Myofascial pain (MP) is a leading cause of chronic low back pain, yet its tissue-level drivers remain poorly defined and lack reliable image biomarkers. Existing studies focus predominantly on muscle while neglecting fascia, fat, and other soft tissues that play integral biomechanical roles. We developed an anatomically grounded explainable artificial intelligence (AI) framework, LAYER (Layer-wise Analysis for Yielding Explainable Relevance Tissue), that analyses six tissue layers in three-dimensional (3D) ultrasound and quantifies their contribution to MP prediction. By utilizing the largest multi-model 3D ultrasound cohort consisting of over 4,000 scans, LAYER reveals that non-muscle tissues contribute substantially to pain prediction. In B-mode imaging, the deep fascial membrane (DFM) showed the highest saliency (0.420), while in combined B-mode and shear-wave images, the collective saliency of non-muscle layers (0.316) nearly matches that of muscle (0.317), challenging the conventional muscle-centric paradigm in MP research and potentially affecting the therapy methods. LAYER establishes a quantitative, interpretable framework for linking layer-specific anatomy to pain physiology, uncovering new tissue targets and providing a generalizable approach for explainable analysis of soft-tissue imaging.

Large Language Models (LLMs) have demonstrated strong translation abilities through prompting, even without task-specific training. However, their effectiveness in dialectal and low-resource contexts remains underexplored. This study presents the first systematic investigation of LLM-based machine translation (MT) for Sylheti, a dialect of Bangla that is itself low-resource. We evaluate five advanced LLMs (GPT-4.1, GPT-4.1, LLaMA 4, Grok 3, and DeepSeek V3.2) across both translation directions (Bangla $\Leftrightarrow$ Sylheti), and find that these models struggle with dialect-specific vocabulary. To address this, we introduce Sylheti-CAP (Context-Aware Prompting), a three-step framework that embeds a linguistic rulebook, a dictionary (2{,}260 core vocabulary items and idioms), and an authenticity check directly into prompts. Extensive experiments show that Sylheti-CAP consistently improves translation quality across models and prompting strategies. Both automatic metrics and human evaluations confirm its effectiveness, while qualitative analysis reveals notable reductions in hallucinations, ambiguities, and awkward phrasing, establishing Sylheti-CAP as a scalable solution for dialectal and low-resource MT. Dataset link: \href{https://github.com/TabiaTanzin/LLMs-for-Low-Resource-Dialect-Translation-Using-Context-Aware-Prompting-A-Case-Study-on-Sylheti.git}{https://github.com/TabiaTanzin/LLMs-for-Low-Resource-Dialect-Translation-Using-Context-Aware-Prompting-A-Case-Study-on-Sylheti.git}

Large language model (LLM) services have been rapidly integrated into people's daily lives as chatbots and agentic systems. They are nourished by collecting rich streams of data, raising privacy concerns around excessive collection of sensitive personal information. Privacy policies are the fundamental mechanism for informing users about data practices in modern information privacy paradigm. Although traditional web and mobile policies are well studied, the privacy policies of LLM providers, their LLM-specific content, and their evolution over time remain largely underexplored. In this paper, we present the first longitudinal empirical study of privacy policies for mainstream LLM providers worldwide. We curate a chronological dataset of 74 historical privacy policies and 115 supplemental privacy documents from 11 LLM providers across 5 countries up to August 2025, and extract over 3,000 sentence-level edits between consecutive policy versions. We compare LLM privacy policies to those of other software formats, propose a taxonomy tailored to LLM privacy policies, annotate policy edits and align them with a timeline of key LLM ecosystem events. Results show they are substantially longer, demand college-level reading ability, and remain highly vague. Our taxonomy analysis reveals patterns in how providers disclose LLM-specific practices and highlights regional disparities in coverage. Policy edits are concentrated in first-party data collection and international/specific-audience sections, and that product releases and regulatory actions are the primary drivers, shedding light on the status quo and the evolution of LLM privacy policies.

