TileDB Launches Cross-Language Access to Single-Cell Data

TileDB, the database for any complex data and compute, announced the launch of TileDB-SOMA, the first collection of software libraries that implement the open-source SOMA API specification. SOMA and TileDB-SOMA are the result of a collaboration between the Chan Zuckerberg Initiative and TileDB to accelerate single-cell research by eliminating data silos and enable large-scale computations that are otherwise too challenging to execute on commodity hardware. "By streamlining access to enormous datasets, powerful new tools like TileDB-SOMA will accelerate the research efforts of single-cell biologists" New technologies and analysis tools have led to the exponential growth of single-cell RNA sequencing (scRNA-seq) data, requiring new solutions that can accommodate datasets at scale. Advancements in genomics technologies have also enabled researchers to combine multiple modalities of data collected from the same cell samples, increasing the complexity and impact of single-cell analysis. "The unsaid assumption in single-cell research is that dataset size is bound by RAM, but instead of asking researchers to change their computational tools, we're rethinking how the data model itself could do more heavy lifting for scientists," said Stavros Papadopoulos, Founder & CEO, TileDB, Inc. "With TileDB-SOMA for R and Python, computational biologists can work across programming languages and combine data that was previously formatted specifically for Seurat, Anndata/Scanpy or Bioconductor. This breaks down data silos, and allows scientists to collaborate without the hassle of converting or duplicating data. Everyone can access the dataset, stored locally or in the cloud, at any scale."