Lung cancer remains one of the leading causes of cancer-related mortality worldwide. A crucial challenge for early diagnosis is differentiating uncertain cases with similar visual characteristics and closely annotation scores. In clinical practice, radiologists rely on quantitative, hand-crafted Radiomic features extracted from Computed Tomography (CT) images, while recent research has primarily focused on deep learning solutions. More recently, Vision-Language Models (VLMs), particularly Contrastive Language-Image Pre-Training (CLIP)-based models, have gained attention for their ability to integrate textual knowledge into lung cancer diagnosis. While CLIP-Lung models have shown promising results, we identified the following potential limitations: (a) dependence on radiologists' annotated attributes, which are inherently subjective and error-prone, (b) use of textual information only during training, limiting direct applicability at inference, and (c) Convolutional-based vision encoder with randomly initialized weights, which disregards prior knowledge. To address these limitations, we introduce AutoRad-Lung, which couples an autoregressively pre-trained VLM, with prompts generated from hand-crafted Radiomics. AutoRad-Lung uses the vision encoder of the Large-Scale Autoregressive Image Model (AIMv2), pre-trained using a multi-modal autoregressive objective. Given that lung tumors are typically small, irregularly shaped, and visually similar to healthy tissue, AutoRad-Lung offers significant advantages over its CLIP-based counterparts by capturing pixel-level differences. Additionally, we introduce conditional context optimization, which dynamically generates context-specific prompts based on input Radiomics, improving cross-modal alignment.

Despite advancements in Computer-Aided Diagnosis (CAD) systems, breast cancer remains one of the leading causes of cancer-related deaths among women worldwide. Recent breakthroughs in Artificial Intelligence (AI) have shown significant promise in development of advanced Deep Learning (DL) architectures for breast cancer diagnosis through mammography. In this context, the paper focuses on the integration of AI within a Human-Centric workflow to enhance breast cancer diagnostics. Key challenges are, however, largely overlooked such as reliance on detailed tumor annotations and susceptibility to missing views, particularly during test time. To address these issues, we propose a hybrid, multi-scale and multi-view Swin Transformer-based framework (MSMV-Swin) that enhances diagnostic robustness and accuracy. The proposed MSMV-Swin framework is designed to work as a decision-support tool, helping radiologists analyze multi-view mammograms more effectively. More specifically, the MSMV-Swin framework leverages the Segment Anything Model (SAM) to isolate the breast lobe, reducing background noise and enabling comprehensive feature extraction. The multi-scale nature of the proposed MSMV-Swin framework accounts for tumor-specific regions as well as the spatial characteristics of tissues surrounding the tumor, capturing both localized and contextual information. The integration of contextual and localized data ensures that MSMV-Swin's outputs align with the way radiologists interpret mammograms, fostering better human-AI interaction and trust. A hybrid fusion structure is then designed to ensure robustness against missing views, a common occurrence in clinical practice when only a single mammogram view is available.

Driver emotion recognition plays a crucial role in driver monitoring systems, enhancing human-autonomy interactions and the trustworthiness of Autonomous Driving (AD). Various physiological and behavioural modalities have been explored for this purpose, with Electrocardiogram (ECG) emerging as a standout choice for real-time emotion monitoring, particularly in dynamic and unpredictable driving conditions. Existing methods, however, often rely on multi-channel ECG signals recorded under static conditions, limiting their applicability in real-world dynamic driving scenarios. To address this limitation, the paper introduces ECG-EmotionNet, a novel architecture designed specifically for emotion recognition in dynamic driving environments. ECG-EmotionNet is constructed by adapting a recently introduced ECG Foundation Model (FM) and uniquely employs single-channel ECG signals, ensuring both robust generalizability and computational efficiency. Unlike conventional adaptation methods such as full fine-tuning, linear probing, or low-rank adaptation, we propose an intuitively pleasing alternative, referred to as the nested Mixture of Experts (MoE) adaptation. More precisely, each transformer layer of the underlying FM is treated as a separate expert, with embeddings extracted from these experts fused using trainable weights within a gating mechanism. This approach enhances the representation of both global and local ECG features, leading to a 6% improvement in accuracy and a 7% increase in the F1 score, all while maintaining computational efficiency. The effectiveness of the proposed ECG-EmotionNet architecture is evaluated using a recently introduced and challenging driver emotion monitoring dataset.

