially coherent image regions, naturally producing high-quality semantic segmentation masks. We further demonstrate that applying a lightweight fine-tuning scheme with mask-annotated image data enhances the semantic grouping capabilities of these layers and thereby improves both segmentation performance and generated image fidelity. Our findings demonstrate that semantic grouping is an emergent property of diffusion transformers and can be selectively amplified to advance both segmentation and generation performance, paving the way for unified models that bridge visual perception and generation.

Activation functions are fundamental elements of deep learning architectures as they significantly influence training dynamics. ReLU, while widely used, is prone to the dying neuron problem, which has been mitigated by variants such as LeakyReLU, PReLU, and ELU that better handle negative neuron outputs. Recently, self-gated activations like GELU and Swish have emerged as state-of-the-art alternatives, leveraging their smoothness to ensure stable gradient flow and prevent neuron inactivity. In this work, we introduce the Gompertz Linear Unit (GoLU), a novel self-gated activation function defined as $\mathrm{GoLU}(x) = x \\, \mathrm{Gompertz}(x)$, where $\mathrm{Gompertz}(x) = e^{-e^{-x}}$. The GoLU activation leverages the right-skewed asymmetry in the Gompertz function to reduce variance in the latent space more effectively compared to GELU and Swish, while preserving robust gradient flow. Extensive experiments across diverse tasks, including Image Classification, Language Modeling, Semantic Segmentation, Object Detection, Instance Segmentation, and Diffusion, highlight GoLU's superior performance relative to state-of-the-art activation functions, establishing GoLU as a robust alternative to existing activation functions.

The whole-slide pathology images (WSIs) are widely recognized as the golden standard for cancer survival analysis. However, due to the high-resolution of WSIs, the existing studies require dividing WSIs into patches and identify key components before building the survival prediction system, which is time-consuming and cannot reflect the overall spatial organization of WSIs. Inspired by the fact that the spatial interactions among different tumor microenvironment (TME) components in WSIs are associated with the cancer prognosis, some studies attempt to capture the complex interactions among different TME components to improve survival predictions. However, they require extra efforts for building the TME segmentation model, which involves substantial annotation workloads on different TME components and is independent to the construction of the survival prediction model. To address the above issues, we propose ZTSurv, a novel end-to-end cancer survival analysis framework via efficient zero-shot TME segmentation on low-resolution WSIs. Specifically, by leveraging tumor infiltrating lymphocyte (TIL) maps on the 50x down-sampled WSIs, ZTSurv enables zero-shot segmentation on other two important TME components (i.e., tumor and stroma) that can reduce the annotation efforts from the pathologists. Then, based on the visual and semantic information extracted from different TME components, we construct a heterogeneous graph to capture their spatial intersections for clinical outcome prediction. We validate ZTSurv across four cancer cohorts derived from The Cancer Genome Atlas (TCGA), and the experimental results indicate that our method can not only achieve superior prediction results but also significantly reduce the computational costs in comparison with the state-of-the-art methods.

Recent advancements in multimodal models have significantly improved vision-language (VL) alignment in radiology. However, existing approaches struggle to effectively utilize complex radiology reports for learning and offer limited interpretability through attention probability visualizations. To address these challenges, we introduce $\textbf{RadZero}$, a novel framework for VL alignment in chest X-ray with zero-shot multi-task capability.

Video camouflaged object segmentation (VCOS), aiming at segmenting camouflaged objects that seamlessly blend into their environment, is a fundamental vision task with various real-world applications. With the release of SAM2, video segmentation has witnessed significant progress. However, SAM2's capability of segmenting camouflaged videos is suboptimal, especially when given simple prompts such as point and box. To address the problem, we propose Camouflaged SAM2 (CamSAM2), which enhances SAM2's ability to handle camouflaged scenes without modifying SAM2's parameters. Specifically, we introduce a decamouflaged token to provide the flexibility of feature adjustment for VCOS. To make full use of fine-grained and high-resolution features from the current frame and previous frames, we propose implicit object-aware fusion (IOF) and explicit object-aware fusion (EOF) modules, respectively. Object prototype generation (OPG) is introduced to abstract and memorize object prototypes with informative details using high-quality features from previous frames. Extensive experiments are conducted to validate the effectiveness of our approach. While CamSAM2 only adds negligible learnable parameters to SAM2, it substantially outperforms SAM2 on three VCOS datasets, especially achieving 12.2 mDice gains with click prompt on MoCA-Mask and 19.6 mDice gains with mask prompt on SUN-SEG-Hard, with Hiera-T as the backbone.

