Electromagnetic Navigation Systems (eMNS) can be used to control a variety of multiscale devices within the human body for remote surgery. Accurate modeling of the magnetic fields generated by the electromagnets of an eMNS is crucial for the precise control of these devices. Existing methods assume a linear behavior of these systems, leading to significant modeling errors within nonlinear regions exhibited at higher magnetic fields. In this paper, we use a random forest (RF) and an artificial neural network (ANN) to model the nonlinear behavior of the magnetic fields generated by an eMNS. Both machine learning methods outperformed the state-of-the-art linear multipole electromagnet method (LMEM). The RF and the ANN model reduced the root mean squared error of the LMEM when predicting the field magnitude by around 40% and 80%, respectively, over the entire current range of the eMNS. At high current regions, especially between 30 and 35 A, the field-magnitude RMSE improvement of the ANN model over the LMEM was over 35 mT. This study demonstrates the feasibility of using machine learning methods to model an eMNS for medical applications, and its ability to account for complex nonlinear behavior at high currents. The use of machine learning thus shows promise for improving surgical procedures that use magnetic navigation.

Deep generative modeling provides a powerful pathway to overcome data scarcity in energy-related applications where experimental data are often limited, costly, or difficult to obtain. By learning the underlying probability distribution of the training dataset, deep generative models, such as the diffusion model (DM), can generate high-fidelity synthetic samples that statistically resemble the training data. Such synthetic data generation can significantly enrich the size and diversity of the available training data, and more importantly, improve the robustness of downstream machine learning models in predictive tasks. The objective of this paper is to investigate the effectiveness of DM for overcoming data scarcity in nuclear energy applications. By leveraging a public dataset on critical heat flux (CHF) that cover a wide range of commercial nuclear reactor operational conditions, we developed a DM that can generate an arbitrary amount of synthetic samples for augmenting of the CHF dataset. Since a vanilla DM can only generate samples randomly, we also developed a conditional DM capable of generating targeted CHF data under user-specified thermal-hydraulic conditions. The performance of the DM was evaluated based on their ability to capture empirical feature distributions and pair-wise correlations, as well as to maintain physical consistency. The results showed that both the DM and conditional DM can successfully generate realistic and physics-consistent CHF data. Furthermore, uncertainty quantification was performed to establish confidence in the generated data. The results demonstrated that the conditional DM is highly effective in augmenting CHF data while maintaining acceptable levels of uncertainty.

Machine learning (ML) has the potential to support and improve expert performance in monitoring the brain function of at-risk newborns. Developing accurate and reliable ML models depends on access to high-quality, annotated data, a resource in short supply. ML competitions address this need by providing researchers access to expertly annotated datasets, fostering shared learning through direct model comparisons, and leveraging the benefits of crowdsourcing diverse expertise. We compiled a retrospective dataset containing 353 hours of EEG from 102 individual newborns from a multi-centre study. The data was fully anonymised and divided into training, testing, and held-out validation datasets. EEGs were graded for the severity of abnormal background patterns. Next, we created a web-based competition platform and hosted a machine learning competition to develop ML models for classifying the severity of EEG background patterns in newborns. After the competition closed, the top 4 performing models were evaluated offline on a separate held-out validation dataset. Although a feature-based model ranked first on the testing dataset, deep learning models generalised better on the validation sets. All methods had a significant decline in validation performance compared to the testing performance. This highlights the challenges for model generalisation on unseen data, emphasising the need for held-out validation datasets in ML studies with neonatal EEG. The study underscores the importance of training ML models on large and diverse datasets to ensure robust generalisation. The competition's outcome demonstrates the potential for open-access data and collaborative ML development to foster a collaborative research environment and expedite the development of clinical decision-support tools for neonatal neuromonitoring.

Diffusion models have emerged as powerful generative frameworks with widespread applications across machine learning and artificial intelligence systems. While current research has predominantly focused on linear diffusions, these approaches can face significant challenges when modeling a conditional distribution, $P(Y|X=x)$, when $P(X=x)$ is small. In these regions, few samples, if any, are available for training, thus modeling the corresponding conditional density may be difficult. Recognizing this, we show it is possible to adapt the data representation and forward scheme so that the sample complexity of learning a score-based generative model is small in low probability regions of the conditioning space. Drawing inspiration from conditional extreme value theory we characterize this method precisely in the special case in the tail regions of the conditioning variable, $X$. We show how diffusion with a data-driven choice of nonlinear drift term is best suited to model tail events under an appropriate representation of the data. Through empirical validation on two synthetic datasets and a real-world financial dataset, we demonstrate that our tail-adaptive approach significantly outperforms standard diffusion models in accurately capturing response distributions at the extreme tail conditions.

