Existing data-driven approaches in modeling and predicting time series data include ARIMA (Autoregressive Integrated Moving Average), Transformer-based models, LSTM (Long Short-Term Memory) and TCN (Temporal Convolutional Network). These approaches, and in particular deep learning-based models such as LSTM and TCN, have shown great results in predicting time series data. With the advancement of leveraging pre-trained foundation models such as Large Language Models (LLMs) and more notably Google's recent foundation model for time series data, {\it TimesFM} (Time Series Foundation Model), it is of interest to investigate whether these foundation models have the capability of outperforming existing modeling approaches in analyzing and predicting time series data. This paper investigates the performance of using LLM models for time series data prediction. We investigate the in-context learning methodology in the training of LLM models that are specific to the underlying application domain. More specifically, the paper explores training LLMs through in-context, zero-shot and few-shot learning and forecasting time series data with OpenAI {\tt o4-mini} and Gemini 2.5 Flash Lite, as well as the recent Google's Transformer-based TimesFM, a time series-specific foundation model, along with two deep learning models, namely TCN and LSTM networks. The findings indicate that TimesFM has the best overall performance with the lowest RMSE value (0.3023) and the competitive inference time (266 seconds). Furthermore, OpenAI's o4-mini also exhibits a good performance based on Zero Shot learning. These findings highlight pre-trained time series foundation models as a promising direction for real-time forecasting, enabling accurate and scalable deployment with minimal model adaptation.

Large foundation models have emerged in the last years and are pushing performance boundaries for a variety of tasks. Training or even finetuning such models demands vast datasets and computational resources, which are often scarce and costly. Adaptation methods provide a computationally efficient solution to address these limitations by allowing such models to be finetuned on small amounts of data and computing power . This is achieved by appending new trainable modules to frozen backbones with only a fraction of the trainable parameters and fitting only these modules on novel tasks. Recently, the V eRA adapter was shown to excel in parameter-efficient adaptations by utilizing a pair of frozen random low-rank matrices shared across all layers. In this paper, we propose PV eRA, a probabilistic version of the V eRA adapter, which modifies the low-rank matrices of V eRA in a probabilistic manner . This modification naturally allows handling inherent ambiguities in the input and allows for different sampling configurations during training and testing. A comprehensive evaluation was performed on the VTAB-1k benchmark and seven adapters, with PV eRA outperforming V eRA and other adapters. Our code for training models with PV eRA and benchmarking all adapters is available here.

In pre-market drug safety review, grouping related adverse event terms into standardised MedDRA queries or the FDA Office of New Drugs Custom Medical Queries (OCMQs) is critical for signal detection. We present a novel quantitative artificial intelligence system that understands and processes medical terminology and automatically retrieves relevant MedDRA Preferred Terms (PTs) for a given input query, ranking them by a relevance score using multi-criteria statistical methods. The system (SafeTerm) embeds medical query terms and MedDRA PTs in a multidimensional vector space, then applies cosine similarity and extreme-value clustering to generate a ranked list of PTs. Validation was conducted against the FDA OCMQ v3.0 (104 queries), restricted to valid MedDRA PTs. Precision, recall and F1 were computed across similarity-thresholds. High recall (>95%) is achieved at moderate thresholds. Higher thresholds improve precision (up to 86%). The optimal threshold (~0.70 - 0.75) yielded recall ~50% and precision ~33%. Narrow-term PT subsets performed similarly but required slightly higher similarity thresholds. The SafeTerm AI-driven system provides a viable supplementary method for automated MedDRA query generation. A similarity threshold of ~0.60 is recommended initially, with increased thresholds for refined term selection.

