Convolutional Neural Network for Automated FLAIR Lesion Segmentation on Clinical Brain MR Imaging

Next, we examined how segmentation performance varies as a function of underlying disease pathology. The CNN had significantly higher mean Dice scores than at least 1 of the other methods in 16/19 diagnoses and significantly higher than those in both other methods in 5/19 diagnoses (paired 2-tailed t tests, P .05;