Teaching computers to guide science: Machine learning method sees forests and trees: 'Iterative Random Forests' will deliver powerful scientific insights, researchers say

In a paper published recently in the Proceedings of the National Academy of Sciences (PNAS), the researchers describe a technique called "iterative Random Forests," which they say could have a transformative effect on any area of science or engineering with complex systems, including biology, precision medicine, materials science, environmental science, and manufacturing, to name a few. "Take a human cell, for example. There are 10170 possible molecular interactions in a single cell. That creates considerable computing challenges in searching for relationships," said Ben Brown, head of Berkeley Lab's Molecular Ecosystems Biology Department. "Our method enables the identification of interactions of high order at the same computational cost as main effects -- even when those interactions are local with weak marginal effects."