MoEMba: A Mamba-based Mixture of Experts for High-Density EMG-based Hand Gesture Recognition Mehran Shabanpour, Kasra Rad, Sadaf Khademi, and Arash Mohammadi Abstract -- High-Density surface Electromyography (HD-sEMG) has emerged as a pivotal resource for Human-Computer Interaction (HCI), offering direct insights into muscle activities and motion intentions. However, a significant challenge in practical implementations of HD-sEMG-based models is the low accuracy of inter-session and inter-subject classification. V ariability between sessions can reach up to 40% due to the inherent temporal variability of HD-sEMG signals. T argeting this challenge, the paper introduces the MoEMba framework, a novel approach leveraging Selective State-Space Models (SSMs) to enhance HD-sEMG-based gesture recognition. Furthermore, wavelet feature modulation is integrated to capture multi-scale temporal and spatial relations, improving signal representation. Experimental results on the CapgMyo HD-sEMG dataset demonstrate that MoEMba achieves a balanced accuracy of 56 .9% The proposed framework's robustness to session-to-session variability and its efficient handling of high-dimensional multivariate time series data highlight its potential for advancing HD-sEMG-powered HCI systems.

--Mobile Edge Caching (MEC) plays a pivotal role in mitigating latency in data-intensive services by dynamically caching frequently requested content on edge servers. This capability is critical for applications such as Augmented Reality (AR), Virtual Reality (VR), and Autonomous V ehicles (A V), where efficient content caching and accurate popularity prediction are essential for optimizing performance. In this paper, we explore the problem of popularity prediction in MEC by utilizing historical time-series request data of intended files, formulating this problem as a ranking task. T o this aim, we propose CacheMamba model by employing Mamba, a state-space model (SSM)-based architecture, to identify the top-K files with the highest likelihood of being requested. We then benchmark the proposed model against a Transformer-based approach, demonstrating its superior performance in terms of cache-hit rate, Mean A ver-age Precision (MAP), Normalized Discounted Cumulative Gain (NDCG), and Floating-Point Operations Per Second (FLOPS), particularly when dealing with longer sequences.

Multi-channel surface Electromyography (sEMG), also referred to as high-density sEMG (HD-sEMG), plays a crucial role in improving gesture recognition performance for myoelectric control. Pattern recognition models developed based on HD-sEMG, however, are vulnerable to changing recording conditions (e.g., signal variability due to electrode shift). This has resulted in significant degradation in performance across subjects, and sessions. In this context, the paper proposes the Masked Autoencoder with Swin Transformer (MAST) framework, where training is performed on a masked subset of HDsEMG channels. A combination of four masking strategies, i.e., random block masking; temporal masking; sensor-wise random masking, and; multi-scale masking, is used to learn latent representations and increase robustness against electrode shift. The masked data is then passed through MAST's three-path encoder-decoder structure, leveraging a multi-path Swin-Unet architecture that simultaneously captures time-domain, frequency-domain, and magnitude-based features of the underlying HD-sEMG signal. These augmented inputs are then used in a self-supervised pre-training fashion to improve the model's generalization capabilities. Experimental results demonstrate the superior performance of the proposed MAST framework in comparison to its counterparts.

Recent statistics indicate that approximately 1.3 billion individuals worldwide suffer from hypertension, a leading cause of premature death globally. Blood pressure (BP) serves as a critical health indicator for accurate and timely diagnosis and/or treatment of hypertension. Driven by recent advancements in Artificial Intelligence (AI) and Deep Neural Networks (DNNs), there has been a surge of interest in developing data-driven and cuff-less BP estimation solutions. In this context, current literature predominantly focuses on coupling Electrocardiography (ECG) and Photoplethysmography (PPG) sensors, though this approach is constrained by reliance on multiple sensor types. An alternative, utilizing standalone PPG signals, presents challenges due to the absence of auxiliary sensors (ECG), requiring the use of morphological features while addressing motion artifacts and high-frequency noise. To address these issues, the paper introduces the TransfoRhythm framework, a Transformer-based DNN architecture built upon the recently released physiological database, MIMIC-IV. Leveraging Multi-Head Attention (MHA) mechanism, TransfoRhythm identifies dependencies and similarities across data segments, forming a robust framework for cuff-less BP estimation solely using PPG signals. To our knowledge, this paper represents the first study to apply the MIMIC IV dataset for cuff-less BP estimation, and TransfoRhythm is the first MHA-based model trained via MIMIC IV for BP prediction. Performance evaluation through comprehensive experiments demonstrates TransfoRhythm's superiority over its state-of-the-art counterparts. Specifically, TransfoRhythm achieves highly accurate results with Root Mean Square Error (RMSE) of [1.84, 1.42] and Mean Absolute Error (MAE) of [1.50, 1.17] for systolic and diastolic blood pressures, respectively.

