Purpose: Autonomous navigation of devices in endovascular interventions can decrease operation times, improve decision-making during surgery, and reduce operator radiation exposure while increasing access to treatment. This systematic review explores recent literature to assess the impact, challenges, and opportunities artificial intelligence (AI) has for the autonomous endovascular intervention navigation. Methods: PubMed and IEEEXplore databases were queried. Eligibility criteria included studies investigating the use of AI in enabling the autonomous navigation of catheters/guidewires in endovascular interventions. Following PRISMA, articles were assessed using QUADAS-2. PROSPERO: CRD42023392259. Results: Among 462 studies, fourteen met inclusion criteria. Reinforcement learning (9/14, 64%) and learning from demonstration (7/14, 50%) were used as data-driven models for autonomous navigation. Studies predominantly utilised physical phantoms (10/14, 71%) and in silico (4/14, 29%) models. Experiments within or around the blood vessels of the heart were reported by the majority of studies (10/14, 71%), while simple non-anatomical vessel platforms were used in three studies (3/14, 21%), and the porcine liver venous system in one study. We observed that risk of bias and poor generalisability were present across studies. No procedures were performed on patients in any of the studies reviewed. Studies lacked patient selection criteria, reference standards, and reproducibility, resulting in low clinical evidence levels. Conclusions: AI's potential in autonomous endovascular navigation is promising, but in an experimental proof-of-concept stage, with a technology readiness level of 3. We highlight that reference standards with well-identified performance metrics are crucial to allow for comparisons of data-driven algorithms proposed in the years to come.

Robotic affordances, providing information about what actions can be taken in a given situation, can aid robotic manipulation. However, learning about affordances requires expensive large annotated datasets of interactions or demonstrations. In this work, we argue that well-directed interactions with the environment can mitigate this problem and propose an information-based measure to augment the agent's objective and accelerate the affordance discovery process. We provide a theoretical justification of our approach and we empirically validate the approach both in simulation and real-world tasks. Our method, which we dub IDA, enables the efficient discovery of visual affordances for several action primitives, such as grasping, stacking objects, or opening drawers, strongly improving data efficiency in simulation, and it allows us to learn grasping affordances in a small number of interactions, on a real-world setup with a UFACTORY XArm 6 robot arm.

All of these applications involve active interactions with the environment, from which observations are made in Reinforcement Learning (RL) is the process by which an agent learns order to train the RL agent. Extending RL to real-world applications optimal behavior through interactions with experience datasets, all presents challenges, particularly in scenarios such as self-driving of which aim to maximize the reward signal. RL algorithms often cars, where exploration and training in the field can be impractical face performance challenges in real-world applications, especially and may even raise safety concerns while piloting a car due to when training with extensive and diverse datasets. For instance, delayed decisions stemming from the performance bottlenecks of applications like autonomous vehicles include sensory data, dynamic underlying RL-based decision-making modules [6, 7].

Despite notable successes of Reinforcement Learning (RL), the prevalent use of an online learning paradigm prevents its widespread adoption, especially in hazardous or costly scenarios. Offline RL has emerged as an alternative solution, learning from pre-collected static datasets. However, this offline learning introduces a new challenge known as distributional shift, degrading the performance when the policy is evaluated on scenarios that are Out-Of-Distribution (OOD) from the training dataset. Most existing offline RL resolves this issue by regularizing policy learning within the information supported by the given dataset. However, such regularization overlooks the potential for high-reward regions that may exist beyond the dataset. This motivates exploring novel offline learning techniques that can make improvements beyond the data support without compromising policy performance, potentially by learning causation (cause-and-effect) instead of correlation from the dataset. In this paper, we propose the MOOD-CRL (Model-based Offline OOD-Adapting Causal RL) algorithm, which aims to address the challenge of extrapolation for offline policy training through causal inference instead of policy-regularizing methods. Specifically, Causal Normalizing Flow (CNF) is developed to learn the transition and reward functions for data generation and augmentation in offline policy evaluation and training. Based on the data-invariant, physics-based qualitative causal graph and the observational data, we develop a novel learning scheme for CNF to learn the quantitative structural causal model. As a result, CNF gains predictive and counterfactual reasoning capabilities for sequential decision-making tasks, revealing a high potential for OOD adaptation. Our CNF-based offline RL approach is validated through empirical evaluations, outperforming model-free and model-based methods by a significant margin.

Adversarial machine learning, focused on studying various attacks and defenses on machine learning (ML) models, is rapidly gaining importance as ML is increasingly being adopted for optimizing wireless systems such as Open Radio Access Networks (O-RAN). A comprehensive modeling of the security threats and the demonstration of adversarial attacks and defenses on practical AI based O-RAN systems is still in its nascent stages. We begin by conducting threat modeling to pinpoint attack surfaces in O-RAN using an ML-based Connection management application (xApp) as an example. The xApp uses a Graph Neural Network trained using Deep Reinforcement Learning and achieves on average 54% improvement in the coverage rate measured as the 5th percentile user data rates. We then formulate and demonstrate evasion attacks that degrade the coverage rates by as much as 50% through injecting bounded noise at different threat surfaces including the open wireless medium itself. Crucially, we also compare and contrast the effectiveness of such attacks on the ML-based xApp and a non-ML based heuristic. We finally develop and demonstrate robust training-based defenses against the challenging physical/jamming-based attacks and show a 15% improvement in the coverage rates when compared to employing no defense over a range of noise budgets

This paper presents a framework for learning state and action abstractions in sequential decision-making domains. Our framework, planning abstraction from language (PARL), utilizes language-annotated demonstrations to automatically discover a symbolic and abstract action space and induce a latent state abstraction based on it. PARL consists of three stages: 1) recovering object-level and action concepts, 2) learning state abstractions, abstract action feasibility, and transition models, and 3) applying low-level policies for abstract actions. During inference, given the task description, PARL first makes abstract action plans using the latent transition and feasibility functions, then refines the high-level plan using low-level policies. PARL generalizes across scenarios involving novel object instances and environments, unseen concept compositions, and tasks that require longer planning horizons than settings it is trained on.

