The rapid growth of the financial sector and the rising focus on Environmental, Social, and Governance (ESG) considerations highlight the need for advanced NLP tools. However, open-source LLMs proficient in both finance and ESG domains remain scarce. To address this gap, we introduce SusGen-30K, a category-balanced dataset comprising seven financial NLP tasks and ESG report generation, and propose TCFD-Bench, a benchmark for evaluating sustainability report generation. Leveraging this dataset, we developed SusGen-GPT, a suite of models achieving state-of-the-art performance across six adapted and two off-the-shelf tasks, trailing GPT-4 by only 2% despite using 7-8B parameters compared to GPT-4's 1,700B. Based on this, we propose the SusGen system, integrated with Retrieval-Augmented Generation (RAG), to assist in sustainability report generation. This work demonstrates the efficiency of our approach, advancing research in finance and ESG.

Team Coordination on Graphs with Risky Edges (\textsc{tcgre}) is a recently proposed problem, in which robots find paths to their goals while considering possible coordination to reduce overall team cost. However, \textsc{tcgre} assumes that the \emph{entire} environment is available to a \emph{homogeneous} robot team with \emph{ubiquitous} communication. In this paper, we study an extended version of \textsc{tcgre}, called \textsc{hpr-tcgre}, with three relaxations: Heterogeneous robots, Partial observability, and Realistic communication. To this end, we form a new combinatorial optimization problem on top of \textsc{tcgre}. After analysis, we divide it into two sub-problems, one for robots moving individually, another for robots in groups, depending on their communication availability. Then, we develop an algorithm that exploits real-time partial maps to solve local shortest path(s) problems, with a A*-like sub-goal(s) assignment mechanism that explores potential coordination opportunities for global interests. Extensive experiments indicate that our algorithm is able to produce team coordination behaviors in order to reduce overall cost even with our three relaxations.

Recently, there has been a revived interest in system neuroscience causation models due to their unique capability to unravel complex relationships in multi-scale brain networks. In this paper, our goal is to verify the feasibility and effectiveness of using a causality-based approach for fMRI fingerprinting. Specifically, we propose an innovative method that utilizes the causal dynamics activities of the brain to identify the unique cognitive patterns of individuals (e.g., subject fingerprint) and fMRI tasks (e.g., task fingerprint). The key novelty of our approach stems from the development of a two-timescale linear state-space model to extract 'spatio-temporal' (aka causal) signatures from an individual's fMRI time series data. To the best of our knowledge, we pioneer and subsequently quantify, in this paper, the concept of 'causal fingerprint.' Our method is well-separated from other fingerprint studies as we quantify fingerprints from a cause-and-effect perspective, which are then incorporated with a modal decomposition and projection method to perform subject identification and a GNN-based (Graph Neural Network) model to perform task identification. Finally, we show that the experimental results and comparisons with non-causality-based methods demonstrate the effectiveness of the proposed methods. We visualize the obtained causal signatures and discuss their biological relevance in light of the existing understanding of brain functionalities. Collectively, our work paves the way for further studies on causal fingerprints with potential applications in both healthy controls and neurodegenerative diseases.

Drug-target relationships may now be predicted computationally using bioinformatics data, which is a valuable tool for understanding pharmacological effects, enhancing drug development efficiency, and advancing related research. A number of structure-based, ligand-based and network-based approaches have now emerged. Furthermore, the integration of graph attention networks with intricate drug target studies is an application area of growing interest. In our work, we formulate a model called MKDTI by extracting kernel information from various layer embeddings of a graph attention network. This combination improves the prediction ability with respect to novel drug-target relationships. We first build a drug-target heterogeneous network using heterogeneous data of drugs and targets, and then use a self-enhanced multi-head graph attention network to extract potential features in each layer. Next, we utilize embeddings of each layer to computationally extract kernel matrices and fuse multiple kernel matrices. Finally, we use a Dual Laplacian Regularized Least Squares framework to forecast novel drug-target entity connections. This prediction can be facilitated by integrating the kernel matrix associated with the drug-target. We measured our model's efficacy using AUPR and AUC. Compared to the benchmark algorithms, our model outperforms them in the prediction outcomes. In addition, we conducted an experiment on kernel selection. The results show that the multi-kernel fusion approach combined with the kernel matrix generated by the graph attention network provides complementary insights into the model. The fusion of this information helps to enhance the accuracy of the predictions.

This paper aims to solve the coordination of a team of robots traversing a route in the presence of adversaries with random positions. Our goal is to minimize the overall cost of the team, which is determined by (i) the accumulated risk when robots stay in adversary-impacted zones and (ii) the mission completion time. During traversal, robots can reduce their speed and act as a `guard' (the slower, the better), which will decrease the risks certain adversary incurs. This leads to a trade-off between the robots' guarding behaviors and their travel speeds. The formulated problem is highly non-convex and cannot be efficiently solved by existing algorithms. Our approach includes a theoretical analysis of the robots' behaviors for the single-adversary case. As the scale of the problem expands, solving the optimal solution using optimization approaches is challenging, therefore, we employ reinforcement learning techniques by developing new encoding and policy-generating methods. Simulations demonstrate that our learning methods can efficiently produce team coordination behaviors. We discuss the reasoning behind these behaviors and explain why they reduce the overall team cost.