Deep learning holds immense promise for transforming medical image analysis, yet its clinical generalization remains profoundly limited. A major barrier is data heterogeneity. This is particularly true in Magnetic Resonance Imaging, where scanner hardware differences, diverse acquisition protocols, and varying sequence parameters introduce substantial domain shifts that obscure underlying biological signals. Data harmonization methods aim to reduce these instrumental and acquisition variability, but existing approaches remain insufficient. When applied to imaging data, image-based harmonization approaches are often restricted by the need for target images, while existing text-guided methods rely on simplistic labels that fail to capture complex acquisition details or are typically restricted to datasets with limited variability, failing to capture the heterogeneity of real-world clinical environments. To address these limitations, we propose DIST-CLIP (Disentangled Style Transfer with CLIP Guidance), a unified framework for MRI harmonization that flexibly uses either target images or DICOM metadata for guidance. Our framework explicitly disentangles anatomical content from image contrast, with the contrast representations being extracted using pre-trained CLIP encoders. These contrast embeddings are then integrated into the anatomical content via a novel Adaptive Style Transfer module. We trained and evaluated DIST-CLIP on diverse real-world clinical datasets, and showed significant improvements in performance when compared against state-of-the-art methods in both style translation fidelity and anatomical preservation, offering a flexible solution for style transfer and standardizing MRI data. Our code and weights will be made publicly available upon publication.

Effective motion representation is crucial for enabling robots to imitate expressive behaviors in real time, yet existing motion controllers often ignore inherent patterns in motion. Previous efforts in representation learning do not attempt to jointly capture structured periodic patterns and irregular variations in human and animal movement. To address this, we present Multi-Domain Motion Embedding (MDME), a motion representation that unifies the embedding of structured and unstructured features using a wavelet-based encoder and a probabilistic embedding in parallel. This produces a rich representation of reference motions from a minimal input set, enabling improved generalization across diverse motion styles and morphologies. We evaluate MDME on retargeting-free real-time motion imitation by conditioning robot control policies on the learned embeddings, demonstrating accurate reproduction of complex trajectories on both humanoid and quadruped platforms. Our comparative studies confirm that MDME outperforms prior approaches in reconstruction fidelity and generalizability to unseen motions. Furthermore, we demonstrate that MDME can reproduce novel motion styles in real-time through zero-shot deployment, eliminating the need for task-specific tuning or online retargeting. These results position MDME as a generalizable and structure-aware foundation for scalable real-time robot imitation.

Large Language Models (LLMs) have demonstrated remarkable performance in code intelligence tasks such as code generation, summarization, and translation. However, their reliance on linearized token sequences limits their ability to understand the structural semantics of programs. While prior studies have explored graphaugmented prompting and structure-aware pretraining, they either suffer from prompt length constraints or require task-specific architectural changes that are incompatible with large-scale instructionfollowing LLMs. To address these limitations, this paper proposes CGBridge, a novel plug-and-play method that enhances LLMs with Code Graph information through an external, trainable Bridge module. CGBridge first pre-trains a code graph encoder via selfsupervised learning on a large-scale dataset of 270K code graphs to learn structural code semantics. It then trains an external module to bridge the modality gap among code, graph, and text by aligning their semantics through cross-modal attention mechanisms. Finally, the bridge module generates structure-informed prompts, which are injected into a frozen LLM, and is fine-tuned for downstream code intelligence tasks. Experiments show that CGBridge achieves notable improvements over both the original model and the graphaugmented prompting method. Specifically, it yields a 16.19% and 9.12% relative gain in LLM-as-a-Judge on code summarization, and a 9.84% and 38.87% relative gain in Execution Accuracy on code translation. Moreover, CGBridge achieves over 4x faster inference than LoRA-tuned models, demonstrating both effectiveness and efficiency in structure-aware code understanding.

