Semi-supervised Protein Classification Using Cluster Kernels

Weston, Jason, Zhou, Dengyong, Elisseeff, André, Noble, William S., Leslie, Christina S.

Neural Information Processing Systems 

A key issue in supervised protein classification is the representation of input sequencesof amino acids. Recent work using string kernels for protein datahas achieved state-of-the-art classification performance. However, suchrepresentations are based only on labeled data -- examples with known 3D structures, organized into structural classes -- while in practice, unlabeled data is far more plentiful.

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