Deep Learning
Freeze, Diffuse, Decode: Geometry-Aware Adaptation of Pretrained Transformer Embeddings for Antimicrobial Peptide Design
Gawade, Pankhil, Izdebski, Adam, Lizotte, Myriam, Moon, Kevin R., Rhodes, Jake S., Wolf, Guy, Szczurek, Ewa
Pretrained transformers provide rich, general-purpose embeddings, which are transferred to downstream tasks. However, current transfer strategies: fine-tuning and probing, either distort the pretrained geometric structure of the embeddings or lack sufficient expressivity to capture task-relevant signals. These issues become even more pronounced when supervised data are scarce. Here, we introduce Freeze, Diffuse, Decode (FDD), a novel diffusion-based framework that adapts pre-trained embeddings to downstream tasks while preserving their underlying geometric structure. FDD propagates supervised signal along the intrinsic manifold of frozen embeddings, enabling a geometry-aware adaptation of the embedding space. Applied to antimicrobial peptide design, FDD yields low-dimensional, predictive, and interpretable representations that support property prediction, retrieval, and latent-space interpolation.
Dripper: Token-Efficient Main HTML Extraction with a Lightweight LM
Liu, Mengjie, Peng, Jiahui, Chu, Pei, Qiu, Jiantao, Ma, Ren, Zhu, He, Min, Rui, Lu, Lindong, Ning, Wenchang, Hou, Linfeng, Liu, Kaiwen, Qu, Yuan, Li, Zhenxiang, Xu, Chao, Tu, Zhongying, Zhang, Wentao, He, Conghui
Accurately and efficiently extracting main content from general web pages is of great significance for obtaining training data for large models. Using well-pre-trained decoder-only generative language models offers excellent document comprehension capabilities, thereby effectively enhancing parsing quality. However, it remains constrained by issues such as context window length, inference cost, and format hallucination. We present Dripper, an efficient HTML main content extraction framework powered by lightweight language models, which addresses these challenges through four key innovations: (1) We design a specialized HTML simplification algorithm that reduces input token count to 22\% compared to raw HTML while preserving critical structural information; (2) We reformulate main content extraction as a semantic block sequence classification task, significantly reducing inference cost; (3) We introduce a controlled decoding mechanism that strictly constrains the output space through logits processors, effectively eliminating hallucination issues common in small-scale models; (4) We propose WebMainBench, an evaluation dataset containing over 7,800 web pages with meticulously human-annotated main content extraction labels. Experimental results demonstrate that using only a 0.6B parameter model, Dripper achieves state-of-the-art performance across all evaluation benchmarks and outperforms all baseline methods, attaining an ROUGE-N F1 score of 81.58\%( 83.13\% with fall-back strategy) on our proposed WebMainBench dataset.
Machine learning for violence prediction: a systematic review and critical appraisal
Kozhevnikova, Stefaniya, Yukhnenko, Denis, Scola, Giulio, Fazel, Seena
Purpose To conduct a systematic review of machine learning models for predicting violent behaviour by synthesising and appraising their validity, usefulness, and performance. Methods We systematically searched nine bibliographic databases and Google Scholar up to September 2025 for development and/or validation studies on machine learning methods for predicting all forms of violent behaviour. We synthesised the results by summarising discrimination and calibration performance statistics and evaluated study quality by examining risk of bias and clinical utility. Results We identified 38 studies reporting the development and validation of 40 models. Most studies reported Area Under the Curve (AUC) as the discrimination statistic with a range of 0.68-0.99. Only eight studies reported calibration performance, and three studies reported external validation. 31 studies had a high risk of bias, mainly in the analysis domain, and three studies had low risk of bias. The overall clinical utility of violence prediction models is poor, as indicated by risks of overfitting due to small samples, lack of transparent reporting, and low generalisability. Conclusion Although black box machine learning models currently have limited applicability in clinical settings, they may show promise for identifying high-risk individuals. We recommend five key considerations for violence prediction modelling: (i) ensuring methodological quality (e.g. following guidelines) and interdisciplinary collaborations; (ii) using black box algorithms only for highly complex data; (iii) incorporating dynamic predictions to allow for risk monitoring; (iv) developing more trustworthy algorithms using explainable methods; and (v) applying causal machine learning approaches where appropriate.