The integration of Large Language Models (LLMs) into healthcare demands a safety paradigm rooted in \textit{primum non nocere}. However, current alignment techniques rely on generic definitions of harm that fail to capture context-dependent violations, such as administrative fraud and clinical discrimination. To address this, we introduce Medical Malice: a dataset of 214,219 adversarial prompts calibrated to the regulatory and ethical complexities of the Brazilian Unified Health System (SUS). Crucially, the dataset includes the reasoning behind each violation, enabling models to internalize ethical boundaries rather than merely memorizing a fixed set of refusals. Using an unaligned agent (Grok-4) within a persona-driven pipeline, we synthesized high-fidelity threats across seven taxonomies, ranging from procurement manipulation and queue-jumping to obstetric violence. We discuss the ethical design of releasing these "vulnerability signatures" to correct the information asymmetry between malicious actors and AI developers. Ultimately, this work advocates for a shift from universal to context-aware safety, providing the necessary resources to immunize healthcare AI against the nuanced, systemic threats inherent to high-stakes medical environments -- vulnerabilities that represent the paramount risk to patient safety and the successful integration of AI in healthcare systems.

Large-scale disasters can often result in catastrophic consequences on people and infrastructure. Situation awareness about such disaster impacts generated by authoritative data from in-situ sensors, remote sensing imagery, and/or geographic data is often limited due to atmospheric opacity, satellite revisits, and time limitations. This often results in geo-temporal information gaps. In contrast, impact-related social media posts can act as "geo-sensors" during a disaster, where people describe specific impacts and locations. However, not all locations mentioned in disaster-related social media posts relate to an impact. Only the impacted locations are critical for directing resources effectively. e.g., "The death toll from a fire which ripped through the Greek coastal town of #Mati stood at 80, with dozens of people unaccounted for as forensic experts tried to identify victims who were burned alive #Greecefires #AthensFires #Athens #Greece." contains impacted location "Mati" and non-impacted locations "Greece" and "Athens". This research uses Large Language Models (LLMs) to identify all locations, impacts and impacted locations mentioned in disaster-related social media posts. In the process, LLMs are fine-tuned to identify only impacts and impacted locations (as distinct from other, non-impacted locations), including locations mentioned in informal expressions, abbreviations, and short forms. Our fine-tuned model demonstrates efficacy, achieving an F1-score of 0.69 for impact and 0.74 for impacted location extraction, substantially outperforming the pre-trained baseline. These robust results confirm the potential of fine-tuned language models to offer a scalable solution for timely decision-making in resource allocation, situational awareness, and post-disaster recovery planning for responders.

The discovery of next-generation photoinitiators for two-photon polymerization (TPP) is hindered by the absence of large, open datasets containing the quantum-chemical and photophysical properties required to model photodissociation and excited-state behavior. Existing molecular datasets typically provide only basic physicochemical descriptors and therefore cannot support data-driven screening or AI-assisted design of photoinitiators. To address this gap, we introduce QuantumChem-200K, a large-scale dataset of over 200,000 organic molecules annotated with eleven quantum-chemical properties, including two-photon absorption (TPA) cross sections, TPA spectral ranges, singlet-triplet intersystem crossing (ISC) energies, toxicity and synthetic accessibility scores, hydrophilicity, solubility, boiling point, molecular weight, and aromaticity. These values are computed using a hybrid workflow that integrates density function theory (DFT), semi-empirical excited-state methods, atomistic quantum solvers, and neural-network predictors. Using QuantumChem-200K, we fine tune the open-source Qwen2.5-32B large language model to create a chemistry AI assistant capable of forward property prediction from SMILES. Benchmarking on 3000 unseen molecules from VQM24 and ZINC20 demonstrates that domain-specific fine-tuning significantly improves accuracy over GPT-4o, Llama-3.1-70B, and the base Qwen2.5-32B model, particularly for TPA and ISC predictions central to photoinitiator design. QuantumChem-200K and the corresponding AI assistant together provide the first scalable platform for high-throughput, LLM-driven photoinitiator screening and accelerated discovery of photosensitive materials.

