Retrieval approaches that score documents based on learned dense vectors (i.e., dense retrieval) rather than lexical signals (i.e., conventional retrieval) are increasingly popular. Their ability to identify related documents that do not necessarily contain the same terms as those appearing in the user's query (thereby improving recall) is one of their key advantages. However, to actually achieve these gains, dense retrieval approaches typically require an exhaustive search over the document collection, making them considerably more expensive at query-time than conventional lexical approaches. Several techniques aim to reduce this computational overhead by approximating the results of a full dense retriever. Although these approaches reasonably approximate the top results, they suffer in terms of recall -- one of the key advantages of dense retrieval. We introduce 'LADR' (Lexically-Accelerated Dense Retrieval), a simple-yet-effective approach that improves the efficiency of existing dense retrieval models without compromising on retrieval effectiveness. LADR uses lexical retrieval techniques to seed a dense retrieval exploration that uses a document proximity graph. We explore two variants of LADR: a proactive approach that expands the search space to the neighbors of all seed documents, and an adaptive approach that selectively searches the documents with the highest estimated relevance in an iterative fashion. Through extensive experiments across a variety of dense retrieval models, we find that LADR establishes a new dense retrieval effectiveness-efficiency Pareto frontier among approximate k nearest neighbor techniques. Further, we find that when tuned to take around 8ms per query in retrieval latency on our hardware, LADR consistently achieves both precision and recall that are on par with an exhaustive search on standard benchmarks.

We present an end-to-end, interpretable, deep-learning architecture to learn a graph kernel that predicts the outcome of chronic disease drug prescription. This is achieved through a deep metric learning collaborative with a Support Vector Machine objective using a graphical representation of Electronic Health Records. We formulate the predictive model as a binary graph classification problem with an adaptive learned graph kernel through novel cross-global attention node matching between patient graphs, simultaneously computing on multiple graphs without training pair or triplet generation. Results using the Taiwanese National Health Insurance Research Database demonstrate that our approach outperforms current start-of-the-art models both in terms of accuracy and interpretability.

The potential benefits of mining social media to learn about adverse drug reactions (ADRs) are rapidly increasing with the increasing popularity of social media. Unknown ADRs have traditionally been discovered by expensive post-marketing trials, but recent work has suggested that some unknown ADRs may be discovered by analyzing social media. We propose three methods for extracting ADRs from forum posts and tweets, and compare our methods with several existing methods. Our methods outperform the existing methods in several scenarios; our filtering method achieves the highest F1 and precision on forum posts, and our CRF method achieves the highest precision on tweets. Furthermore, we address the difficulty of annotating social media on a large scale with an alternate evaluation scheme that takes advantage of the ADRs listed on drug labels. We investigate how well this alternate evaluation approximates a traditional evaluation using human annotations.

Full natural language understanding requires identifying and analyzing the meanings of metaphors, which are ubiquitous in both text and speech. Over the last thirty years, linguistic metaphors have been shown to be based on more general conceptual metaphors, partial semantic mappings between disparate conceptual domains. Though some achievements have been made in identifying linguistic metaphors over the last decade or so, little work has been done to date on automatically identifying conceptual metaphors. This paper describes research on identifying conceptual metaphors based on corpus data. Our method uses as little background knowledge as possible, to ease transfer to new languages and to mini- mize any bias introduced by the knowledge base construction process. The method relies on general heuristics for identifying linguistic metaphors and statistical clustering (guided by Wordnet) to form conceptual metaphor candidates. Human experiments show the system effectively finds meaningful conceptual metaphors.