As the last critical stage of RSs, Multi-Task Fusion (MTF) is responsible for combining multiple scores outputted by Multi-Task Learning (MTL) into a final score to maximize user satisfaction, which determines the ultimate recommendation results. Recently, to optimize long-term user satisfaction within a recommendation session, Reinforcement Learning (RL) is used for MTF in the industry. However, the off-policy RL algorithms used for MTF so far have the following severe problems: 1) to avoid out-of-distribution (OOD) problem, their constraints are overly strict, which seriously damage their performance; 2) they are unaware of the exploration policy used for producing training data and never interact with real environment, so only suboptimal policy can be learned; 3) the traditional exploration policies are inefficient and hurt user experience. To solve the above problems, we propose a novel method named IntegratedRL-MTF customized for MTF in large-scale RSs. IntegratedRL-MTF integrates off-policy RL model with our online exploration policy to relax overstrict and complicated constraints, which significantly improves its performance. We also design an extremely efficient exploration policy, which eliminates low-value exploration space and focuses on exploring potential high-value state-action pairs. Moreover, we adopt progressive training mode to further enhance our model's performance with the help of our exploration policy. We conduct extensive offline and online experiments in the short video channel of Tencent News. The results demonstrate that our model outperforms other models remarkably. IntegratedRL-MTF has been fully deployed in our RS and other large-scale RSs in Tencent, which have achieved significant improvements.

Learning from Demonstration allows robots to mimic human actions. However, these methods do not model constraints crucial to ensure safety of the learned skill. Moreover, even when explicitly modelling constraints, they rely on the assumption of a known cost function, which limits their practical usability for task with unknown cost. In this work we propose a two-step optimization process that allow to estimate cost and constraints by decoupling the learning of cost functions from the identification of unknown constraints within the demonstrated trajectories. Initially, we identify the cost function by isolating the effect of constraints on parts of the demonstrations. Subsequently, a constraint leaning method is used to identify the unknown constraints. Our approach is validated both on simulated trajectories and a real robotic manipulation task. Our experiments show the impact that incorrect cost estimation has on the learned constraints and illustrate how the proposed method is able to infer unknown constraints, such as obstacles, from demonstrated trajectories without any initial knowledge of the cost.

AlphaFold can be used for both single-chain and multi-chain protein structure prediction, while the latter becomes extremely challenging as the number of chains increases. In this work, by taking each chain as a node and assembly actions as edges, we show that an acyclic undirected connected graph can be used to predict the structure of multi-chain protein complexes (a.k.a., protein complex modelling, PCM). To address these challenges, we propose GAPN, a Generative Adversarial Policy Network powered by domainspecific rewards and adversarial loss through policy gradient for automatic PCM prediction. Specifically, GAPN learns to efficiently search through the immense assembly space and optimize the direct docking reward through policy gradient. Importantly, we design an adversarial reward function to enhance the receptive field of our model. In this way, GAPN will simultaneously focus on a specific batch of complexes and the global assembly rules learned from complexes with varied chain numbers. Empirically, we have achieved both significant accuracy (measured by RMSD and TM-Score) and efficiency improvements compared to leading PCM softwares. AlphaFold-Multimer (Evans et al., 2021) has However, it faces difficulties in maintaining high accuracy when dealing with complexes with a larger number (> 9) of chains (Bryant et al., 2022a; Burke et al., 2023; Bryant et al., 2022b).

Therefore, to transfer a policy on the source robot to multiple target robots, they must launch multiple independent runs for each target robot. We investigate the problem of transferring an expert policy from a source robot to multiple different robots. To solve this problem, we propose a method named Meta-Evolve that uses continuous robot evolution to efficiently transfer the policy to each target robot through a set of tree-structured evolutionary robot sequences. The robot evolution tree allows the robot evolution paths to be shared, so our approach can significantly outperform naive one-to-one policy transfer. We present a heuristic approach to determine an optimized robot evolution tree. Experiments have shown that our method is able to improve the efficiency of one-to-three transfer of manipulation policy by up to 3.2 and one-to-six transfer of agile locomotion policy by 2.4 in terms of simulation cost over the baseline of launching multiple independent one-to-one policy transfers. The robotics industry has designed and developed a large number of commercial robots deployed in various applications. How to efficiently learn robotic skills on diverse robots in a scalable fashion? A popular solution is to train a policy for every new robot on every new task from scratch. This is not only inefficient in terms of sample efficiency but also impractical for complex robots due to a large exploration space. Inter-robot imitation by statistic matching methods that optimize to match the distribution of actions (Ross et al., 2011), transitioned states (Liu et al., 2019; Radosavovic et al., 2020), or reward (Ng et al., 2000; Ho & Ermon, 2016) could be possible solutions. However, they can only be applied to robots with similar dynamics to yield optimal performance. Recent advances in evolution-based imitation learning (Liu et al., 2022a;b) inspire us to view this problem from the perspective of policy transferring from one robot to another. The core idea is to interpolate two different robots by producing a large number of intermediate robots between them which gradually evolve from the source robot toward the target robot.