Deep neural networks (DNNs) have demonstrated remarkable success in medical imaging, yet their real-world deployment remains challenging due to spurious correlations, where models can learn non-clinical features instead of meaningful medical patterns. Existing medical imaging datasets are not designed to systematically study this issue, largely due to restrictive licensing and limited supplementary patient data. To address this gap, we introduce SpurBreast, a curated breast MRI dataset that intentionally incorporates spurious correlations to evaluate their impact on model performance. Analyzing over 100 features involving patient, device, and imaging protocol, we identify two dominant spurious signals: magnetic field strength (a global feature influencing the entire image) and image orientation (a local feature affecting spatial alignment). Through controlled dataset splits, we demonstrate that DNNs can exploit these non-clinical signals, achieving high validation accuracy while failing to generalize to unbiased test data. Alongside these two datasets containing spurious correlations, we also provide benchmark datasets without spurious correlations, allowing researchers to systematically investigate clinically relevant and irrelevant features, uncertainty estimation, adversarial robustness, and generalization strategies.

Life expectancy is a fundamental indicator of population health and socio-economic well-being, yet accurately forecasting it remains challenging due to the interplay of demographic, environmental, and healthcare factors. Thi s study evaluates three machine learning models--Linear Regression (LR), Regression Decision Tree (RDT), and Random Forest (RF), using a real -world da-taset drawn from World Health Organization (WHO) and United N ations (UN) sources. After extensive preprocessing to address missing v alues and inconsistencies, each model's performance was assessed with R, Mean Absolute Error (MAE), and Root Mean Squared Error (RMSE). Results show tha t RF achieves the highest predictive accuracy (R = 0.9423), significantly outperforming LR and RDT. Interpretability was prioritized through p -values for LR and feature - importance metrics for the tree -based models, revealing immunization rates (diphtheria, measles) and demographic attributes (HIV/AIDS, adult mortality) as critical drivers of life-expectancy predictions. These insights underscore the synergy between ensemble methods and transparency in addressing public -health challenges. Future research should explore advanced imputation strategies, alternative algorithms (e.g., neural networks), and updated data to further refine predictive accuracy and support evidence-based policymaking in global health contexts.

Understanding urban human mobility patterns at various spatial levels is essential for social science. This study presents a machine learning framework to downscale origin-destination (OD) taxi trips flows in New York City from a larger spatial unit to a smaller spatial unit. First, correlations between OD trips and demographic, socioeconomic, and commuting characteristics are developed using four models: Linear Regression (LR), Random Forest (RF), Support Vector Machine (SVM), and Neural Networks (NN). Second, a perturbation-based sensitivity analysis is applied to interpret variable importance for nonlinear models. The results show that the linear regression model failed to capture the complex variable interactions. While NN performs best with the training and testing datasets, SVM shows the best generalization ability in downscaling performance. The methodology presented in this study provides both analytical advancement and practical applications to improve transportation services and urban development.

Modeling limit order books (LOBs) dynamics is a fundamental problem in market microstructure research. In particular, generating high-dimensional volume snapshots with strong temporal and liquidity-dependent patterns remains a challenging task, despite recent work exploring the application of Generative Adversarial Networks to LOBs. In this work, we propose a conditional \textbf{Diff}usion model for the generation of future LOB \textbf{Volume} snapshots (\textbf{DiffVolume}). We evaluate our model across three axes: (1) \textit{Realism}, where we show that DiffVolume, conditioned on past volume history and time of day, better reproduces statistical properties such as marginal distribution, spatial correlation, and autocorrelation decay; (2) \textit{Counterfactual generation}, allowing for controllable generation under hypothetical liquidity scenarios by additionally conditioning on a target future liquidity profile; and (3) \textit{Downstream prediction}, where we show that the synthetic counterfactual data from our model improves the performance of future liquidity forecasting models. Together, these results suggest that DiffVolume provides a powerful and flexible framework for realistic and controllable LOB volume generation.