Intracortical brain-computer interfaces (iBCIs) have allowed people with tetraplegia to control a computer cursor by imagining the movement of their paralyzed arm or hand. State-of-the-art decoders deployed in human iBCIs are derived from a Kalman filter that assumes Markov dynamics on the angle of intended movement, and a unimodal dependence on intended angle for each channel of neural activity. Due to errors made in the decoding of noisy neural data, as a user attempts to move the cursor to a goal, the angle between cursor and goal positions may change rapidly. We propose a dynamic Bayesian network that includes the on-screen goal position as part of its latent state, and thus allows the person's intended angle of movement to be aggregated over a much longer history of neural activity. This multiscale model explicitly captures the relationship between instantaneous angles of motion and long-term goals, and incorporates semi-Markov dynamics for motion trajectories. We also introduce a multimodal likelihood model for recordings of neural populations which can be rapidly calibrated for clinical applications. In offline experiments with recorded neural data, we demonstrate significantly improved prediction of motion directions compared to the Kalman filter. We derive an efficient online inference algorithm, enabling a clinical trial participant with tetraplegia to control a computer cursor with neural activity in real time. The observed kinematics of cursor movement are objectively straighter and smoother than prior iBCI decoding models without loss of responsiveness.

Intracortical brain-computer interfaces (iBCIs) have allowed people with tetraplegia to control a computer cursor by imagining the movement of their paralyzed arm or hand. State-of-the-art decoders deployed in human iBCIs are derived from a Kalman filter that assumes Markov dynamics on the angle of intended movement, and a unimodal dependence on intended angle for each channel of neural activity. Due to errors made in the decoding of noisy neural data, as a user attempts to move the cursor to a goal, the angle between cursor and goal positions may change rapidly. We propose a dynamic Bayesian network that includes the on-screen goal position as part of its latent state, and thus allows the person's intended angle of movement to be aggregated over a much longer history of neural activity. This multiscale model explicitly captures the relationship between instantaneous angles of motion and long-term goals, and incorporates semi-Markov dynamics for motion trajectories. We also introduce a multimodal likelihood model for recordings of neural populations which can be rapidly calibrated for clinical applications. In offline experiments with recorded neural data, we demonstrate significantly improved prediction of motion directions compared to the Kalman filter. We derive an efficient online inference algorithm, enabling a clinical trial participant with tetraplegia to control a computer cursor with neural activity in real time. The observed kinematics of cursor movement are objectively straighter and smoother than prior iBCI decoding models without loss of responsiveness.

We also introduce a multimodal likelihood model for recordings of neural populations which can be rapidly calibrated for clinical applications.

Intracortical brain-computer interfaces (iBCIs) have allowed people with tetraplegia to control a computer cursor by imagining the movement of their paralyzed arm or hand. State-of-the-art decoders deployed in human iBCIs are derived from a Kalman filter that assumes Markov dynamics on the angle of intended movement, and a unimodal dependence on intended angle for each channel of neural activity. Due to errors made in the decoding of noisy neural data, as a user attempts to move the cursor to a goal, the angle between cursor and goal positions may change rapidly. We propose a dynamic Bayesian network that includes the on-screen goal position as part of its latent state, and thus allows the person's intended angle of movement to be aggregated over a much longer history of neural activity. This multiscale model explicitly captures the relationship between instantaneous angles of motion and long-term goals, and incorporates semi-Markov dynamics for motion trajectories. We also introduce a multimodal likelihood model for recordings of neural populations which can be rapidly calibrated for clinical applications. In offline experiments with recorded neural data, we demonstrate significantly improved prediction of motion directions compared to the Kalman filter. We derive an efficient online inference algorithm, enabling a clinical trial participant with tetraplegia to control a computer cursor with neural activity in real time. The observed kinematics of cursor movement are objectively straighter and smoother than prior iBCI decoding models without loss of responsiveness.

Individuals with tetraplegia and similar forms of paralysis suffer physically and emotionally due to a lack of autonomy. To help regain part of this autonomy, assistive robotic arms have been shown to increase living independence. However, users with paralysis pose unique challenging conditions for the control of these devices. In this article, we present the use of Diegetic Graphical User Interfaces, a novel, intuitive, and computationally inexpensive approach for gaze-controlled interfaces applied to robots. By using symbols paired with fiducial markers, interactive buttons can be defined in the real world which the user can trigger via gaze, and which can be embedded easily into the environment. We apply this system to pilot a 3-degree-of-freedom robotic arm for precision pick-and-place tasks. The interface is placed directly on the robot to allow intuitive and direct interaction, eliminating the need for context-switching between external screens, menus, and the robot. After calibration and a brief habituation period, twenty-one participants from multiple backgrounds, ages and eye-sight conditions completed the Yale-CMU-Berkeley (YCB) Block Pick and Place Protocol to benchmark the system, achieving a mean score of 13.71 out of the maximum 16.00 points. Good usability and user experience were reported (System Usability Score of 75.36) while achieving a low task workload measure (NASA-TLX of 44.76). Results show that users can employ multiple interface elements to perform actions with minimal practice and with a small cognitive load. To our knowledge, this is the first easily reconfigurable screenless system that enables robot control entirely via gaze for Cartesian robot control without the need for eye or face gestures.

