The global rise in type 2 diabetes underscores the need for scalable and cost-effective screening methods. Current diagnosis requires biochemical assays, which are invasive and costly. Advances in consumer wearables have enabled early explorations of machine learning-based disease detection, but prior studies were limited to controlled settings. We present SweetDeep, a compact neural network trained on physiological and demographic data from 285 (diabetic and non-diabetic) participants in the EU and MENA regions, collected using Samsung Galaxy Watch 7 devices in free-living conditions over six days. Each participant contributed multiple 2-minute sensor recordings per day, totaling approximately 20 recordings per individual. Despite comprising fewer than 3,000 parameters, SweetDeep achieves 82.5% patient-level accuracy (82.1% macro-F1, 79.7% sensitivity, 84.6% specificity) under three-fold cross-validation, with an expected calibration error of 5.5%. Allowing the model to abstain on less than 10% of low-confidence patient predictions yields an accuracy of 84.5% on the remaining patients. These findings demonstrate that combining engineered features with lightweight architectures can support accurate, rapid, and generalizable detection of type 2 diabetes in real-world wearable settings.

Abstract--The widespread adoption of large language models (LLMs) has made it difficult to distinguish human writing from machine-produced text in many real applications. Detectors that were effective for one generation of models tend to degrade when newer models or modified decoding strategies are introduced. In this work, we study this lack of stability and propose a hybrid ensemble that is explicitly designed to cope with changing generator distributions. The ensemble combines three complementary components: a RoBERT a-based classifier fine-tuned for supervised detection, a curvature-inspired score based on perturbing the input and measuring changes in model likelihood, and a compact stylometric model built on handcrafted linguistic features. The outputs of these components are fused on the probability simplex, and the weights are chosen via validation-based search. We frame this approach in terms of variance reduction and risk under mixtures of generators, and show that the simplex constraint provides a simple way to trade off the strengths and weaknesses of each branch. Experiments on a 30 000-document corpus drawn from several LLM families including models unseen during training and paraphrased attack variants show that the proposed method achieves 94.2% accuracy and an AUC of 0.978. The ensemble also lowers false positives on scientific articles compared to strong baselines, which is critical in educational and research settings where wrongly flagging human work is costly. Text generated by large language models (LLMs) is now routinely used in homework, reports, programming, and informal communication.

Existing Grammatical Error Correction (GEC) systems suffer from limited reference diversity, leading to underestimated evaluation and restricted model generalization. To address this issue, we introduce the Judge of Edit-Level Validity (JELV), an automated framework to validate correction edits from grammaticality, faithfulness, and fluency. Using our proposed human-annotated Pair-wise Edit-level Validity Dataset (PEVData) as benchmark, JELV offers two implementations: a multi-turn LLM-as-Judges pipeline achieving 90% agreement with human annotators, and a distilled DeBERTa classifier with 85% precision on valid edits. We then apply JELV to reclassify misjudged false positives in evaluation and derive a comprehensive evaluation metric by integrating false positive decoupling and fluency scoring, resulting in state-of-the-art correlation with human judgments. We also apply JELV to filter LLM-generated correction candidates, expanding the BEA19's single-reference dataset containing 38,692 source sentences. Retraining top GEC systems on this expanded dataset yields measurable performance gains. JELV provides a scalable solution for enhancing reference diversity and strengthening both evaluation and model generalization.

Detecting regime shifts in chaotic time series is difficult because observation-space signals are entangled with intrinsic variability. We propose Parameter-Space Changepoint Detection (Param-CPD), a two-stage framework that first amortizes Bayesian inference of governing parameters with a neural posterior estimator trained by simulation-based inference, and then applies a standard CPD algorithm to the resulting parameter trajectory. In Lorenz-63 with piecewise-constant parameters, Param-CPD improves F1, reduces localization error, and reduces false positives compared to baselines of observation-space. We further verify identifiability and calibration of the inferred posteriors on stationary trajectories, explaining why parameter space offers a cleaner detection signal. Robustness analyzes of tolerance, window length, and noise indicate consistent gains. Our results show that operating in a physically interpretable parameter space enables accurate and interpretable changepoint detection in nonlinear dynamical systems.

Universal multimodal embedding models are foundational to various tasks. Existing approaches typically employ in-batch negative mining by measuring the similarity of query-candidate pairs. However, these methods often struggle to capture subtle semantic differences among candidates and lack diversity in negative samples. Moreover, the embeddings exhibit limited discriminative ability in distinguishing false and hard negatives. In this paper, we leverage the advanced understanding capabilities of MLLMs to enhance representation learning and present a novel Universal Multimodal Embedding (UniME-V2) model. Our approach first constructs a potential hard negative set through global retrieval. We then introduce the MLLM-as-a-Judge mechanism, which utilizes MLLMs to assess the semantic alignment of query-candidate pairs and generate soft semantic matching scores. These scores serve as a foundation for hard negative mining, mitigating the impact of false negatives and enabling the identification of diverse, high-quality hard negatives. Furthermore, the semantic matching scores are used as soft labels to mitigate the rigid one-to-one mapping constraint. By aligning the similarity matrix with the soft semantic matching score matrix, the model learns semantic distinctions among candidates, significantly enhancing its discriminative capacity. To further improve performance, we propose UniME-V2-Reranker, a reranking model trained on our mined hard negatives through a joint pairwise and listwise optimization approach. We conduct comprehensive experiments on the MMEB benchmark and multiple retrieval tasks, demonstrating that our method achieves state-of-the-art performance on average across all tasks.

