Multimodal data analysis can lead to more accurate diagnoses of brain disorders due to the complementary information that each modality adds. However, a major challenge of using multimodal datasets in the neuroimaging field is incomplete data, where some of the modalities are missing for certain subjects. Hence, effective strategies are needed for completing the data. Traditional methods, such as subsampling or zero-filling, may reduce the accuracy of predictions or introduce unintended biases. In contrast, advanced methods such as generative models have emerged as promising solutions without these limitations. In this study, we proposed a generative adversarial network method designed to reconstruct missing modalities from existing ones while preserving the disease patterns. We used T1-weighted structural magnetic resonance imaging and functional network connectivity as two modalities. Our findings showed a 9% improvement in the classification accuracy for Alzheimer's disease versus cognitive normal groups when using our generative imputation method compared to the traditional approaches.

Retrieval-Augmented Generation (RAG) and its Multimodal Retrieval-Augmented Generation (MRAG) significantly improve the knowledge coverage and contextual understanding of Large Language Models (LLMs) by introducing external knowledge sources. However, retrieval and multimodal fusion obscure content provenance, rendering existing membership inference methods unable to reliably attribute generated outputs to pre-training, external retrieval, or user input, thus undermining privacy leakage accountability To address these challenges, we propose the first Source-aware Membership Audit (SMA) that enables fine-grained source attribution of generated content in a semi-black-box setting with retrieval control capabilities. To address the environmental constraints of semi-black-box auditing, we further design an attribution estimation mechanism based on zero-order optimization, which robustly approximates the true influence of input tokens on the output through large-scale perturbation sampling and ridge regression modeling. In addition, SMA introduces a cross-modal attribution technique that projects image inputs into textual descriptions via MLLMs, enabling token-level attribution in the text modality, which for the first time facilitates membership inference on image retrieval traces in MRAG systems. This work shifts the focus of membership inference from 'whether the data has been memorized' to 'where the content is sourced from', offering a novel perspective for auditing data provenance in complex generative systems.

-- Detecting driver fatigue is critical for road safety, as drowsy driving remains a leading cause of traffic accidents. Many existing solutions rely on computationally demanding deep learning models, which result in high latency and are unsuitable for embedded robotic devices with limited resources (such as intelligent vehicles/cars) where rapid detection is necessary to prevent accidents. This paper introduces LiteFat, a lightweight spatio-temporal graph learning model designed to detect driver fatigue efficiently while maintaining high accuracy and low computational demands. LiteFat involves converting streaming video data into spatio-temporal graphs (STG) using facial landmark detection, which focuses on key motion patterns and reduces unnecessary data processing. LiteFat uses MobileNet to extract facial features and create a feature matrix for the STG. A lightweight spatio-temporal graph neural network is then employed to identify signs of fatigue with minimal processing and low latency. Experimental results on benchmark datasets show that LiteFat performs competitively while significantly reduced computational complexity and latency as compared to current state-of-the-art methods. This work advances the development of real-time, resource-efficient human fatigue detection systems that can be implemented upon embedded robotic devices. Driver fatigue is a major contributor to traffic accidents worldwide, posing a significant threat to road safety [1].

Large, publicly available clinical datasets have emerged as a novel resource for understanding disease heterogeneity and to explore personalization of therapy. These datasets are derived from data not originally collected for research purposes and, as a result, are often incomplete and lack critical labels. Many AI tools have been developed to retrospectively label these datasets, such as by performing disease classification; however, they often suffer from limited interpretability. Previous work has attempted to explain predictions using Concept Bottleneck Models (CBMs), which learn interpretable concepts that map to higher-level clinical ideas, facilitating human evaluation. However, these models often experience performance limitations when the concepts fail to adequately explain or characterize the task. We use the identification of Acute Respiratory Distress Syndrome (ARDS) as a challenging test case to demonstrate the value of incorporating contextual information from clinical notes to improve CBM performance. Our approach leverages a Large Language Model (LLM) to process clinical notes and generate additional concepts, resulting in a 10% performance gain over existing methods.

Malware detection increasingly relies on AI systems that integrate signature-based detection with machine learning. However, these components are typically developed and combined in isolation, missing opportunities to reduce data complexity and strengthen defenses against adversarial EXEmples, carefully crafted programs designed to evade detection. Hence, in this work we investigate the influence that signature-based detection exerts on model training, when they are included inside the training pipeline. Specifically, we compare models trained on a comprehensive dataset with an AI system whose machine learning component is trained solely on samples not already flagged by signatures. Our results demonstrate improved robustness to both adversarial EXEmples and temporal data drift, although this comes at the cost of a fixed lower bound on false positives, driven by suboptimal rule selection. We conclude by discussing these limitations and outlining how future research could extend AI-based malware detection to include dynamic analysis, thereby further enhancing system resilience.

With the growing complexity of cyberattacks targeting critical infrastructures such as water treatment networks, there is a pressing need for robust anomaly detection strategies that account for both system vulnerabilities and evolving attack patterns. Traditional methods -- statistical, density-based, and graph-based models struggle with distribution shifts and class imbalance in multivariate time series, often leading to high false positive rates. To address these challenges, we propose CGAD, a Causal Graph-based Anomaly Detection framework designed for reliable cyberattack detection in public infrastructure systems. CGAD follows a two-phase supervised framework -- causal profiling and anomaly scoring. First, it learns causal invariant graph structures representing the system's behavior under "Normal" and "Attack" states using Dynamic Bayesian Networks. Second, it employs structural divergence to detect anomalies via causal graph comparison by evaluating topological deviations in causal graphs over time. By leveraging causal structures, CGAD achieves superior adaptability and accuracy in non-stationary and imbalanced time series environments compared to conventional machine learning approaches. By uncovering causal structures beneath volatile sensor data, our framework not only detects cyberattacks with markedly higher precision but also redefines robustness in anomaly detection, proving resilience where traditional models falter under imbalance and drift. Our framework achieves substantial gains in F1 and ROC-AUC scores over best-performing baselines across four industrial datasets, demonstrating robust detection of delayed and structurally complex anomalies.

