Predicting Protein Functions using Machine Learning

The CAFA competitions use the Gene Ontology (GO) as the mechanism to annotate proteins. The ontology is a set of controlled vocabulary that is used to precisely define a term in question. The GO, in particular, defines terms for three different protein-related aspects (a.k.a. The GO is an "always evolving" set as new terms are incorporated, refined or made obsolete. The terms in the GO ontology are organized in a tree structure where each of them is given a unique identifier.