AlphaFold Teams up with Other AI Tools to Accelerate the Drug Discovery Process - CBIRT

Structure-based drug discovery (SBDD) is a standard method for identifying prospective medications for a target by leveraging its structural information. AlphaFold, a technique for predicting protein structure, has been regarded as a helpful resource for the discovery of therapeutics for new targets with low or no structural knowledge. In this study, the scientists utilized AlphaFold predictions as input for their AI-powered drug discovery engines (PandaOmics and Chemistry42) to efficiently identify a potential drug for CDK20 within 30 days. Understanding the structure of proteins is important in order to figure out their functions and the effect of change in amino acid sequence. The 3D structure of a protein allows us to visualize its functions and how genes and diseases are connected.