AI Lab of the Future Seeks to Build a Digital Cell

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The Technische Universität (TUU) KIWI biolab, which has been designated as one of three international artificial intelligence (AI) future laboratories by the German government, uses AI to design experiments with the aim of understanding how cells behave. "We cultivate various clones in parallel, and computer-controlled robots perform the fed-batch experiments and analyses automatically," explains Peter Neubauer, PhD, who heads the department of bioprocess engineering at TU Berlin. Experimental data is used to create "digital twins" of the cells that can be used for computer-based process development, he says. Neubauer developed the automated laboratory to multiply the number of cell lines he could analyze in parallel. "Currently in our facility we can do this for a large number of cells–for 48 different clones," he adds.