Familial Hypercholesterolemia (FH) is a genetic disorder characterized by elevated levels of Low-Density Lipoprotein (LDL) cholesterol or its associated genes. Early-stage and accurate categorization of FH is of significance allowing for timely interventions to mitigate the risk of life-threatening conditions. Conventional diagnosis approach, however, is complex, costly, and a challenging interpretation task even for experienced clinicians resulting in high underdiagnosis rates. Although there has been a recent surge of interest in using Machine Learning (ML) models for early FH detection, existing solutions only consider a binary classification task solely using classical ML models. Despite its significance, application of Deep Learning (DL) for FH detection is in its infancy, possibly, due to categorical nature of the underlying clinical data. The paper addresses this gap by introducing the FH-TabNet, which is a multi-stage tabular DL network for multi-class (Definite, Probable, Possible, and Unlikely) FH detection. The FH-TabNet initially involves applying a deep tabular data learning architecture (TabNet) for primary categorization into healthy (Possible/Unlikely) and patient (Probable/Definite) classes. Subsequently, independent TabNet classifiers are applied to each subgroup, enabling refined classification. The model's performance is evaluated through 5-fold cross-validation illustrating superior performance in categorizing FH patients, particularly in the challenging low-prevalence subcategories.

Drawing inspiration from the primate brain's intriguing evidence accumulation process, and guided by models from cognitive psychology and neuroscience, the paper introduces the NYCTALE framework, a neuro-inspired and evidence accumulation-based Transformer architecture. The proposed neuro-inspired NYCTALE offers a novel pathway in the domain of Personalized Medicine (PM) for lung cancer diagnosis. In nature, Nyctales are small owls known for their nocturnal behavior, hunting primarily during the darkness of night. The NYCTALE operates in a similarly vigilant manner, i.e., processing data in an evidence-based fashion and making predictions dynamically/adaptively. Distinct from conventional Computed Tomography (CT)-based Deep Learning (DL) models, the NYCTALE performs predictions only when sufficient amount of evidence is accumulated. In other words, instead of processing all or a pre-defined subset of CT slices, for each person, slices are provided one at a time. The NYCTALE framework then computes an evidence vector associated with contribution of each new CT image. A decision is made once the total accumulated evidence surpasses a specific threshold. Preliminary experimental analyses conducted using a challenging in-house dataset comprising 114 subjects. The results are noteworthy, suggesting that NYCTALE outperforms the benchmark accuracy even with approximately 60% less training data on this demanding and small dataset.

Mobile Edge Caching (MEC) integrated with Deep Neural Networks (DNNs) is an innovative technology with significant potential for the future generation of wireless networks, resulting in a considerable reduction in users' latency. The MEC network's effectiveness, however, heavily relies on its capacity to predict and dynamically update the storage of caching nodes with the most popular contents. To be effective, a DNN-based popularity prediction model needs to have the ability to understand the historical request patterns of content, including their temporal and spatial correlations. Existing state-of-the-art time-series DNN models capture the latter by simultaneously inputting the sequential request patterns of multiple contents to the network, considerably increasing the size of the input sample. This motivates us to address this challenge by proposing a DNN-based popularity prediction framework based on the idea of contrasting input samples against each other, designed for the Unmanned Aerial Vehicle (UAV)-aided MEC networks. Referred to as the Contrastive Learning-based Survival Analysis (CLSA), the proposed architecture consists of a self-supervised Contrastive Learning (CL) model, where the temporal information of sequential requests is learned using a Long Short Term Memory (LSTM) network as the encoder of the CL architecture. Followed by a Survival Analysis (SA) network, the output of the proposed CLSA architecture is probabilities for each content's future popularity, which are then sorted in descending order to identify the Top-K popular contents. Based on the simulation results, the proposed CLSA architecture outperforms its counterparts across the classification accuracy and cache-hit ratio.