Efficient quantum state preparation remains a central challenge in first-principles quantum simulations of dynamics in quantum field theories, where the Hilbert space is intrinsically infinite-dimensional. Here, we introduce a large language model (LLM)-assisted framework for quantum-circuit design that systematically scales state-preparation circuits to large lattice volumes. Applied to a 1+1d XY spin chain, the LLM autonomously discovers a compact 4-parameter circuit that captures boundary-induced symmetry breaking with sub-percent energy deviation, enabling successful validation on the \texttt{Zuchongzhi} quantum processor. Guided by this insight, we extend the framework to 2+1d quantum field theories, where scalable variational ansätze have remained elusive. For a scalar field theory, the search yields a symmetry-preserving, 3-parameter shallow-depth ansatz whose optimized parameters converge to size-independent constants for lattices $n \ge 4$, providing, to our knowledge, the first scalable ansatz for this class of 2+1d models. Our results establish a practical route toward AI-assisted, human-guided discovery in quantum simulation.

CNOT gates are fundamental to quantum computing, as they facilitate entanglement, a crucial resource for quantum algorithms. Certain classes of quantum circuits are constructed exclusively from CNOT gates. Given their widespread use, it is imperative to minimise the number of CNOT gates employed. This problem, known as CNOT minimisation, remains an open challenge, with its computational complexity yet to be fully characterised. In this work, we introduce a novel reinforcement learning approach to address this task. Instead of training multiple reinforcement learning agents for different circuit sizes, we use a single agent up to a fixed size $m$. Matrices of sizes different from m are preprocessed using either embedding or Gaussian striping. To assess the efficacy of our approach, we trained an agent with m = 8, and evaluated it on matrices of size n that range from 3 to 15. The results we obtained show that our method overperforms the state-of-the-art algorithm as the value of n increases.

Clifford circuit optimization is an important step in the quantum compilation pipeline. Major compilers employ heuristic approaches. While they are fast, their results are often suboptimal. Minimization of noisy gates, like 2-qubit CNOT gates, is crucial for practical computing. Exact approaches have been proposed to fill the gap left by heuristic approaches. Among these are SAT based approaches that optimize gate count or depth, but they suffer from scalability issues. Further, they do not guarantee optimality on more important metrics like CNOT count or CNOT depth. A recent work proposed an exhaustive search only on Clifford circuits in a certain normal form to guarantee CNOT count optimality. But an exhaustive approach cannot scale beyond 6 qubits. In this paper, we incorporate search restricted to Clifford normal forms in a SAT encoding to guarantee CNOT count optimality. By allowing parallel plans, we propose a second SAT encoding that optimizes CNOT depth. By taking advantage of flexibility in SAT based approaches, we also handle connectivity restrictions in hardware platforms, and allow for qubit relabeling. We have implemented the above encodings and variations in our open source tool Q-Synth. In experiments, our encodings significantly outperform existing SAT approaches on random Clifford circuits. We consider practical VQE and Feynman benchmarks to compare with TKET and Qiskit compilers. In all-to-all connectivity, we observe reductions up to 32.1% in CNOT count and 48.1% in CNOT depth. Overall, we observe better results than TKET in the CNOT count and depth. We also experiment with connectivity restrictions of major quantum platforms. Compared to Qiskit, we observe up to 30.3% CNOT count and 35.9% CNOT depth further reduction.

In this work, scalable quantum neural networks are introduced to approximate unitary evolutions through the Standard Recursive Block Basis (SRBB) and, subsequently, redesigned with a reduced number of CNOTs. This algebraic approach to the problem of unitary synthesis exploits Lie algebras and their topological features to obtain scalable parameterizations of unitary operators. First, the recursive algorithm that builds the SRBB is presented, framed in the original scalability scheme already known to the literature only from a theoretical point of view. Unexpectedly, 2-qubit systems emerge as a special case outside this scheme. Furthermore, an algorithm to reduce the number of CNOTs is proposed, thus deriving a new implementable scaling scheme that requires one single layer of approximation. From the mathematical algorithm, the scalable CNOT-reduced quantum neural network is implemented and its performance is assessed with a variety of different unitary matrices, both sparse and dense, up to 6 qubits via the PennyLane library. The effectiveness of the approximation is measured with different metrics in relation to two optimizers: a gradient-based method and the Nelder-Mead method. The approximate SRBB-based synthesis algorithm with CNOT-reduction is also tested on real hardware and compared with other valid approximation and decomposition methods available in the literature.

CNOT optimization plays a significant role in noise reduction for Quantum Circuits. Several heuristic and exact approaches exist for CNOT optimization. In this paper, we investigate more complicated variations of optimal synthesis by allowing qubit permutations and handling layout restrictions. We encode such problems into Planning, SAT, and QBF. We provide optimization for both CNOT gate count and circuit depth. For experimental evaluation, we consider standard T-gate optimized benchmarks and optimize CNOT sub-circuits. We show that allowing qubit permutations can further reduce up to 56% in CNOT count and 46% in circuit depth. In the case of optimally mapped circuits under layout restrictions, we observe a reduction up to 17% CNOT count and 19% CNOT depth.