Retrosynthesis is one of the domains transformed by the rise of generative models, and it is one where the problem of nonsensical or erroneous outputs (hallucinations) is particularly insidious: reliable assessment of synthetic plans is time-consuming, with automatic methods lacking. In this work, we present RetroTrim, a retrosynthesis system that successfully avoids nonsensical plans on a set of challenging drug-like targets. Compared to common baselines in the field, our system is not only the sole method that succeeds in filtering out hallucinated reactions, but it also results in the highest number of high-quality paths overall. The key insight behind RetroTrim is the combination of diverse reaction scoring strategies, based on machine learning models and existing chemical databases. We show that our scoring strategies capture different classes of hallucinations by analyzing them on a dataset of labeled retrosynthetic intermediates. This approach formed the basis of our winning solution to the Standard Industries \$1 million Retrosynthesis Challenge. To measure the performance of retrosynthesis systems, we propose a novel evaluation protocol for reactions and synthetic paths based on a structured review by expert chemists. Using this protocol, we compare systems on a set of 32 novel targets, curated to reflect recent trends in drug structures. While the insights behind our methodology are broadly applicable to retrosynthesis, our focus is on targets in the drug-like domain. By releasing our benchmark targets and the details of our evaluation protocol, we hope to inspire further research into reliable retrosynthesis.

Cardiovascular diseases (CVDs) are the leading cause of death worldwide, accounting for approximately 17.9 million deaths each year. Early detection is critical, creating a demand for accurate and inexpensive pre-screening methods. Deep learning has recently been applied to classify abnormal heart sounds indicative of CVDs using synchronised phonocardiogram (PCG) and electrocardiogram (ECG) signals, as well as multichannel PCG (mPCG). However, state-of-the-art architectures remain underutilised due to the limited availability of synchronised and multichannel datasets. Augmented datasets and pre-trained models provide a pathway to overcome these limitations, enabling transformer-based architectures to be trained effectively. This work combines traditional signal processing with denoising diffusion models, WaveGrad and DiffWave, to create an augmented dataset to fine-tune a Wav2Vec 2.0-based classifier on multimodal and multichannel heart sound datasets. The approach achieves state-of-the-art performance. On the Computing in Cardiology (CinC) 2016 dataset of single channel PCG, accuracy, unweighted average recall (UAR), sensitivity, specificity and Matthew's correlation coefficient (MCC) reach 92.48%, 93.05%, 93.63%, 92.48%, 94.93% and 0.8283, respectively. Using the synchronised PCG and ECG signals of the training-a dataset from CinC, 93.14%, 92.21%, 94.35%, 90.10%, 95.12% and 0.8380 are achieved for accuracy, UAR, sensitivity, specificity and MCC, respectively. Using a wearable vest dataset consisting of mPCG data, the model achieves 77.13% accuracy, 74.25% UAR, 86.47% sensitivity, 62.04% specificity, and 0.5082 MCC. These results demonstrate the effectiveness of transformer-based models for CVD detection when supported by augmented datasets, highlighting their potential to advance multimodal and multichannel heart sound classification.

The Maximum Clique Problem (MCP) is a foundational NP-hard problem with wide-ranging applications, yet no single algorithm consistently outperforms all others across diverse graph instances. This underscores the critical need for instance-aware algorithm selection, a domain that remains largely unexplored for the MCP. To address this gap, we propose a novel learning-based framework that integrates both traditional machine learning and graph neural networks. We first construct a benchmark dataset by executing four state-of-the-art exact MCP solvers on a diverse collection of graphs and extracting their structural features. An evaluation of conventional classifiers establishes Random Forest as a strong baseline and reveals that connectivity and topological features are key predictors of performance. Building on these insights, we develop GAT-MLP, a dual-channel model that combines a Graph Attention Network (GAT) to encode local graph structure with a Multilayer Perceptron (MLP) to model global features. Extensive experiments demonstrate that GAT-MLP achieves superior and consistent performance, significantly outperforming all baseline methods. Our results highlight the effectiveness of the dual-channel architecture and the promise of graph neural networks for combinatorial algorithm selection, achieving 90.43% accuracy in choosing the optimal solver. Code and models are available at: https://anonymous.4open.science/r/GAT-MLP-7E5F.

Watermarking is a promising defense against the misuse of large language models (LLMs), yet it remains vulnerable to scrubbing and spoofing attacks. This vulnerability stems from an inherent trade-off governed by watermark window size: smaller windows resist scrubbing better but are easier to reverse-engineer, enabling low-cost statistics-based spoofing attacks. This work breaks this trade-off by introducing a novel mechanism, equivalent texture keys, where multiple tokens within a watermark window can independently support the detection. Based on the redundancy, we propose a novel watermark scheme with Sub-vocabulary decomposed Equivalent tExture Key (SEEK). It achieves a Pareto improvement, increasing the resilience against scrubbing attacks without compromising robustness to spoofing. Experiments demonstrate SEEK's superiority over prior method, yielding spoofing robustness gains of +88.2%/+92.3%/+82.0% and scrubbing robustness gains of +10.2%/+6.4%/+24.6% across diverse dataset settings.

For any black-box model, conformal prediction (CP) returns prediction sets guaranteed to include the true label with high adjustable probability. Robust CP (RCP) extends the guarantee to the worst case noise up to a pre-defined magnitude. For RCP, a well-established approach is to use randomized smoothing since it is applicable to any black-box model and provides smaller sets compared to deterministic methods. However, smoothing-based robustness requires many model forward passes per each input which is computationally expensive. We show that conformal prediction attains some robustness even with a single forward pass on a randomly perturbed input. Using any binary certificate we propose a single sample robust CP (RCP1). Our approach returns robust sets with smaller average set size compared to SOTA methods which use many (e.g. 100) passes per input. Our key insight is to certify the conformal procedure itself rather than individual conformity scores. Our approach is agnostic to the task (classification and regression). We further extend our approach to smoothing-based robust conformal risk control.