Computed tomography (CT) provides highly detailed three-dimensional (3D) medical images but is costly, time-consuming, and often inaccessible in intraoperative settings (Organization et al. 2011). Recent advancements have explored reconstructing 3D chest volumes from sparse 2D X-rays, such as single-view or orthogonal double-view images. However, current models tend to process 2D images in a planar manner, prioritizing visual realism over structural accuracy. In this work, we introduce DuoLift Generative Adversarial Networks (DuoLift-GAN), a novel architecture with dual branches that independently elevate 2D images and their features into 3D representations. These 3D outputs are merged into a unified 3D feature map and decoded into a complete 3D chest volume, enabling richer 3D information capture. We also present a masked loss function that directs reconstruction towards critical anatomical regions, improving structural accuracy and visual quality. This paper demonstrates that DuoLift-GAN significantly enhances reconstruction accuracy while achieving superior visual realism compared to existing methods.

We introduce Concept Bottleneck Protein Language Models (CB-pLM), a generative masked language model with a layer where each neuron corresponds to an interpretable concept. Our architecture offers three key benefits: i) Control: We can intervene on concept values to precisely control the properties of generated proteins, achieving a 3 times larger change in desired concept values compared to baselines. ii) Interpretability: A linear mapping between concept values and predicted tokens allows transparent analysis of the model's decision-making process. iii) Debugging: This transparency facilitates easy debugging of trained models. Our models achieve pre-training perplexity and downstream task performance comparable to traditional masked protein language models, demonstrating that interpretability does not compromise performance. While adaptable to any language model, we focus on masked protein language models due to their importance in drug discovery and the ability to validate our model's capabilities through real-world experiments and expert knowledge. We scale our CB-pLM from 24 million to 3 billion parameters, making them the largest Concept Bottleneck Models trained and the first capable of generative language modeling.

Sequential recommendation systems aim to provide personalized recommendations for users based on their interaction history. To achieve this, they often incorporate auxiliary information, such as textual descriptions of items and auxiliary tasks, like predicting user preferences and intent. Despite numerous efforts to enhance these models, they still suffer from limited personalization. To address this issue, we propose a new paradigm, which we term preference discerning. In preference dscerning, we explicitly condition a generative sequential recommendation system on user preferences within its context. To this end, we generate user preferences using Large Language Models (LLMs) based on user reviews and item-specific data. To evaluate preference discerning capabilities of sequential recommendation systems, we introduce a novel benchmark that provides a holistic evaluation across various scenarios, including preference steering and sentiment following. We assess current state-of-the-art methods using our benchmark and show that they struggle to accurately discern user preferences. Therefore, we propose a new method named Mender ($\textbf{M}$ultimodal Prefer$\textbf{en}$ce $\textbf{d}$iscern$\textbf{er}$), which improves upon existing methods and achieves state-of-the-art performance on our benchmark. Our results show that Mender can be effectively guided by human preferences even though they have not been observed during training, paving the way toward more personalized sequential recommendation systems. We will open-source the code and benchmarks upon publication.

When finetuning multiple tasks altogether, it is important to carefully weigh them to get a good performance, but searching for good weights can be difficult and costly. Here, we propose to aid the search with fast previews to quickly get a rough idea of different reweighting options. We use model merging to create previews by simply reusing and averaging parameters of models trained on each task separately (no retraining required). To improve the quality of previews, we propose a Bayesian approach to design new merging strategies by using more flexible posteriors. We validate our findings on vision and natural-language transformers. Our work shows the benefits of model merging via Bayes to improve multitask finetuning.

Internet services have led to the eruption of network traffic, and machine learning on these Internet data has become an indispensable tool, especially when the application is risk-sensitive. This paper focuses on network traffic classification in the presence of severe class imbalance. Such a distributional trait mostly drifts the optimal decision boundary and results in an unsatisfactory solution. This raises safety concerns in the network traffic field when previous class imbalance methods hardly deal with numerous minority malicious classes. To alleviate these effects, we design a \textit{group \& reweight} strategy for alleviating class imbalance. Inspired by the group distributionally optimization framework, our approach heuristically clusters classes into groups, iteratively updates the non-parametric weights for separate classes, and optimizes the learning model by minimizing reweighted losses. We theoretically interpret the optimization process from a Stackelberg game and perform extensive experiments on typical benchmarks. Results show that our approach can not only suppress the negative effect of class imbalance but also improve the comprehensive performance in prediction.