We analyze reasoning in language models during task-specific fine-tuning and draws parallel between reasoning tokens--intermediate steps generated while solving problem and the human working memory. Drawing from cognitive science, we align training dynamics with the Four Stages of Competence: models initially produce incorrect outputs without reasoning, then begin reasoning (but still fail), eventually reason effectively, and finally solve tasks without explicit reasoning. We find that reasoning token length expands as performance improves, peaks at the stage of conscious competence, then declines as the model internalizes the task. Notably, after training, models retain performance even when reasoning is removed--suggesting it scaffolded learning but is no longer needed. This progression offers actionable insights: reasoning token dynamics can serve as a signal for diagnosing training stage, identifying convergence, and guiding early stopping. We propose metrics to track this trajectory and argue that reasoning behavior is valuable for understanding and optimizing reasoning model training.

With the growing use of Large Language Model (LLM)- based Question-Answering (QA) systems in education, it is critical to evaluate their performance across individual pipeline components. In this work, we introduce EduMod-LLM, a modular function-calling LLM pipeline, and present a comprehensive evaluation along three key axes: function calling strategies, retrieval methods, and generative language models. Our framework enables fine-grained analysis by isolating and assessing each component. We benchmark function-calling performance across LLMs, compare our novel structure-aware retrieval method to vector-based and LLM-scoring baselines, and evaluate various LLMs for response synthesis. This modular approach reveals specific failure modes and performance patterns, supporting the development of interpretable and effective educational QA systems. Our findings demonstrate the value of modular function calling in improving system transparency and pedagogical alignment.

We present the first large-scale analysis of AI foundation model usage in science - not just citations or keywords. We find that adoption has grown rapidly, at nearly-exponential rates, with the highest uptake in Linguistics, Computer Science, and Engineering. Vision models are the most used foundation models in science, although language models' share is growing. Open-weight models dominate. As AI builders increase the parameter counts of their models, scientists have followed suit but at a much slower rate: in 2013, the median foundation model built was 7.7x larger than the median one adopted in science, by 2024 this had jumped to 26x. We also present suggestive evidence that scientists' use of these smaller models may be limiting them from getting the full benefits of AI-enabled science, as papers that use larger models appear in higher-impact journals and accrue more citations.

AI-assisted report generation offers the opportunity to reduce radiologists' workload stemming from expanded screening guidelines, complex cases and workforce shortages, while maintaining diagnostic accuracy. In addition to describing pathological findings in chest X-ray reports, interpreting lines and tubes (L&T) is demanding and repetitive for radiologists, especially with high patient volumes. We introduce MAIRA-X, a clinically evaluated multimodal AI model for longitudinal chest X-ray (CXR) report generation, that encompasses both clinical findings and L&T reporting. Developed using a large-scale, multi-site, longitudinal dataset of 3.1 million studies (comprising 6 million images from 806k patients) from Mayo Clinic, MAIRA-X was evaluated on three holdout datasets and the public MIMIC-CXR dataset, where it significantly improved AI-generated reports over the state of the art on lexical quality, clinical correctness, and L&T-related elements. A novel L&T-specific metrics framework was developed to assess accuracy in reporting attributes such as type, longitudinal change and placement. A first-of-its-kind retrospective user evaluation study was conducted with nine radiologists of varying experience, who blindly reviewed 600 studies from distinct subjects. The user study found comparable rates of critical errors (3.0% for original vs. 4.6% for AI-generated reports) and a similar rate of acceptable sentences (97.8% for original vs. 97.4% for AI-generated reports), marking a significant improvement over prior user studies with larger gaps and higher error rates. Our results suggest that MAIRA-X can effectively assist radiologists, particularly in high-volume clinical settings.