Multi-hop question answering (MHQA) requires a model to retrieve and integrate information from multiple passages to answer a complex question. Recent systems leverage the power of large language models and integrate evidence retrieval with reasoning prompts (e.g., chain-of-thought reasoning) for the MHQA task. However, the complexities in the question types (bridge v.s. comparison questions) and the reasoning types (sequential v.s. parallel reasonings) require more novel and fine-grained prompting methods to enhance the performance of MHQA under the zero-shot setting. In this paper, we propose STOC-TOT, a stochastic tree-of-thought reasoning prompting method with constrained decoding for MHQA and conduct a detailed comparison with other reasoning prompts on different question types and reasoning types. Specifically, we construct a tree-like reasoning structure by prompting the model to break down the original question into smaller sub-questions to form different reasoning paths. In addition, we prompt the model to provide a probability estimation for each reasoning path at each reasoning step. At answer time, we conduct constrained decoding on the model to generate more grounded answers and reduce hallucination. Experiments comparing STOC-TOT with two MHQA datasets and five large language models showed that our framework outperforms other reasoning prompts by a significant margin.

Databases are fundamental to contemporary information systems, yet traditional rule-based configuration methods struggle to manage the complexity of real-world applications with hundreds of tunable parameters. Deep reinforcement learning (DRL), which combines perception and decision-making, presents a potential solution for intelligent database configuration tuning. However, due to black-box property of RL-based method, the generated database tuning strategies still face the urgent problem of lack explainability. Besides, the redundant parameters in large scale database always make the strategy learning become unstable. This paper proposes KnobTree, an interpertable framework designed for the optimization of database parameter configuration. In this framework, an interpertable database tuning algorithm based on RL-based differentatial tree is proposed, which building a transparent tree-based model to generate explainable database tuning strategies. To address the problem of large-scale parameters, We also introduce a explainable method for parameter importance assessment, by utilizing Shapley Values to identify parameters that have significant impacts on database performance. Experiments conducted on MySQL and Gbase8s databases have verified exceptional transparency and interpretability of the KnobTree model. The good property makes generated strategies can offer practical guidance to algorithm designers and database administrators. Moreover, our approach also slightly outperforms the existing RL-based tuning algorithms in aspects such as throughput, latency, and processing time.

Pathogen identification is pivotal in diagnosing, treating, and preventing diseases, crucial for controlling infections and safeguarding public health. Traditional alignment-based methods, though widely used, are computationally intense and reliant on extensive reference databases, often failing to detect novel pathogens due to their low sensitivity and specificity. Similarly, conventional machine learning techniques, while promising, require large annotated datasets and extensive feature engineering and are prone to overfitting. Addressing these challenges, we introduce PathoLM, a cutting-edge pathogen language model optimized for the identification of pathogenicity in bacterial and viral sequences. Leveraging the strengths of pre-trained DNA models such as the Nucleotide Transformer, PathoLM requires minimal data for fine-tuning, thereby enhancing pathogen detection capabilities. It effectively captures a broader genomic context, significantly improving the identification of novel and divergent pathogens. We developed a comprehensive data set comprising approximately 30 species of viruses and bacteria, including ESKAPEE pathogens, seven notably virulent bacterial strains resistant to antibiotics. Additionally, we curated a species classification dataset centered specifically on the ESKAPEE group. In comparative assessments, PathoLM dramatically outperforms existing models like DciPatho, demonstrating robust zero-shot and few-shot capabilities. Furthermore, we expanded PathoLM-Sp for ESKAPEE species classification, where it showed superior performance compared to other advanced deep learning methods, despite the complexities of the task.

We used a dictionary built from biomedical terminology extracted from various sources such as DrugBank, MedDRA, MedlinePlus, TCMGeneDIT, to tag more than 8 million Instagram posts by users who have mentioned an epilepsy-relevant drug at least once, between 2010 and early 2016. A random sample of 1,771 posts with 2,947 term matches was evaluated by human annotators to identify false-positives. OpenAI's GPT series models were compared against human annotation. Frequent terms with a high false-positive rate were removed from the dictionary. Analysis of the estimated false-positive rates of the annotated terms revealed 8 ambiguous terms (plus synonyms) used in Instagram posts, which were removed from the original dictionary. To study the effect of removing those terms, we constructed knowledge networks using the refined and the original dictionaries and performed an eigenvector-centrality analysis on both networks. We show that the refined dictionary thus produced leads to a significantly different rank of important terms, as measured by their eigenvector-centrality of the knowledge networks. Furthermore, the most important terms obtained after refinement are of greater medical relevance. In addition, we show that OpenAI's GPT series models fare worse than human annotators in this task.

This paper studies the problem of Cooperative Localization (CL) for multi-robot systems, where a group of mobile robots jointly localize themselves by using measurements from onboard sensors and shared information from other robots. We propose a novel distributed invariant Kalman Filter (DInEKF) based on the Lie group theory, to solve the CL problem in a 3-D environment. Unlike the standard EKF which computes the Jacobians based on the linearization at the state estimate, DInEKF defines the robots' motion model on matrix Lie groups and offers the advantage of state estimate-independent Jacobians. This significantly improves the consistency of the estimator. Moreover, the proposed algorithm is fully distributed, relying solely on each robot's ego-motion measurements and information received from its one-hop communication neighbors. The effectiveness of the proposed algorithm is validated in both Monte-Carlo simulations and real-world experiments. The results show that the proposed DInEKF outperforms the standard distributed EKF in terms of both accuracy and consistency.