Mobile-use agents powered by vision-language models (VLMs) have shown great potential in interpreting natural language instructions and generating corresponding actions based on mobile graphical user interface. Recent studies suggest that incorporating chain-of-thought (CoT) reasoning tends to improve the execution accuracy. However, existing evaluations emphasize execution accuracy while neglecting whether CoT reasoning aligns with ground-truth actions. This oversight fails to assess potential reasoning-execution gaps, which in turn foster over-trust: users relying on seemingly plausible CoTs may unknowingly authorize harmful actions, potentially resulting in financial loss or trust crisis. In this work, we introduce a new evaluation framework to diagnose reasoning-execution gaps. At its core lies Ground-Truth Alignment (GTA), which measures whether the action implied by a CoT matches the ground-truth action. By combining GTA with the standard Exact Match (EM) metric, we jointly assess both the reasoning accuracy and execution accuracy. This joint perspective reveals two types of reasoning-execution gaps: (i) Execution Gap (EG), where the reasoning correctly identifies the correct action but execution fails, and (ii) Reasoning Gap (RG), where execution succeeds but reasoning process conflicts with the actual execution. Experimental results across a wide range of mobile interaction tasks reveal that reasoning-execution gaps are prevalent, with execution gaps occurring more frequently than reasoning gaps. Moreover, while scaling up model size reduces the overall gap, sizable execution gaps persist even in the largest models. Further analysis shows that our framework reliably reflects systematic EG/RG patterns in state-of-the-art models. These findings offer concrete diagnostics and support the development of more trustworthy mobile-use agents.

Fuzz testing has become a cornerstone technique for identifying software bugs and security vulnerabilities, with broad adoption in both industry and open-source communities. Directly fuzzing a function requires fuzz drivers, which translate random fuzzer inputs into valid arguments for the target function. Given the cost and expertise required to manually develop fuzz drivers, methods exist that leverage program analysis and Large Language Models to automatically generate these drivers. However, the generated fuzz drivers frequently lead to false positive crashes, especially in functions highly structured input and complex state requirements. This problem is especially crucial in industry-scale fuzz driver generation efforts like OSS-Fuzz-en, as reporting false positive crashes to maintainers impede trust in both the system and the team. This paper presents two AI-driven strategies to reduce false positives in OSS-Fuzz-Gen, a multi-agent system for automated fuzz driver generation. First, constraint-based fuzz driver generation proactively enforces constraints on a function's inputs and state to guide driver creation. Second, context-based crash validation reactively analyzes function callers to determine whether reported crashes are feasible from program entry points. Using 1,500 benchmark functions from OSS-Fuzz, we show that these strategies reduce spurious crashes by up to 8%, cut reported crashes by more than half, and demonstrate that frontier LLMs can serve as reliable program analysis agents. Our results highlight the promise and challenges of integrating AI into large-scale fuzzing pipelines.

3D indoor layout synthesis is crucial for creating virtual environments. Traditional methods struggle with generalization due to fixed datasets. While recent LLM and VLM-based approaches offer improved semantic richness, they often lack robust and flexible refinement, resulting in suboptimal layouts. We develop DisCo-Layout, a novel framework that disentangles and coordinates physical and semantic refinement. For independent refinement, our Semantic Refinement Tool (SRT) corrects abstract object relationships, while the Physical Refinement Tool (PRT) resolves concrete spatial issues via a grid-matching algorithm. For collaborative refinement, a multi-agent framework intelligently orchestrates these tools, featuring a planner for placement rules, a designer for initial layouts, and an evaluator for assessment. Experiments demonstrate DisCo-Layout's state-of-the-art performance, generating realistic, coherent, and generalizable 3D indoor layouts. Our code will be publicly available.

