Interest in generative Electrocardiogram-Language Models (ELMs) is growing, as they can produce textual responses conditioned on ECG signals and textual queries. Unlike traditional classifiers that output label probabilities, ELMs are more versatile, supporting domain-specific tasks (e.g., waveform analysis, diagnosis, prognosis) as well as general tasks (e.g., open-ended questions, dialogue). Retrieval-Augmented Generation (RAG), widely used in Large Language Models (LLMs) to ground LLM outputs in retrieved knowledge, helps reduce hallucinations and improve natural language generation (NLG). However, despite its promise, no open-source implementation or systematic study of RAG pipeline design for ELMs currently exists. To address this gap, we present the first open-source RAG pipeline for ELMs, along with baselines and ablation studies for NLG. Experiments on three public datasets show that ELMs with RAG consistently improves performance over non-RAG baselines and highlights key ELM design considerations. Our code is available at: https://github.com/willxxy/ECG-Bench.

A novel methodology for short-term energy forecasting using an Extreme Learning Machine ($\mathtt{ELM}$) is proposed. Using six years of hourly data collected in Corsica (France) from multiple energy sources (solar, wind, hydro, thermal, bioenergy, and imported electricity), our approach predicts both individual energy outputs and total production (including imports, which closely follow energy demand, modulo losses) through a Multi-Input Multi-Output ($\mathtt{MIMO}$) architecture. To address non-stationarity and seasonal variability, sliding window techniques and cyclic time encoding are incorporated, enabling dynamic adaptation to fluctuations. The $\mathtt{ELM}$ model significantly outperforms persistence-based forecasting, particularly for solar and thermal energy, achieving an $\mathtt{nRMSE}$ of $17.9\%$ and $5.1\%$, respectively, with $\mathtt{R^2} > 0.98$ (1-hour horizon). The model maintains high accuracy up to five hours ahead, beyond which renewable energy sources become increasingly volatile. While $\mathtt{MIMO}$ provides marginal gains over Single-Input Single-Output ($\mathtt{SISO}$) architectures and offers key advantages over deep learning methods such as $\mathtt{LSTM}$, it provides a closed-form solution with lower computational demands, making it well-suited for real-time applications, including online learning. Beyond predictive accuracy, the proposed methodology is adaptable to various contexts and datasets, as it can be tuned to local constraints such as resource availability, grid characteristics, and market structures.

Increasing resolution and coverage of astrophysical and climate data necessitates increasingly sophisticated models, often pushing the limits of computational feasibility. While emulation methods can reduce calculation costs, the neural architectures typically used--optimised via gradient descent--are themselves computationally expensive to train, particularly in terms of data generation requirements. This paper investigates the utility of the Extreme Learning Machine (ELM) as a lightweight, non-gradient-based machine learning algorithm for accelerating complex physical models. We evaluate ELM surrogate models in two test cases with different data structures: (i) sequentially-structured data, and (ii) image-structured data. For test case (i), where the number of samples $N$ >> the dimensionality of input data $d$, ELMs achieve remarkable efficiency, offering a 100,000$\times$ faster training time and a 40$\times$ faster prediction speed compared to a Bi-Directional Recurrent Neural Network (BIRNN), whilst improving upon BIRNN test performance. For test case (ii), characterised by $d >> N$ and image-based inputs, a single ELM was insufficient, but an ensemble of 50 individual ELM predictors achieves comparable accuracy to a benchmark Convolutional Neural Network (CNN), with a 16.4$\times$ reduction in training time, though costing a 6.9$\times$ increase in prediction time. We find different sample efficiency characteristics between the test cases: in test case (i) individual ELMs demonstrate superior sample efficiency, requiring only 0.28% of the training dataset compared to the benchmark BIRNN, while in test case (ii) the ensemble approach requires 78% of the data used by the CNN to achieve comparable results--representing a trade-off between sample efficiency and model complexity.