In recent years, Quantum Machine Learning (QML) has increasingly captured the interest of researchers. Among the components in this domain, activation functions hold a fundamental and indispensable role. Our research focuses on the development of activation functions quantum circuits for integration into fault-tolerant quantum computing architectures, with an emphasis on minimizing $T$-depth. Specifically, we present novel implementations of ReLU and leaky ReLU activation functions, achieving constant $T$-depths of 4 and 8, respectively. Leveraging quantum lookup tables, we extend our exploration to other activation functions such as the sigmoid. This approach enables us to customize precision and $T$-depth by adjusting the number of qubits, making our results more adaptable to various application scenarios. This study represents a significant advancement towards enhancing the practicality and application of quantum machine learning.

Layout synthesis is mapping a quantum circuit to a quantum processor. SWAP gate insertions are needed for scheduling 2-qubit gates only on connected physical qubits. With the ever-increasing number of qubits in NISQ processors, scalable layout synthesis is of utmost importance. With large optimality gaps observed in heuristic approaches, scalable exact methods are needed. While recent exact and near-optimal approaches scale to moderate circuits, large deep circuits are still out of scope. In this work, we propose a SAT encoding based on parallel plans that apply 1 SWAP and a group of CNOTs at each time step. Using domain-specific information, we maintain optimality in parallel plans while scaling to large and deep circuits. From our results, we show the scalability of our approach which significantly outperforms leading exact and near-optimal approaches (up to 100x). For the first time, we can optimally map several 8, 14, and 16 qubit circuits onto 54, 80, and 127 qubit platforms with up to 17 SWAPs. While adding optimal SWAPs, we also report near-optimal depth in our mapped circuits.

The potential impact of quantum machine learning algorithms on industrial applications remains an exciting open question. Conventional methods for encoding classical data into quantum computers are not only too costly for a potential quantum advantage in the algorithms but also severely limit the scale of feasible experiments on current hardware. Therefore, recent works, despite claiming the near-term suitability of their algorithms, do not provide experimental benchmarking on standard machine learning datasets. We attempt to solve the data encoding problem by improving a recently proposed variational algorithm [1] that approximately prepares the encoded data, using asymptotically shallow circuits that fit the native gate set and topology of currently available quantum computers. We apply the improved algorithm to encode the Fashion-MNIST dataset [2], which can be directly used in future empirical studies of quantum machine learning algorithms. We deploy simple quantum variational classifiers trained on the encoded dataset on a current quantum computer ibmq-kolkata [3] and achieve moderate accuracies, providing a proof of concept for the near-term usability of our data encoding method.

Extracting information efficiently from quantum systems is a major component of quantum information processing tasks. Randomized measurements, or classical shadows, enable predicting many properties of arbitrary quantum states using few measurements. While random single qubit measurements are experimentally friendly and suitable for learning low-weight Pauli observables, they perform poorly for nonlocal observables. Prepending a shallow random quantum circuit before measurements maintains this experimental friendliness, but also has favorable sample complexities for observables beyond low-weight Paulis, including high-weight Paulis and global low-rank properties such as fidelity. However, in realistic scenarios, quantum noise accumulated with each additional layer of the shallow circuit biases the results. To address these challenges, we propose the robust shallow shadows protocol. Our protocol uses Bayesian inference to learn the experimentally relevant noise model and mitigate it in postprocessing. This mitigation introduces a bias-variance trade-off: correcting for noise-induced bias comes at the cost of a larger estimator variance. Despite this increased variance, as we demonstrate on a superconducting quantum processor, our protocol correctly recovers state properties such as expectation values, fidelity, and entanglement entropy, while maintaining a lower sample complexity compared to the random single qubit measurement scheme. We also theoretically analyze the effects of noise on sample complexity and show how the optimal choice of the shallow shadow depth varies with noise strength. This combined theoretical and experimental analysis positions the robust shallow shadow protocol as a scalable, robust, and sample-efficient protocol for characterizing quantum states on current quantum computing platforms.

Feature selection is critical in machine learning to reduce dimensionality and improve model accuracy and efficiency. The exponential growth in feature space dimensionality for modern datasets directly results in ambiguous samples and redundant features, which can severely degrade classification accuracy. Quantum machine learning offers potential advantages for addressing this challenge. In this paper, we propose a novel method, quantum support vector machine feature selection (QSVMF), integrating quantum support vector machines with multi-objective genetic algorithm. QSVMF optimizes multiple simultaneous objectives: maximizing classification accuracy, minimizing selected features and quantum circuit costs, and reducing feature covariance. We apply QSVMF for feature selection on a breast cancer dataset, comparing the performance of QSVMF against classical approaches with the selected features. Experimental results show that QSVMF achieves superior performance. Furthermore, The Pareto front solutions of QSVMF enable analysis of accuracy versus feature set size trade-offs, identifying extremely sparse yet accurate feature subsets. We contextualize the biological relevance of the selected features in terms of known breast cancer biomarkers. This work highlights the potential of quantum-based feature selection to enhance machine learning efficiency and performance on complex real-world data.