Dynamic Stochastic Synapses as Computational Units

In most neural network models, synapses are treated as static weights that change only on the slow time scales of learning. In fact, however, synapses are highly dynamic, and show use-dependent plasticity over a wide range of time scales. Moreover, synaptic transmission is an inherently stochastic process: a spike arriving at a presynaptic terminal triggers release of a vesicle of neurotransmitter from a release site with a probability that can be much less than one. Changes in release probability represent one of the main mechanisms by which synaptic efficacy is modulated in neural circuits. We propose and investigate a simple model for dynamic stochastic synapses that can easily be integrated into common models for neural computation. We show through computer simulations and rigorous theoretical analysis that this model for a dynamic stochastic synapse increases computational power in a nontrivial way. Our results may have implications for the processing oftime-varying signals by both biological and artificial neural networks. A synapse 8 carries out computations on spike trains, more precisely on trains of spikes from the presynaptic neuron. Each spike from the presynaptic neuron mayor may not trigger the release of a neurotransmitter-filled vesicle at the synapse.