Population Decoding Based on an Unfaithful Model

We study a population decoding paradigm in which the maximum likelihood inferenceis based on an unfaithful decoding model (UMLI). This is usually the case for neural population decoding because the encoding process of the brain is not exactly known, or because a simplified decoding modelis preferred for saving computational cost. We consider an unfaithful decoding model which neglects the pairwise correlation between neuronal activities, and prove that UMLI is asymptotically efficient whenthe neuronal correlation is uniform or of limited-range. The performance of UMLI is compared with that of the maximum likelihood inference based on a faithful model and that of the center of mass decoding method.It turns out that UMLI has advantages of decreasing the computational complexity remarkablely and maintaining a high-level decoding accuracy at the same time. The effect of correlation on the decoding accuracy is also discussed.