Transformer architectures offer significant advantages regarding the generation of symbolic music; their capabilities for incorporating user preferences toward what they generate is being studied under many aspects. This paper studies the inclusion of predefined chord constraints in melodic harmonization, i.e., where a desired chord at a specific location is provided along with the melody as inputs and the autoregressive transformer model needs to incorporate the chord in the harmonization that it generates. The peculiarities of involving such constraints is discussed and an algorithm is proposed for tackling this task. This algorithm is called B* and it combines aspects of beam search and A* along with backtracking to force pretrained transformers to satisfy the chord constraints, at the correct onset position within the correct bar. The algorithm is brute-force and has exponential complexity in the worst case; however, this paper is a first attempt to highlight the difficulties of the problem and proposes an algorithm that offers many possibilities for improvements since it accommodates the involvement of heuristics.

Process Model Forecasting (PMF) aims to predict how the control-flow structure of a process evolves over time by mode ling the temporal dynamics of directly-follows (DF) relations, comple menting predictive process monitoring that focuses on single-case prefixe s. Prior benchmarks show that machine learning and deep learning models pr ovide only modest gains over statistical baselines, mainly due to the s parsity and heterogeneity of the DF time series. We investigate Time Ser ies Foundation Models (TSFMs), large pre-trained models for generic t ime series, as an alternative for PMF. Using DF time series derived from rea l-life event logs, we compare zero-shot use of TSFMs, without additional training, with fine-tuned variants adapted on PMF-specific data. TSFMs generally achieve lower forecasting errors (MAE and RMSE) than tradit ional and specialized models trained from scratch on the same logs, in dicating effective transfer of temporal structure from non-process do mains. While fine-tuning can further improve accuracy, the gains are ofte n small and may disappear on smaller or more complex datasets, so zero-s hot use remains a strong default. Our study highlights the generaliza tion capability and data efficiency of TSFMs for process-related time series a nd, to the best of our knowledge, provides the first systematic evaluat ion of temporal foundation models for PMF.

We introduce \emph{Metric-Fair Prompting}, a fairness-aware prompting framework that guides large language models (LLMs) to make decisions under metric-fairness constraints. In the application of multiple-choice medical question answering, each {(question, option)} pair is treated as a binary instance with label $+1$ (correct) or $-1$ (incorrect). To promote {individual fairness}~--~treating similar instances similarly~--~we compute question similarity using NLP embeddings and solve items in \emph{joint pairs of similar questions} rather than in isolation. The prompt enforces a global decision protocol: extract decisive clinical features, map each \((\text{question}, \text{option})\) to a score $f(x)$ that acts as confidence, and impose a Lipschitz-style constraint so that similar inputs receive similar scores and, hence, consistent outputs. Evaluated on the {MedQA (US)} benchmark, Metric-Fair Prompting is shown to improve performance over standard single-item prompting, demonstrating that fairness-guided, confidence-oriented reasoning can enhance LLM accuracy on high-stakes clinical multiple-choice questions.

Developing robust and general-purpose manipulation policies represents a fundamental objective in robotics research. While Vision-Language-Action (VLA) models have demonstrated promising capabilities for end-to-end robot control, existing approaches still exhibit limited generalization to tasks beyond their training distributions. In contrast, humans possess remarkable proficiency in acquiring novel skills by simply observing others performing them once. Inspired by this capability, we propose ViVLA, a generalist robotic manipulation policy that achieves efficient task learning from a single expert demonstration video at test time. Our approach jointly processes an expert demonstration video alongside the robot's visual observations to predict both the demonstrated action sequences and subsequent robot actions, effectively distilling fine-grained manipulation knowledge from expert behavior and transferring it seamlessly to the agent. To enhance the performance of ViVLA, we develop a scalable expert-agent pair data generation pipeline capable of synthesizing paired trajectories from easily accessible human videos, further augmented by curated pairs from publicly available datasets. This pipeline produces a total of 892,911 expert-agent samples for training ViVLA. Experimental results demonstrate that our ViVLA is able to acquire novel manipulation skills from only a single expert demonstration video at test time. Our approach achieves over 30% improvement on unseen LIBERO tasks and maintains above 35% gains with cross-embodiment videos. Real-world experiments demonstrate effective learning from human videos, yielding more than 38% improvement on unseen tasks.