Mobile manipulators in the home can provide increased autonomy to individuals with severe motor impairments, who often cannot complete activities of daily living (ADLs) without the help of a caregiver. Teleoperation of an assistive mobile manipulator could enable an individual with motor impairments to independently perform self-care and household tasks, yet limited motor function can impede one's ability to interface with a robot. In this work, we present a unique inertial-based wearable assistive interface, embedded in a familiar head-worn garment, for individuals with severe motor impairments to teleoperate and perform physical tasks with a mobile manipulator. We evaluate this wearable interface with both able-bodied (N = 16) and individuals with motor impairments (N = 2) for performing ADLs and everyday household tasks. Our results show that the wearable interface enabled participants to complete physical tasks with low error rates, high perceived ease of use, and low workload measures. Overall, this inertial-based wearable serves as a new assistive interface option for control of mobile manipulators in the home.

Robots that watch for social cues could feed people by gauging when they are ready for a mouthful. This may make it easier for people who can't feed themselves, such as those with tetraplegia, to socialise. People who can't control their legs or arms can use commercial robotic arms to help them eat.

Assistive and Wearable Robotics have the potential to support humans with different types of motor impairments to become independent and fulfil their activities of daily living successfully. The success of these robot systems, however, relies on the ability to meaningfully decode human action intentions and carry them out appropriately. Neural interfaces have been explored for use in such system with several successes, however, they tend to be invasive and require training periods in the order of months. We present a robotic system for human augmentation, capable of actuating the user's arm and fingers for them, effectively restoring the capability of reaching, grasping and manipulating objects; controlled solely through the user's eye movements. We combine wearable eye tracking, the visual context of the environment and the structural grammar of human actions to create a cognitive-level assistive robotic setup that enables the users in fulfilling activities of daily living, while conserving interpretability, and the agency of the user. The interface is worn, calibrated and ready to use within 5 minutes. Users learn to control and make successful use of the system with an additional 5 minutes of interaction. The system is tested with 5 healthy participants, showing an average success rate of $96.6\%$ on first attempt across 6 tasks.

Intracortical brain-computer interfaces (iBCIs) have allowed people with tetraplegia to control a computer cursor by imagining the movement of their paralyzed arm or hand. State-of-the-art decoders deployed in human iBCIs are derived from a Kalman filter that assumes Markov dynamics on the angle of intended movement, and a unimodal dependence on intended angle for each channel of neural activity. Due to errors made in the decoding of noisy neural data, as a user attempts to move the cursor to a goal, the angle between cursor and goal positions may change rapidly. We propose a dynamic Bayesian network that includes the on-screen goal position as part of its latent state, and thus allows the person's intended angle of movement to be aggregated over a much longer history of neural activity. This multiscale model explicitly captures the relationship between instantaneous angles of motion and long-term goals, and incorporates semi-Markov dynamics for motion trajectories.

Intracortical brain-computer interfaces (iBCIs) have allowed people with tetraplegia to control a computer cursor by imagining the movement of their paralyzed arm or hand. State-of-the-art decoders deployed in human iBCIs are derived from a Kalman filter that assumes Markov dynamics on the angle of intended movement, and a unimodal dependence on intended angle for each channel of neural activity. Due to errors made in the decoding of noisy neural data, as a user attempts to move the cursor to a goal, the angle between cursor and goal positions may change rapidly. We propose a dynamic Bayesian network that includes the on-screen goal position as part of its latent state, and thus allows the person's intended angle of movement to be aggregated over a much longer history of neural activity. This multiscale model explicitly captures the relationship between instantaneous angles of motion and long-term goals, and incorporates semi-Markov dynamics for motion trajectories. We also introduce a multimodal likelihood model for recordings of neural populations which can be rapidly calibrated for clinical applications. In offline experiments with recorded neural data, we demonstrate significantly improved prediction of motion directions compared to the Kalman filter. We derive an efficient online inference algorithm, enabling a clinical trial participant with tetraplegia to control a computer cursor with neural activity in real time. The observed kinematics of cursor movement are objectively straighter and smoother than prior iBCI decoding models without loss of responsiveness.