Direction Selectivity In Primary Visual Cortex Using Massive Intracortical Connections

Almost all models of orientation and direction selectivity in visual cortex are based on feedforward connection schemes, where geniculate inputprovides all excitation to both pyramidal and inhibitory neurons. The latter neurons then suppress the response of the former fornon-optimal stimuli. However, anatomical studies show that up to 90 % of the excitatory synaptic input onto any cortical cellis provided by other cortical cells. The massive excitatory feedback nature of cortical circuits is embedded in the canonical microcircuit of Douglas &. Martin (1991). We here investigate analytically andthrough biologically realistic simulations the functioning of a detailed model of this circuitry, operating in a hysteretic mode. In the model, weak geniculate input is dramatically amplified byintracortical excitation, while inhibition has a dual role: (i) to prevent the early geniculate-induced excitation in the null direction and(ii) to restrain excitation and ensure that the neurons fire only when the stimulus is in their receptive-field.