5. Precision Medicine - Personalised Medicine and Life Sciences • SMASH


This thematic area relates to the'medicine of the future', principally the customisation of healthcare, with medical decisions, treatments, practises, or products being tailored to the individual patients, instead of a one‐drug‐ fits‐all model. Preventive or therapeutic interventions can then be targeted at those who will benefit, sparing expense and side effects for those who will not. Data analytics, including data mining and machine learning, is an integral part of the precision medicine model, e.g., in the discovery of new predictive or prognostic biomarkers or subgroups of patients. The number of papers reporting advances in this field are on almost an exponential rise since 2010 with Aaron Ciechanover, a Nobel Prize winner in Chemistry 2004, branding personalised medicine the "third revolution" of drug research. Neurodegenerative diseases, including Alzheimer's dementia (AD) and Parkinson's disease (PD), are caused by the progressive loss of structure or function of neurons.