MiDeSeC: A Dataset for Mitosis Detection and Segmentation in Breast Cancer Histopathology Images

Samet, Refik, Nemati, Nooshin, Hancer, Emrah, Sak, Serpil, Kirmizi, Bilge Ayca, Yildirim, Zeynep

arXiv.org Artificial Intelligence 

Prof. Dr. Bilge Ayca Kirmizi, akarabork@yahoo.com 1 Introduction Nottingham Grading System [1] emphasizes three key morphological features on Hematoxylin and Eosin (H&E) stained slides to grade breast cancer: mitotic count, tubule formation, and nuclear pleomorphism. Mitotic count is the most prominent feature among them. Searching for mitosis on glass slides is a routine procedure for breast pathologists. Since there are so many high power fields (HPFs) on a single slide and mitotic cells vary in appearance, it is a tedious and time - consuming task. Additionally, mitotic cell judgment is somewhat subjective, making it difficult for pathologists to reach a consensus. Thus, it is extremely important to develop automatic detection methods that will not only save time and material resources, but will also enhance the reliability of pathological diagnosis.