Recent advances have increasingly applied large language models (LLMs) to electrocardiogram (ECG) interpretation, giving rise to Electrocardiogram-Language Models (ELMs). Conditioned on an ECG and a textual query, an ELM autoregressively generates a free-form textual response. Unlike traditional classification-based systems, ELMs emulate expert cardiac electrophysiologists by issuing diagnoses, analyzing waveform morphology, identifying contributing factors, and proposing patient-specific action plans. To realize this potential, researchers are curating instruction-tuning datasets that pair ECGs with textual dialogues and are training ELMs on these resources. Yet before scaling ELMs further, there is a fundamental question yet to be explored: What is the most effective ECG input representation? In recent works, three candidate representations have emerged-raw time-series signals, rendered images, and discretized symbolic sequences. We present the first comprehensive benchmark of these modalities across 6 public datasets and 5 evaluation metrics. We find symbolic representations achieve the greatest number of statistically significant wins over both signal and image inputs. We further ablate the LLM backbone, ECG duration, and token budget, and we evaluate robustness to signal perturbations. We hope that our findings offer clear guidance for selecting input representations when developing the next generation of ELMs.

Population-based cancer registries (PBCRs) face a significant bottleneck in manually extracting data from unstructured pathology reports, a process crucial for tasks like tumor group assignment, which can consume 900 person-hours for approximately 100,000 reports. To address this, we introduce ELM (Ensemble of Language Models), a novel ensemble-based approach leveraging both small language models (SLMs) and large language models (LLMs). ELM utilizes six fine-tuned SLMs, where three SLMs use the top part of the pathology report and three SLMs use the bottom part. This is done to maximize report coverage. ELM requires five-out-of-six agreement for a tumor group classification. Disagreements are arbitrated by an LLM with a carefully curated prompt. Our evaluation across nineteen tumor groups demonstrates ELM achieves an average precision and recall of 0.94, outperforming single-model and ensemble-without-LLM approaches. Deployed at the British Columbia Cancer Registry, ELM demonstrates how LLMs can be successfully applied in a PBCR setting to achieve state-of-the-art results and significantly enhance operational efficiencies, saving hundreds of person-hours annually.

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention mechanism architecture on model performance is not well-documented for biomedical imagery. In this work, we compare different methods and implementations of MIL, including deep learning variants. We introduce a new method using higher-dimensional feature spaces for deep MIL. We also develop a novel algorithm for whole-slide image classification where extreme machine learning is combined with attention-based MIL to improve sensitivity and reduce training complexity. We apply our algorithms to the problem of detecting circulating rare cells (CRCs), such as erythroblasts, in peripheral blood. Our results indicate that nonlinearities play a key role in the classification, as removing them leads to a sharp decrease in stability in addition to a decrease in average area under the curve (AUC) of over 4%. We also demonstrate a considerable increase in robustness of the model with improvements of over 10% in average AUC when higher-dimensional feature spaces are leveraged. In addition, we show that extreme learning machines can offer clear improvements in terms of training efficiency by reducing the number of trained parameters by a factor of 5 whilst still maintaining the average AUC to within 1.5% of the deep MIL model. Finally, we discuss options of enriching the classical computing framework with quantum algorithms in the future. This work can thus help pave the way towards more accurate and efficient single-cell diagnostics, one of the building blocks of precision medicine.