db-SP: Accelerating Sparse Attention for Visual Generative Models with Dual-Balanced Sequence Parallelism
Chen, Siqi, Hong, Ke, Zhao, Tianchen, Xie, Ruiqi, Zhu, Zhenhua, Zhang, Xudong, Wang, Yu
Scaling Diffusion Transformer (DiT) inference via sequence parallelism is critical for reducing latency in visual generation, but is severely hampered by workload imbalance when applied to models employing block-wise sparse attention. The imbalance stems from the inherent variation in sparsity across attention heads and the irregular distribution of dense blocks within the sparse mask, when sequence parallelism is applied along the head dimension (as in Ulysses) or the block dimension (as in Ring Attention). In this paper, we formalize a sparse imbalance ratio to quantify the imbalance, and propose db-SP, a sparsity-aware sequence parallelism technique that tackles the challenge. db-SP contains a dual-level partitioning approach that achieves near-perfect workload balance at both the head and block levels with negligible overhead. Furthermore, to handle the evolving sparsity patterns across denoising steps and layers, db-SP dynamically determines the parallel degrees for the head and block dimensions at runtime. Experimental results demonstrate that db-SP delivers an end-to-end speedup of 1.25x and an attention-specific speedup of 1.40x over state-of-the-art sequence parallel methods on average. Code is available at https://github.com/thu-nics/db-SP.
MathSight: A Benchmark Exploring Have Vision-Language Models Really Seen in University-Level Mathematical Reasoning?
Wang, Yuandong, Cui, Yao, Zhao, Yuxin, Yang, Zhen, Zhu, Yangfu, Shao, Zhenzhou
Recent advances in Vision-Language Models (VLMs) have achieved impressive progress in multimodal mathematical reasoning. Yet, how much visual information truly contributes to reasoning remains unclear. Existing benchmarks report strong overall performance but seldom isolate the role of the image modality, leaving open whether VLMs genuinely leverage visual understanding or merely depend on linguistic priors. To address this, we present MathSight, a university-level multimodal mathematical reasoning benchmark designed to disentangle and quantify the effect of visual input. Each problem includes multiple visual variants -- original, hand-drawn, photo-captured -- and a text-only condition for controlled comparison. Experiments on state-of-the-art VLMs reveal a consistent trend: the contribution of visual information diminishes with increasing problem difficulty. Remarkably, Qwen3-VL without any image input surpasses both its multimodal variants and GPT-5, underscoring the need for benchmarks like MathSight to advance genuine vision-grounded reasoning in future models.
Mind Reading or Misreading? LLMs on the Big Five Personality Test
Di Cursi, Francesco, Boldrini, Chiara, Conti, Marco, Passarella, Andrea
We evaluate large language models (LLMs) for automatic personality prediction from text under the binary Five Factor Model (BIG5). Five models -- including GPT-4 and lightweight open-source alternatives -- are tested across three heterogeneous datasets (Essays, MyPersonality, Pandora) and two prompting strategies (minimal vs. enriched with linguistic and psychological cues). Enriched prompts reduce invalid outputs and improve class balance, but also introduce a systematic bias toward predicting trait presence. Performance varies substantially: Openness and Agreeableness are relatively easier to detect, while Extraversion and Neuroticism remain challenging. Although open-source models sometimes approach GPT-4 and prior benchmarks, no configuration yields consistently reliable predictions in zero-shot binary settings. Moreover, aggregate metrics such as accuracy and macro-F1 mask significant asymmetries, with per-class recall offering clearer diagnostic value. These findings show that current out-of-the-box LLMs are not yet suitable for APPT, and that careful coordination of prompt design, trait framing, and evaluation metrics is essential for interpretable results.
Accent Placement Models for Rigvedic Sanskrit Text
P, Akhil Rajeev, Kulkarni, Annarao
The Rigveda, among the oldest Indian texts in Vedic Sanskrit, employs a distinctive pitch-accent system : udฤtta, anudฤtta, svarita whose marks encode melodic and interpretive cues but are often absent from modern e-texts. This work develops a parallel corpus of accented-unaccented ลlokas and conducts a controlled comparison of three strategies for automatic accent placement in Rigvedic verse: (i) full fine-tuning of ByT5, a byte-level Transformer that operates directly on Unicode combining marks, (ii) a from-scratch BiLSTM-CRF sequence-labeling baseline, and (iii) LoRA-based parameter-efficient fine-tuning atop ByT5. Evaluation uses Word Error Rate (WER) and Character Error Rate (CER) for orthographic fidelity, plus a task-specific Diacritic Error Rate (DER) that isolates accent edits. Full ByT5 fine-tuning attains the lowest error across all metrics; LoRA offers strong efficiency-accuracy trade-offs, and BiLSTM-CRF serves as a transparent baseline. The study underscores practical requirements for accent restoration - Unicode-safe preprocessing, mark-aware tokenization, and evaluation that separates grapheme from accent errors - and positions heritage-language technology as an emerging NLP area connecting computational modeling with philological and pedagogical aims. Results establish reproducible baselines for Rigvedic accent restoration and provide guidance for downstream tasks such as accent-aware OCR, ASR/chant synthesis, and digital scholarship.