Abstract--Bioinformatics tools are essential for complex computational biology tasks, yet their integration with emerging AI-agent frameworks is hindered by incompatible interfaces, heterogeneous input-output formats, and inconsistent parameter conventions. The Model Context Protocol (MCP) provides a standardized framework for tool-AI communication, but manually converting hundreds of existing and rapidly growing specialized bioinformatics tools into MCP-compliant servers is labor-intensive and unsustainable. Here, we present BioinfoMCP, a unified platform comprising two components: BioinfoMCP Converter, which automatically generates robust MCP servers from tool documentation using large language models, and BioinfoMCP Benchmark, which systematically validates the reliability and versatility of converted tools across diverse computational tasks. We present a platform of 38 MCP-converted bioinformatics tools, extensively validated to show that 94.7% successfully executed complex workflows across three widely used AI-agent platforms. By removing technical barriers to AI automation, BioinfoMCP enables natural-language interaction with sophisticated bioinformatics analyses without requiring extensive programming expertise, offering a scalable path to intelligent, interoperable computational biology . The bioinformatics landscape is characterized by an extensive ecosystem of specialized tools designed for diverse analytical tasks that serve critical functions in genomics [1], proteomics [2], [3], and molecular biology [4], and so on.

This paper addresses a critical aerial defense challenge in contested airspace, involving three autonomous aerial vehicles -- a hostile drone (the pursuer), a high-value drone (the evader), and a protective drone (the defender). We present a cooperative guidance framework for the evader-defender team that guarantees interception of the pursuer before it can capture the evader, even under highly dynamic and uncertain engagement conditions. Unlike traditional heuristic, optimal control, or differential game-based methods, we approach the problem within a time-constrained guidance framework, leveraging true proportional navigation based approach that ensures robust and guaranteed solutions to the aerial defense problem. The proposed strategy is computationally lightweight, scalable to a large number of agent configurations, and does not require knowledge of the pursuer's strategy or control laws. From arbitrary initial geometries, our method guarantees that key engagement errors are driven to zero within a fixed time, leading to a successful mission. Extensive simulations across diverse and adversarial scenarios confirm the effectiveness of the proposed strategy and its relevance for real-time autonomous defense in contested airspace environments.

In a time of rapidly evolving military threats and increasingly complex operational environments, the integration of AI into military operations proves significant advantages. At the same time, this implies various challenges and risks regarding building and deploying human-AI teaming systems in an effective and ethical manner. Currently, understanding and coping with them are often tackled from an external perspective considering the human-AI teaming system as a collective agent. Nevertheless, zooming into the dynamics involved inside the system assures dealing with a broader palette of relevant multidimensional responsibility, safety, and robustness aspects. To this end, this research proposes the design of a trustworthy co-learning model for human-AI teaming in military operations that encompasses a continuous and bidirectional exchange of insights between the human and AI agents as they jointly adapt to evolving battlefield conditions. It does that by integrating four dimensions. First, adjustable autonomy for dynamically calibrating the autonomy levels of agents depending on aspects like mission state, system confidence, and environmental uncertainty. Second, multi-layered control which accounts continuous oversight, monitoring of activities, and accountability. Third, bidirectional feedback with explicit and implicit feedback loops between the agents to assure a proper communication of reasoning, uncertainties, and learned adaptations that each of the agents has. And fourth, collaborative decision-making which implies the generation, evaluation, and proposal of decisions associated with confidence levels and rationale behind them. The model proposed is accompanied by concrete exemplifications and recommendations that contribute to further developing responsible and trustworthy human-AI teaming systems in military operations.

Abstract--Secure and interoperable integration of heterogeneous medical data remains a grand challenge in digital health. Current federated learning (FL) frameworks offer privacy-preserving model training but lack standardized mechanisms to orchestrate multi-modal data fusion across distributed and resource-constrained environments. This study introduces a novel framework that leverages the Model Context Protocol (MCP) as an interoperability layer for secure, cross-agent communication in multi-modal federated healthcare systems. The proposed architecture unifies three pillars: (i) multi-modal feature alignment for clinical imaging, electronic medical records, and wearable IoT data; (ii) secure aggregation with differential privacy to protect patient-sensitive updates; and (iii) energy-aware scheduling to mitigate dropouts in mobile clients. By employing MCP as a schema-driven interface, the framework enables adaptive orchestration of AI agents and toolchains while ensuring compliance with privacy regulations. Experimental evaluation on benchmark datasets and pilot clinical cohorts demonstrates up to 9.8% improvement in diagnostic accuracy compared with baseline FL, a 54% reduction in client dropout rates, and clinically acceptable privacy-utility trade-offs.