Clearsky models are widely used in solar energy for many applications such as quality control, resource assessment, satellite-base irradiance estimation and forecasting. However, their use in forecasting and nowcasting is associated with a number of challenges. Synchronization errors, reliance on the Clearsky index (ratio of the global horizontal irradiance to its cloud-free counterpart) and high sensitivity of the clearsky model to errors in aerosol optical depth at low solar elevation limit their added value in real-time applications. This paper explores the feasibility of short-term forecasting without relying on a clearsky model. We propose a Clearsky-Free forecasting approach using Extreme Learning Machine (ELM) models. ELM learns daily periodicity and local variability directly from raw Global Horizontal Irradiance (GHI) data. It eliminates the need for Clearsky normalization, simplifying the forecasting process and improving scalability. Our approach is a non-linear adaptative statistical method that implicitely learns the irradiance in cloud-free conditions removing the need for an clear-sky model and the related operational issues. Deterministic and probabilistic results are compared to traditional benchmarks, including ARMA with McClear-generated Clearsky data and quantile regression for probabilistic forecasts. ELM matches or outperforms these methods, providing accurate predictions and robust uncertainty quantification. This approach offers a simple, efficient solution for real-time solar forecasting. By overcoming the stationarization process limitations based on usual multiplicative scheme Clearsky models, it provides a flexible and reliable framework for modern energy systems.

Utilizing machine learning techniques has always required choosing hyperparameters. This is true whether one uses a classical technique such as a KNN or very modern neural networks such as Deep Learning. Though in many applications, hyperparameters are chosen by hand, automated methods have become increasingly more common. These automated methods have become collectively known as automated machine learning, or AutoML. Several automated selection algorithms have shown similar or improved performance over state-of-the-art methods. This breakthrough has led to the development of cloud-based services like Google AutoML, which is based on Deep Learning and is widely considered to be the industry leader in AutoML services. Extreme Learning Machines (ELMs) use a fundamentally different type of neural architecture, producing better results at a significantly discounted computational cost. We benchmark the Extreme AutoML technology against Google's AutoML using several popular classification data sets from the University of California at Irvine's (UCI) repository, and several other data sets, observing significant advantages for Extreme AutoML in accuracy, Jaccard Indices, the variance of Jaccard Indices across classes (i.e. class variance) and training times.

The Extreme Learning Machine (ELM) is a growing statistical technique widely applied to regression problems. In essence, ELMs are single-layer neural networks where the hidden layer weights are randomly sampled from a specific distribution, while the output layer weights are learned from the data. Two of the key challenges with this approach are the architecture design, specifically determining the optimal number of neurons in the hidden layer, and the method's sensitivity to the random initialization of hidden layer weights. This paper introduces a new and enhanced learning algorithm for regression tasks, the Effective Non-Random ELM (ENR-ELM), which simplifies the architecture design and eliminates the need for random hidden layer weight selection. The proposed method incorporates concepts from signal processing, such as basis functions and projections, into the ELM framework. We introduce two versions of the ENR-ELM: the approximated ENR-ELM and the incremental ENR-ELM. Experimental results on both synthetic and real datasets demonstrate that our method overcomes the problems of traditional ELM while maintaining comparable predictive performance.

Contrastive decoding (CD) (Li et al., 2023) improves the next-token distribution of a large expert language model (LM) using a small amateur LM. Although CD is applied to various LMs and domains to enhance open-ended text generation, it is still unclear why CD often works well, when it could fail, and how we can make it better. To deepen our understanding of CD, we first theoretically prove that CD could be viewed as linearly extrapolating the next-token logits from a huge and hypothetical LM. We also highlight that the linear extrapolation could make CD unable to output the most obvious answers that have already been assigned high probabilities by the amateur LM. To overcome CD's limitation, we propose a new unsupervised decoding method called $\mathbf{A}$symptotic $\mathbf{P}$robability $\mathbf{D}$ecoding (APD). APD explicitly extrapolates the probability curves from the LMs of different sizes to infer the asymptotic probabilities from an infinitely large LM without inducing more inference costs than CD. In FactualityPrompts, an open-ended text generation benchmark, sampling using APD significantly boosts factuality in comparison to the CD sampling and its variants, and achieves state-of-the-art results for Pythia 6.9B and OPT 6.7B. Furthermore, in five commonsense QA datasets, APD is often significantly better than CD and achieves a similar effect of using a larger LLM. For example, the perplexity of APD on top of Pythia 6.9B is even lower than the perplexity of Pythia 12B in CommonsenseQA and LAMBADA.