Online, real-time, and fine-grained 3D segmentation constitutes a fundamental capability for embodied intelligent agents to perceive and comprehend their operational environments. Recent advancements employ predefined object queries to aggregate semantic information from Vision Foundation Models (VFMs) outputs that are lifted into 3D point clouds, facilitating spatial information propagation through inter-query interactions. Nevertheless, perception, whether human or robotic, is an inherently dynamic process, rendering temporal understanding a critical yet overlooked dimension within these prevailing query-based pipelines. This deficiency in temporal reasoning can exacerbate issues such as the over-segmentation commonly produced by VFMs, necessitating more handcrafted post-processing. Therefore, to further unlock the temporal environmental perception capabilities of embodied agents, our work reconceptualizes online 3D segmentation as an instance tracking problem (AutoSeg3D).

Long-horizon video-audio reasoning and fine-grained pixel understanding impose conflicting requirements on omnimodal models: dense temporal coverage demands many low-resolution frames, whereas precise grounding calls for high-resolution inputs. We tackle this trade-off with a two-system architecture: a Global Reasoning System selects informative keyframes and rewrites the task at low spatial cost, while a Detail Understanding System performs pixel-level grounding on the selected high-resolution snippets. Because optimal keyframe selection and reformulation are ambiguous and hard to supervise, we formulate them as a reinforcement-learning (RL) problem and present Omni-R1, an end-to-end RL framework built on Group Relative Policy Optimization. Omni-R1 trains the Global Reasoning System through hierarchical rewards obtained via online collaboration with the Detail Understanding System, requiring only one epoch of RL on small task splits. Experiments on two challenging benchmarks, Referring Audio-Visual Segmentation (RefAVS) and Reasoning Video Object Segmentation (REVOS), show that Omni-R1 not only surpasses strong supervised baselines but also outperforms specialized state-of-the-art models, while substantially improving out-of-domain generalization and mitigating multimodal hallucination. Our results demonstrate the first successful application of RL to large-scale omnimodal reasoning and highlight a scalable path toward universally foundation models.

State space models (SSMs) have recently garnered significant attention in computer vision. However, due to the unique characteristics of image data, adapting SSMs from natural language processing to computer vision has not outperformed the state-of-the-art convolutional neural networks (CNNs) and Vision Transformers (ViTs). Existing vision SSMs primarily leverage manually designed scans to flatten image patches into sequences locally or globally. This approach disrupts the original semantic spatial adjacency of the image and lacks flexibility, making it difficult to capture complex image structures. To address this limitation, we propose Dynamic Adaptive Scan (DAS), a data-driven method that adaptively allocates scanning orders and regions. This enables more flexible modeling capabilities while maintaining linear computational complexity and global modeling capacity. Based on DAS, we further propose the vision backbone DAMamba, which significantly outperforms popular vision Mamba models in vision tasks such as image classification, object detection, instance segmentation, and semantic segmentation.

The ability to segment objects based on open-ended language prompts remains a critical challenge, requiring models to ground textual semantics into precise spatial masks while handling diverse and unseen categories. We present OpenWorldSAM, a framework that extends the prompt-driven Segment Anything Model v2 (SAM2) to open-vocabulary scenarios by integrating multi-modal embeddings extracted from a lightweight vision-language model (VLM). Our approach is guided by four key principles: i) Unified prompting: OpenWorldSAM supports a diverse range of prompts, including category-level and sentence-level language descriptions, providing a flexible interface for various segmentation tasks.

Semantic segmentation of electron microscopy (EM) images of biological samples remains a challenge in the life sciences. EM data captures details of biological structures, sometimes with such complexity that even human observers can find it overwhelming. We introduce $\epsilon$-Seg, a method based on hierarchical variational autoencoders (HVAEs), employing center-region masking, sparse label contrastive learning (CL), a Gaussian mixture model (GMM) prior, and clustering-free label prediction. Center-region masking and the inpainting loss encourage the model to learn robust and representative embeddings to distinguish the desired classes, even if training labels are sparse ($0.05$\% of the total image data or less). For optimal performance, we employ CL and a GMM prior to shape the latent space of the HVAE such that encoded input patches tend to cluster w.r.t. the semantic classes we wish to distinguish. Finally, instead of clustering latent embeddings for semantic segmentation, we propose a MLP semantic segmentation head to directly predict class labels from latent embeddings. We show empirical results of $\epsilon$-Seg and baseline methods on $2$ dense EM datasets of biological tissues and demonstrate the applicability of our method also on fluorescence microscopy data. Our results show that $\epsilon$-Seg is capable of achieving competitive sparsely-supervised segmentation results on complex biological image data, even if only limited amounts of training labels are available.