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'Alien-cortical' mice: Can human brain cells grow inside animals?

Al Jazeera

'Alien-cortical' mice: Can human brain cells grow inside animals? Share'Alien-cortical' mice: Can human brain cells grow inside animals? on social media In a laboratory in California, in the United States, mice are scurrying around their cages, as mice do. But inside their brains are millions of working human neurons. Researchers at Stanford University have implanted lab-grown human cells into mice genetically engineered to lack parts of their brains, including the cerebral cortex, the outer region that plays a major role in perception, movement, decision-making and attention. Putting human brain tissue inside an animal sounds like something out of Mary Shelley's Frankenstein, but how "human" are these mice, really?


Did the World Just Gain Hundreds of Millions of Alzheimer's Patients?

The New Yorker

Did the World Just Gain Hundreds of Millions of Alzheimer's Patients? A new definition of Alzheimer's includes people without symptoms. Experts are fiercely divided over whether that makes sense--and whether the new drugs really help. Many have heralded a golden age of Alzheimer's research, excited by the promise of new amyloid-targeting antibodies. Yet a large meta-study of such antibodies concluded that they probably result in "little to no difference" in the decline of memory and of cognitive ability. This July, some ten thousand people descended on London for the Alzheimer's Association International Conference. Another three thousand of us joined virtually. I'm an anthropologist, accustomed to conferences where croissants at coffee breaks count as a luxury. This one opened with six trumpeters dressed as Buckingham Palace guards, followed by dancers who discoed, vogued, and high-kicked through the history of British pop. After the first day's sessions, participants dispersed to parties; at one, singers in sequins belted out covers while someone played an illuminated, transparent violin. One night, the London Eye was lit purple to honor the people in attendance. The mood matched the spectacle. Joanne Pike, the Alzheimer's Association's president and C.E.O., announced that recent advances had brought the campaign against the disease to a "pivotal moment." Maria Carrillo, its chief science officer, hailed a groundswell of progress. That optimism followed decades of disappointment. Between 1974 and 2020, the U.S. government spent roughly twenty billion dollars on Alzheimer's research without seeing the approval of a single treatment designed to act on the disease's underlying biology, let alone stop or reverse its course. Today, Alzheimer's afflicts roughly one in nine Americans over sixty-five and, along with related dementias, has been estimated to cost the economy about three-quarters of a trillion dollars a year. In surveys, it ranks with cancer as the disease people fear most. It typically starts by robbing patients of recent memories--conversations they just had, where they put important objects--before corroding the basic functions of adult independence, from paying bills to managing medications. Eventually, it leaves patients unable to speak, move, swallow, or recognize close relatives.


How you can train your brain to enter an enchanted kingdom where you know you're dreaming - and can live out your wildest fantasies: DR BALAND JALAL

Daily Mail - Science & tech

You're viewing the US edition You can switch to the UK, AU or IE homepage at any time using this menu. Election guru Nate Silver makes his final midterm elections prediction... giving the GOP a glimmer of hope: Live updates Daily Mail finds child pornography in Thomas Markle's Mexico storage unit: Explicit images and pedophilia magazines uncovered as we report him to the FBI How Jordon Hudson, 25, quietly amassed multi-million real estate empire while hooking up with the sports legend, 74 before'ditching him for new man' Female teacher, 36, is jailed for just five years after she admitted giving birth to 13-year-old student's child After a week from hell, enter'Meghan of the Manor' (in a Kate lookalike wardrobe). So is this proof she really IS in Britain to stay? That's what friends are telling ALISON BOSHOFF... but she desperately needs the help of one VERY connected woman The British student who sparked outrage in France by mocking shopkeeper victims of Paris riots on TV chat show ...


The creepy science behind sleep paralysis 'demons'

Popular Science

Aliens, vampires, and ghosts have haunted our sleep for centuries. More information Adding us as a Preferred Source in Google by using this link indicates that you would like to see more of our content in Google News results. In 1781, Swiss artist Henry Fuseli painted this piece entitled The Nightmare. Sigmund Freud had a copy of the painting hung up in his Vienna apartment in the 1920s. Have you ever woken up in the dead of night to find your limbs locked tight?


Halloween Is a Chance to Rethink Your Relationship With Fear

TIME - Tech

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Are you really in the present moment? Your brain may be switching between two versions of reality 15 times a second, study claims

Daily Mail - Science & tech

You're viewing the US edition You can switch to the UK, AU or IE homepage at any time using this menu. Jaw-dropping new photos reveal most detailed look yet at Taylor Swift's wedding: Inside the reception... her scrapped carousel plans... and how they hid elaborate planning for months Trump labels Norway'a sh*thouse country' after he was overlooked for Nobel Peace Prize again America's military bases prepare for 90-day doomsday scenario Leaked Pentagon group chat reveals vulgar nickname for Trump-pick Army chief: Read texts laying bare ugly new war at very top of Pete Hegseth's department Tiny New York village home to just 2,600 people declared the'nicest place in America' RICHARD KAY: What insiders told me about whether Royals will reach out to Meghan and Harry. It's an opportunity to reconcile but there are risks - and the Palace is scrambling Bryan Kohberger's'passionate' prison calls amid shocking new bid for freedom... inside killer's state of mind and his chilling optimism to ...


Why Can't You Sit Still?

The New Yorker

We fight our nervous energy--but maybe we misunderstand what it's telling us. Long ago, when I was a fledgling journalist, I learned from an eminent editor about the concept of . It was a German word, he explained, that referred to the ability to sit still for a long time. "If you want to be a professional writer, you need," he told me. Although it was important to "get out there" and "report," it was also inevitable that I'd have to plant myself at a desk for whole days and weeks, focussing unremittingly on the production of words; many talented writers, he suggested, had failed to progress because they wrote beautifully but not for long enough.


Six wild ideas for perpetuating your mind

MIT Technology Review

The quest for cognitive immortality continues. Have you ever thought about what makes you? Science assures us it has everything to do with the three-pound organ between our ears, with its billions of neurons and trillions of delicate connections. But it's a lot trickier to explain why we have a sense of self-awareness or to pin down precisely where that first memory of Mommy actually resides. As we age, we forget most of what we've experienced, yet there's still undeniable continuity: At 30, or 50, or 70, you will still be you. To preserve that elusive continuity of self, some far-thinking technologists are working on ways to keep your brain going--even beyond death.


I use this free sleep tool to stop my mind from racing at night

PCWorld

The Dell Laptop Buying Guide UK: Which Dell Laptop Should You Buy? When you purchase through links in our articles, we may earn a small commission. Fall Asleep uses simple mental tricks such as breathing exercises, cognitive shuffling, and more to help quiet racing thoughts at bedtime. I don't know about you, but there've been countless times that I go to bed exhausted only for my brain to suddenly decide it's the perfect time to replay an awkward conversation from five years ago. If that sounds familiar, then I recommend giving the site Fall Asleep a try.


Nobel Prize awarded for showing how nerve cells shape feelings

BBC News

US psychiatrist and neurologist Karl Deisseroth and his German colleagues Peter Hegemann and Georg Nagel have been awarded this year's Nobel Prize in Physiology or Medicine for their work in the field of optogenetics. Their research has helped scientists learn more about the workings of the brain, to better understand how the human mind works. The Nobel Committee, external praised the trio for laying the foundation of a new era in neuroscience and revealing the neural circuits behind specific memories, feelings, and behaviours relevant for neurological and psychiatric disorders. In clinical medicine, researchers are using the method to try to restore sight in people with visual impairment . Optogenetics has fundamentally altered our understanding of the brain, the Nobel Assembly said.