Bharat Scene Text: A Novel Comprehensive Dataset and Benchmark for Indian Language Scene Text Understanding
De, Anik, Penamakuri, Abhirama Subramanyam, Yadav, Rajeev, Rathore, Aditya, Shah, Harshiv, Sharma, Devesh, Agarwal, Sagar, Kumar, Pravin, Mishra, Anand
Reading scene text, that is, text appearing in images, has numerous application areas, including assistive technology, search, and e-commerce. Although scene text recognition in English has advanced significantly and is often considered nearly a solved problem, Indian language scene text recognition remains an open challenge. This is due to script diversity, non-standard fonts, and varying writing styles, and, more importantly, the lack of high-quality datasets and open-source models. To address these gaps, we introduce the Bharat Scene Text Dataset (BSTD) - a large-scale and comprehensive benchmark for studying Indian Language Scene Text Recognition. It comprises more than 100K words that span 11 Indian languages and English, sourced from over 6,500 scene images captured across various linguistic regions of India. The dataset is meticulously annotated and supports multiple scene text tasks, including: (i) Scene Text Detection, (ii) Script Identification, (iii) Cropped Word Recognition, and (iv) End-to-End Scene Text Recognition. We evaluated state-of-the-art models originally developed for English by adapting (fine-tuning) them for Indian languages. Our results highlight the challenges and opportunities in Indian language scene text recognition. We believe that this dataset represents a significant step toward advancing research in this domain. All our models and data are open source.
Evaluating the Clinical Impact of Generative Inpainting on Bone Age Estimation
Matsuoka, Felipe Akio, Farina, Eduardo Moreno J. M., Serpa, Augusto Sarquis, Monteiro, Soraya, Ragazzini, Rodrigo, Abdala, Nitamar, Takahashi, Marcelo Straus, Kitamura, Felipe Campos
Generative foundation models can remove visual artifacts through realistic image inpainting, but their impact on medical AI performance remains uncertain. Pediatric hand radiographs often contain non-anatomical markers, and it is unclear whether inpainting these regions preserves features needed for bone age and gender prediction. To evaluate the clinical reliability of generative model-based inpainting for artifact removal, we used the RSNA Bone Age Challenge dataset, selecting 200 original radiographs and generating 600 inpainted versions with gpt-image-1 using natural language prompts to target non-anatomical artifacts. Downstream performance was assessed with deep learning ensembles for bone age estimation and gender classification, using mean absolute error (MAE) and area under the ROC curve (AUC) as metrics, and pixel intensity distributions to detect structural alterations. Inpainting markedly degraded model performance: bone age MAE increased from 6.26 to 30.11 months, and gender classification AUC decreased from 0.955 to 0.704. Inpainted images displayed pixel-intensity shifts and inconsistencies, indicating structural modifications not corrected by simple calibration. These findings show that, although visually realistic, foundation model-based inpainting can obscure subtle but clinically relevant features and introduce latent bias even when edits are confined to non-diagnostic regions, underscoring the need for rigorous, task-specific validation before integrating such generative tools into clinical AI workflows.
Standard Occupation Classifier -- A Natural Language Processing Approach
Standard Occupational Classifiers (SOC) are systems used to categorize and classify different types of jobs and occupations based on their similarities in terms of job duties, skills, and qualifications. Integrating these facets with Big Data from job advertisement offers the prospect to investigate labour demand that is specific to various occupations. This project investigates the use of recent developments in natural language processing to construct a classifier capable of assigning an occupation code to a given job advertisement. We develop various classifiers for both UK ONS SOC and US O*NET SOC, using different Language Models. We find that an ensemble model, which combines Google BERT and a Neural Network classifier while considering job title, description, and skills, achieved the highest prediction accuracy. Specifically, the ensemble model exhibited a classification accuracy of up to 61% for the lower (or fourth) tier of SOC, and 72% for the third tier of SOC. This model could provide up to date, accurate information on the evolution of the labour market using job advertisements.