Hershey shares jump on Cadbury owner buyout report Getty ImagesMondelez has reportedly made a preliminary approach to the maker of the iconic Hershey's milk chocolate bar Shares in US chocolate maker Hershey have jumped by more than 10% after a report that Mondelez International, which owns UK-based Cadbury, has approached the firm about a potential buyout. A deal could create a snack food giant with combined sales of almost 50bn ( 39.2bn) a year. Both Mondelez and Hershey declined to comment on the report when contacted by BBC News. In 2016, Hershey rejected a 23bn takeover offer from Mondelez. The approach is still in the preliminary stages and it is not certain that talks will lead to a deal, according to Bloomberg.

Thomas C. Schelling, awarded the 2005 Nobel Memorial Prize in Economic Sciences, pointed out that ``individuals decisions (micromotives), while often personal and localized, can lead to societal outcomes (macrobehavior) that are far more complex and different from what the individuals intended.'' The current research related to large language models' (LLMs') micromotives, such as preferences or biases, assumes that users will make more appropriate decisions once LLMs are devoid of preferences or biases. Consequently, a series of studies has focused on removing bias from LLMs. In the NLP community, while there are many discussions on LLMs' micromotives, previous studies have seldom conducted a systematic examination of how LLMs may influence society's macrobehavior. In this paper, we follow the design of Schelling's model of segregation to observe the relationship between the micromotives and macrobehavior of LLMs. Our results indicate that, regardless of the level of bias in LLMs, a highly segregated society will emerge as more people follow LLMs' suggestions. We hope our discussion will spark further consideration of the fundamental assumption regarding the mitigation of LLMs' micromotives and encourage a reevaluation of how LLMs may influence users and society.

Modeling user preferences has been mainly addressed by looking at users' interaction history with the different elements available in the system. Tailoring content to individual preferences based on historical data is the main goal of sequential recommendation. The nature of the problem, as well as the good performance observed across various domains, has motivated the use of the transformer architecture, which has proven effective in leveraging increasingly larger amounts of training data when accompanied by an increase in the number of model parameters. This scaling behavior has brought a great deal of attention, as it provides valuable guidance in the design and training of even larger models. Taking inspiration from the scaling laws observed in training large language models, we explore similar principles for sequential recommendation. We use the full Amazon Product Data dataset, which has only been partially explored in other studies, and reveal scaling behaviors similar to those found in language models. Compute-optimal training is possible but requires a careful analysis of the compute-performance trade-offs specific to the application. We also show that performance scaling translates to downstream tasks by fine-tuning larger pre-trained models on smaller task-specific domains. Our approach and findings provide a strategic roadmap for model training and deployment in real high-dimensional preference spaces, facilitating better training and inference efficiency. We hope this paper bridges the gap between the potential of transformers and the intrinsic complexities of high-dimensional sequential recommendation in real-world recommender systems. Code and models can be found at https://github.com/mercadolibre/srt

Integrating AI into education has the potential to transform the teaching of science and technology courses, particularly in the field of cybersecurity. AI-driven question-answering (QA) systems can actively manage uncertainty in cybersecurity problem-solving, offering interactive, inquiry-based learning experiences. Large language models (LLMs) have gained prominence in AI-driven QA systems, offering advanced language understanding and user engagement. However, they face challenges like hallucinations and limited domain-specific knowledge, which reduce their reliability in educational settings. To address these challenges, we propose CyberRAG, an ontology-aware retrieval-augmented generation (RAG) approach for developing a reliable and safe QA system in cybersecurity education. CyberRAG employs a two-step approach: first, it augments the domain-specific knowledge by retrieving validated cybersecurity documents from a knowledge base to enhance the relevance and accuracy of the response. Second, it mitigates hallucinations and misuse by integrating a knowledge graph ontology to validate the final answer. Experiments on publicly available cybersecurity datasets show that CyberRAG delivers accurate, reliable responses aligned with domain knowledge, demonstrating the potential of AI tools to enhance education.

Frontier models are currently developed and distributed primarily through two channels: centralized proprietary APIs or open-sourcing of pre-trained weights. We identify a third paradigm - Protocol Learning - where models are trained across decentralized networks of incentivized participants. This approach has the potential to aggregate orders of magnitude more computational resources than any single centralized entity, enabling unprecedented model scales and capabilities. However, it also introduces novel challenges: heterogeneous and unreliable nodes, malicious participants, the need for unextractable models to preserve incentives, and complex governance dynamics. To date, no systematic analysis has been conducted to assess the feasibility of Protocol Learning or the associated risks, particularly the 'No-Off Problem' arising from the inability to unilaterally halt a collectively trained model. We survey recent technical advances that suggest decentralized training may be feasible - covering emerging communication-efficient strategies and fault-tolerant methods - while highlighting critical open problems that remain. Contrary to the notion that decentralization inherently amplifies frontier risks, we argue that Protocol Learning's transparency, distributed governance, and democratized access ultimately reduce these risks compared to today's centralized regimes.