Multi-class segmentation of the aorta in computed tomography angiography (CTA) scans is essential for diagnosing and planning complex endovascular treatments for patients with aortic dissections. However, existing methods reduce aortic segmentation to a binary problem, limiting their ability to measure diameters across different branches and zones. Furthermore, no open-source dataset is currently available to support the development of multi-class aortic segmentation methods. To address this gap, we organized the AortaSeg24 MICCAI Challenge, introducing the first dataset of 100 CTA volumes annotated for 23 clinically relevant aortic branches and zones. This dataset was designed to facilitate both model development and validation. The challenge attracted 121 teams worldwide, with participants leveraging state-of-the-art frameworks such as nnU-Net and exploring novel techniques, including cascaded models, data augmentation strategies, and custom loss functions. We evaluated the submitted algorithms using the Dice Similarity Coefficient (DSC) and Normalized Surface Distance (NSD), highlighting the approaches adopted by the top five performing teams. This paper presents the challenge design, dataset details, evaluation metrics, and an in-depth analysis of the top-performing algorithms. The annotated dataset, evaluation code, and implementations of the leading methods are publicly available to support further research. All resources can be accessed at https://aortaseg24.grand-challenge.org.

The embedded topic model (ETM) is a widely used approach that assumes the sampled document-topic distribution conforms to the logistic normal distribution for easier optimization. However, this assumption oversimplifies the real document-topic distribution, limiting the model's performance. In response, we propose a novel method that introduces the diffusion process into the sampling process of document-topic distribution to overcome this limitation and maintain an easy optimization process. We validate our method through extensive experiments on two mainstream datasets, proving its effectiveness in improving topic modeling performance.

Prostate cancer is a leading cause of cancer-related deaths among men. The recent development of high frequency, micro-ultrasound imaging offers improved resolution compared to conventional ultrasound and potentially a better ability to differentiate clinically significant cancer from normal tissue. However, the features of prostate cancer remain subtle, with ambiguous borders with normal tissue and large variations in appearance, making it challenging for both machine learning and humans to localize it on micro-ultrasound images. We propose a novel Mask Enhanced Deeply-supervised Micro-US network, termed MedMusNet, to automatically and more accurately segment prostate cancer to be used as potential targets for biopsy procedures. MedMusNet leverages predicted masks of prostate cancer to enforce the learned features layer-wisely within the network, reducing the influence of noise and improving overall consistency across frames. MedMusNet successfully detected 76% of clinically significant cancer with a Dice Similarity Coefficient of 0.365, significantly outperforming the baseline Swin-M2F in specificity and accuracy (Wilcoxon test, Bonferroni correction, p-value<0.05). While the lesion-level and patient-level analyses showed improved performance compared to human experts and different baseline, the improvements did not reach statistical significance, likely on account of the small cohort. We have presented a novel approach to automatically detect and segment clinically significant prostate cancer on B-mode micro-ultrasound images. Our MedMusNet model outperformed other models, surpassing even human experts. These preliminary results suggest the potential for aiding urologists in prostate cancer diagnosis via biopsy and treatment decision-making.

The growing interest in autonomous driving calls for realistic simulation platforms capable of accurately simulating cooperative perception process in realistic traffic scenarios. Existing studies for cooperative perception often have not accounted for transmission latency and errors in real-world environments. To address this gap, we introduce EI-Drive, an edge-AI based autonomous driving simulation platform that integrates advanced cooperative perception with more realistic communication models. Built on the CARLA framework, EI-Drive features new modules for cooperative perception while taking into account transmission latency and errors, providing a more realistic platform for evaluating cooperative perception algorithms. In particular, the platform enables vehicles to fuse data from multiple sources, improving situational awareness and safety in complex environments. With its modular design, EI-Drive allows for detailed exploration of sensing, perception, planning, and control in various cooperative driving scenarios. Experiments using EI-Drive demonstrate significant improvements in vehicle safety and performance, particularly in scenarios with complex traffic flow and network conditions. All code and documents are accessible on our GitHub page: \url{https://ucd-dare.github.io/eidrive.github.io/}.

Sequential recommendation systems aim to provide personalized recommendations for users based on their interaction history. To achieve this, they often incorporate auxiliary information, such as textual descriptions of items and auxiliary tasks, like predicting user preferences and intent. Despite numerous efforts to enhance these models, they still suffer from limited personalization. To address this issue, we propose a new paradigm, which we term preference discerning. In preference dscerning, we explicitly condition a generative sequential recommendation system on user preferences within its context. To this end, we generate user preferences using Large Language Models (LLMs) based on user reviews and item-specific data. To evaluate preference discerning capabilities of sequential recommendation systems, we introduce a novel benchmark that provides a holistic evaluation across various scenarios, including preference steering and sentiment following. We assess current state-of-the-art methods using our benchmark and show that they struggle to accurately discern user preferences. Therefore, we propose a new method named Mender ($\textbf{M}$ultimodal Prefer$\textbf{en}$ce $\textbf{d}$iscern$\textbf{er}$), which improves upon existing methods and achieves state-of-the-art performance on our benchmark. Our results show that Mender can be effectively guided by human preferences even though they have not been observed during training, paving the way toward more personalized sequential recommendation systems. We will open-source the code and benchmarks upon publication.

