Largest mammalian brain map ever could unpick what makes us human

The largest and most comprehensive 3D map of a mammalian brain to date offers an unprecedented insight into how neurons connect and function. The new map, which captures a cubic millimetre of a mouse's visual cortex, will allow scientists to study brain function in extraordinary detail, potentially revealing crucial insights into how neural activity shapes behaviour, how complex traits like consciousness arise, and even what it means to be human. "Our behaviours ultimately arise from activity in the brain, and brain tissue shares very similar properties in all mammals," says team member Forrest Collman at the Allen Institute for Brain Science in Seattle. "This is one reason we believe insights about the mouse cortex can generalise to humans." The achievement – something that biologist Francis Crick said in 1979 was "impossible" – took seven years to complete and involved 150 researchers from three institutions.