Abstract-- Modern automated factories increasingly run manufacturing procedures using a matrix of programmable machines, such as 3D printers, interconnected by a programmable transport system, such as a fleet of tabletop robots. T o embed a manufacturing procedure into a smart factory, an operator must: (a) assign each of its processes to a machine and (b) specify how agents should transport parts between machines. The problem of embedding a manufacturing process into a smart factory is termed the Smart Factory Embedding (SFE) problem. State-of-the-art SFE solvers can only scale to factories containing a couple dozen machines. Modern smart factories, however, may contain hundreds of machines. We fill this hole by introducing the first highly scalable solution to the SFE, TS-ACES, the Traffic System based Anytime Cyclic Embedding Solver . We show that TS-ACES is complete and can scale to SFE instances based on real industrial scenarios with more than a hundred machines. I. INTRODUCTION Flexible manufacturing is a key objective of the modern manufacturing industry [1]. A smart factory is flexible if it can be easily reconfigured to produce different products.

This paper presents a novel, structured decision support framework that systematically aligns diverse artificial intelligence (AI) agent architectures, reactive, cognitive, hybrid, and learning, with the comprehensive National Institute of Standards and Technology (NIST) Cybersecurity Framework (CSF) 2.0. By integrating agent theory with industry guidelines, this framework provides a transparent and stepwise methodology for selecting and deploying AI solutions to address contemporary cyber threats. Employing a granular decomposition of NIST CSF 2.0 functions into specific tasks, the study links essential AI agent properties such as autonomy, adaptive learning, and real-time responsiveness to each subcategory's security requirements. In addition, it outlines graduated levels of autonomy (assisted, augmented, and fully autonomous) to accommodate organisations at varying stages of cybersecurity maturity. This holistic approach transcends isolated AI applications, providing a unified detection, incident response, and governance strategy. Through conceptual validation, the framework demonstrates how tailored AI agent deployments can align with real-world constraints and risk profiles, enhancing situational awareness, accelerating response times, and fortifying long-term resilience via adaptive risk management. Ultimately, this research bridges the gap between theoretical AI constructs and operational cybersecurity demands, establishing a foundation for robust, empirically validated multi-agent systems that adhere to industry standards.

Computer-Use Agents (CUAs) are an increasingly deployed class of agents that take actions on GUIs to accomplish user goals. In this paper, we show that CUAs consistently exhibit Blind Goal-Directedness (BGD): a bias to pursue goals regardless of feasibility, safety, reliability, or context. We characterize three prevalent patterns of BGD: (i) lack of contextual reasoning, (ii) assumptions and decisions under ambiguity, and (iii) contradictory or infeasible goals. We develop BLIND-ACT, a benchmark of 90 tasks capturing these three patterns. Built on OSWorld, BLIND-ACT provides realistic environments and employs LLM-based judges to evaluate agent behavior, achieving 93.75% agreement with human annotations. We use BLIND-ACT to evaluate nine frontier models, including Claude Sonnet and Opus 4, Computer-Use-Preview, and GPT-5, observing high average BGD rates (80.8%) across them. We show that BGD exposes subtle risks that arise even when inputs are not directly harmful. While prompting-based interventions lower BGD levels, substantial risk persists, highlighting the need for stronger training- or inference-time interventions. Qualitative analysis reveals observed failure modes: execution-first bias (focusing on how to act over whether to act), thought-action disconnect (execution diverging from reasoning), and request-primacy (justifying actions due to user request). Identifying BGD and introducing BLIND-ACT establishes a foundation for future research on studying and mitigating this fundamental risk and ensuring safe CUA deployment.