We explore the feasibility and potential of building a ground-truth-free evaluation model to assess the quality of segmentations generated by the Segment Anything Model (SAM) and its variants in medical imaging. This evaluation model estimates segmentation quality scores by analyzing the coherence and consistency between the input images and their corresponding segmentation predictions. Based on prior research, we frame the task of training this model as a regression problem within a supervised learning framework, using Dice scores (and optionally other metrics) along with mean squared error to compute the training loss. The model is trained utilizing a large collection of public datasets of medical images with segmentation predictions from SAM and its variants. We name this model EvanySeg (Evaluation of Any Segmentation in Medical Images). Our exploration of convolution-based models (e.g., ResNet) and transformer-based models (e.g., ViT) suggested that ViT yields better performance for this task. EvanySeg can be employed for various tasks, including: (1) identifying poorly segmented samples by detecting low-percentile segmentation quality scores; (2) benchmarking segmentation models without ground truth by averaging quality scores across test samples; (3) alerting human experts to poor-quality segmentation predictions during human-AI collaboration by applying a threshold within the score space; and (4) selecting the best segmentation prediction for each test sample at test time when multiple segmentation models are available, by choosing the prediction with the highest quality score. Models and code will be made available at https://github.com/ahjolsenbics/EvanySeg.

Accuracy and timeliness are indeed often conflicting goals in prediction tasks. Premature predictions may yield a higher rate of false alarms, whereas delaying predictions to gather more information can render them too late to be useful. In applications such as wildfires, crimes, and traffic jams, timely forecasting are vital for safeguarding human life and property. Consequently, finding a balance between accuracy and timeliness is crucial. In this paper, we propose an early spatio-temporal forecasting model based on Multi-Objective reinforcement learning that can either implement an optimal policy given a preference or infer the preference based on a small number of samples. The model addresses two primary challenges: 1) enhancing the accuracy of early forecasting and 2) providing the optimal policy for determining the most suitable prediction time for each area. Our method demonstrates superior performance on three large-scale real-world datasets, surpassing existing methods in early spatio-temporal forecasting tasks.

The rapid development of spatial transcriptomics(ST) enables the measurement of gene expression at spatial resolution, making it possible to simultaneously profile the gene expression, spatial locations of spots, and the matched histopathological images. However, the cost for collecting ST data is much higher than acquiring histopathological images, and thus several studies attempt to predict the gene expression on ST by leveraging their corresponding histopathological images. Most of the existing image-based gene prediction models treat the prediction task on each spot of ST data independently, which ignores the spatial dependency among spots. In addition, while the histology images share phenotypic characteristics with the ST data, it is still challenge to extract such common information to help align paired image and expression representations. To address the above issues, we propose a Multi-view Graph Contrastive Learning framework with HSICbottleneck Regularization(ST-GCHB) aiming at learning shared representation to help impute the gene expression of the queried imaging spots by considering their spatial dependency. Specifically, ST-GCHB firstly adopts the intra-modal graph contrastive learning (GCL) to learn meaningful imaging and genomic features of spots by considering their spatial characteristics. Then, to reduce the redundancy for the extracted features of different modalities, we also add a HSIC-bottleneck regularization term in the GCL to enhance the efficiency of our model. Finally, an cross-modal contrastive learning strategy is applied to align the multi-modal data for imputing the spatially resolved gene expression data from the histopathological images.We conduct experiments on the dorsolateral prefrontal cortex (DLPFC) dataset and observe a significant improvement compared to the existing approaches. These results show the viability and effectiveness of our ST-GCHB for predicting molecular signatures of tissues from the histopathological images.

Spatiotemporal data is prevalent in a wide range of edge devices, such as those used in personal communication and financial transactions. Recent advancements have sparked a growing interest in integrating spatiotemporal analysis with large-scale language models. However, spatiotemporal data often contains sensitive information, making it unsuitable for open third-party access. To address this challenge, we propose a Graph-GAN-based model for generating privacy-protected spatiotemporal data. Our approach incorporates spatial and temporal attention blocks in the discriminator and a spatiotemporal deconvolution structure in the generator. These enhancements enable efficient training under Gaussian noise to achieve differential privacy. Extensive experiments conducted on three real-world spatiotemporal datasets validate the efficacy of our model. Our method provides a privacy guarantee while maintaining the data utility. The prediction model trained on our generated data maintains a competitive performance compared to the model trained on the original data.

Nowadays, large language models (LLMs) have been integrated with conventional recommendation models to improve recommendation performance. However, while most of the existing works have focused on improving the model performance, the privacy issue has only received comparatively less attention. In this paper, we review recent advancements in privacy within LLM-based recommendation, categorizing them into privacy attacks and protection mechanisms. Additionally, we highlight several challenges and propose future directions for the community to address these critical problems.