Recent breakthroughs in large language models (LLMs) have opened the door to in-depth investigation of their potential in tabular data modeling. However, effectively utilizing advanced LLMs in few-shot and even zero-shot scenarios is still challenging. To this end, we propose a novel LLM-based prototype estimation framework for tabular learning. Our key idea is to query the LLM to generate feature values based example-free prompt, which solely relies on task and feature descriptions. With the feature values generated by LLM, we can build a zero-shot prototype in a training-free manner, which can be further enhanced by fusing few-shot samples, avoiding training a classifier or finetuning the LLMs. Thanks to the example-free prompt and prototype estimation, ours bypasses the constraints brought by the example-based prompt, providing a scalable and robust framework. Extensive experiments demonstrate the effectiveness of ours in zero and few-shot tabular learning.

Recent advances in machine learning have greatly expanded the repertoire of predictive methods for medical imaging. However, the interpretability of complex models remains a challenge, which limits their utility in medical applications. Recently, model-agnostic methods have been proposed to measure conditional variable importance and accommodate complex non-linear models. However, they often lack power when dealing with highly correlated data, a common problem in medical imaging. We introduce Hierarchical-CPI, a model-agnostic variable importance measure that frames the inference problem as the discovery of groups of variables that are jointly predictive of the outcome. By exploring subgroups along a hierarchical tree, it remains computationally tractable, yet also enjoys explicit family-wise error rate control. Moreover, we address the issue of vanishing conditional importance under high correlation with a tree-based importance allocation mechanism. We benchmarked Hierarchical-CPI against state-of-the-art variable importance methods. Its effectiveness is demonstrated in two neuroimaging datasets: classifying dementia diagnoses from MRI data (ADNI dataset) and analyzing the Berger effect on EEG data (TDBRAIN dataset), identifying biologically plausible variables.

Natural disasters such as hurricanes and wildfires increasingly introduce unusual disturbance on economic activities, which are especially likely to reshape commercial land use pattern given their sensitive to customer visitation. However, current modeling approaches are limited in capturing such complex interplay between human activities and commercial land use change under and following disturbances. Such interactions have been more effectively captured in current resilient urban planning theories. This study designs and calibrates a Urban Theory-Informed Spatio-Temporal Attention Model for Predicting Post-Disaster Commercial Land Use Change (Urban-STA4CLC) to predict both the yearly decline and expansion of commercial land use at census block level under cumulative impact of disasters on human activities over two years. Guided by urban theories, Urban-STA4CLC integrates both spatial and temporal attention mechanisms with three theory-informed modules. Resilience theory guides a disaster-aware temporal attention module that captures visitation dynamics. Spatial economic theory informs a multi-relational spatial attention module for inter-block representation. Diffusion theory contributes a regularization term that constrains land use transitions. The model performs significantly better than non-theoretical baselines in predicting commercial land use change under the scenario of recurrent hurricanes, with around 19% improvement in F1 score (0.8763). The effectiveness of the theory-guided modules was further validated through ablation studies. The research demonstrates that embedding urban theory into commercial land use modeling models may substantially enhance the capacity to capture its gains and losses. These advances in commercial land use modeling contribute to land use research that accounts for cumulative impacts of recurrent disasters and shifts in economic activity patterns.

Magnetic resonance (MR) imaging is essential for evaluating central nervous system (CNS) tumors, guiding surgical planning, treatment decisions, and assessing postoperative outcomes and complication risks. While recent work has advanced automated tumor segmentation and report generation, most efforts have focused on preoperative data, with limited attention to postoperative imaging analysis. This study introduces a comprehensive pipeline for standardized postsurtical reporting in CNS tumors. Using the Attention U-Net architecture, segmentation models were trained for the preoperative (non-enhancing) tumor core, postoperative contrast-enhancing residual tumor, and resection cavity. Additionally, MR sequence classification and tumor type identification for contrast-enhancing lesions were explored using the DenseNet architecture. The models were integrated into a reporting pipeline, following the RANO 2.0 guidelines. Training was conducted on multicentric datasets comprising 2000 to 7000 patients, using a 5-fold cross-validation. Evaluation included patient-, voxel-, and object-wise metrics, with benchmarking against the latest BraTS challenge results. The segmentation models achieved average voxel-wise Dice scores of 87%, 66%, 70%, and 77% for the tumor core, non-enhancing tumor core, contrast-enhancing residual tumor, and resection cavity, respectively. Classification models reached 99.5% balanced accuracy in MR sequence classification and 80% in tumor type classification. The pipeline presented in this study enables robust, automated segmentation, MR sequence classification, and standardized report generation aligned with RANO 2.0 guidelines, enhancing postoperative evaluation and clinical decision-making. The proposed models and methods were integrated into Raidionics, open-source software platform for CNS tumor analysis, now including a dedicated module for postsurgical analysis.