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Glowing algae could power the lamps of the future
The bioluminescent plants are a potential alternative to electrical light and batteries. More information Adding us as a Preferred Source in Google by using this link indicates that you would like to see more of our content in Google News results. Acidic (top) and basic (bottom) environments trigger different bioluminescent behaviors in algae. Breakthroughs, discoveries, and DIY tips sent six days a week. Bioluminescence is everywhere in nature, but it puts on its biggest light shows underwater .
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Discord Sleuths Gained Unauthorized Access to Anthropic's Mythos
Plus: Spy firms tap into a global telecom weakness to track targets, 500,000 UK health records go up for sale on Alibaba, Apple patches a revealing notification bug, and more. As researchers and practitioners debate the impact that new AI models will have on cybersecurity, Mozilla said on Tuesday it used early access to Anthropic's Mythos Preview to find and fix 271 vulnerabilities in its new Firefox 150 browser release. Meanwhile, researchers identified a group of moderately successful North Korean hackers using AI for everything from vibe coding malware to creating fake company websites--stealing up to $12 million in three months. Researchers have finally cracked disruptive malware known as Fast16 that predates Stuxnet and may have been used to target Iran's nuclear program. It was created in 2005 and was likely deployed by the US or an ally.
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Budget-Sensitive Discovery Scoring: A Formally Verified Framework for Evaluating AI-Guided Scientific Selection
Basu, Abhinaba, Chakraborty, Pavan
Scientific discovery increasingly relies on AI systems to select candidates for expensive experimental validation, yet no principled, budget-aware evaluation framework exists for comparing selection strategies -- a gap intensified by large language models (LLMs), which generate plausible scientific proposals without reliable downstream evaluation. We introduce the Budget-Sensitive Discovery Score (BSDS), a formally verified metric -- 20 theorems machine-checked by the Lean 4 proof assistant -- that jointly penalizes false discoveries (lambda-weighted FDR) and excessive abstention (gamma-weighted coverage gap) at each budget level. Its budget-averaged form, the Discovery Quality Score (DQS), provides a single summary statistic that no proposer can inflate by performing well at a cherry-picked budget. As a case study, we apply BSDS/DQS to: do LLMs add marginal value to an existing ML pipeline for drug discovery candidate selection? We evaluate 39 proposers -- 11 mechanistic variants, 14 zero-shot LLM configurations, and 14 few-shot LLM configurations -- using SMILES representations on MoleculeNet HIV (41,127 compounds, 3.5% active, 1,000 bootstrap replicates) under both random and scaffold splits. Three findings emerge. First, the simple RF-based Greedy-ML proposer achieves the best DQS (-0.046), outperforming all MLP variants and LLM configurations. Second, no LLM surpasses the Greedy-ML baseline under zero-shot or few-shot evaluation on HIV or Tox21, establishing that LLMs provide no marginal value over an existing trained classifier. Third, the proposer hierarchy generalizes across five MoleculeNet benchmarks spanning 0.18%-46.2% prevalence, a non-drug AV safety domain, and a 9x7 grid of penalty parameters (tau >= 0.636, mean tau = 0.863). The framework applies to any setting where candidates are selected under budget constraints and asymmetric error costs.
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Outrage over potentially cancer-curing drug hidden by CIA for years spirals as new patent surfaces
Kentucky mother and daughter turn down $26.5MILLION to sell their farms to secretive tech giant that wants to build data center there Horrifying next twist in the Alexander brothers case: MAUREEN CALLAHAN exposes an unthinkable perversion that's been hiding in plain sight Hollywood icon who starred in Psycho after Hitchcock dubbed her'my new Grace Kelly' looks incredible at 95 Kylie Jenner's total humiliation in Hollywood: Derogatory rumor leaves her boyfriend's peers'laughing at her' behind her back Tucker Carlson erupts at Trump adviser as she hurls'SLANDER' claim linking him to synagogue shooting Ben Affleck'scores $600m deal' with Netflix to sell his AI film start-up Long hair over 45 is ageing and try-hard. I've finally cut mine off. Alexander brothers' alleged HIGH SCHOOL rape video: Classmates speak out on sickening footage... as creepy unseen photos are exposed Heartbreaking video shows very elderly DoorDash driver shuffle down customer's driveway with coffee order because he is too poor to retire Amber Valletta, 52, was a '90s Vogue model who made movies with Sandra Bullock and Kate Hudson, see her now Model Cindy Crawford, 60, mocked for her'out of touch' morning routine: 'Nothing about this is normal' A US patent for a potential breakthrough cancer treatment is drawing renewed attention after declassified CIA documents revealed how scientists may have been close to a cure 60 years ago. The patent, published by Johns Hopkins University in 2021 and titled'Mebendazole Polymorph for Treatment and Prevention of Tumors,' outlines how specific formulations of the drug mebendazole may be used to target cancer cells. Mebendazole has been used safely for more than four decades to treat parasitic worm infections in humans, but researchers have increasingly investigated whether the drug could also help fight certain cancers, including aggressive brain tumors.
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CIA faces furious backlash after hidden document with potential cure for cancer is declassified after 60 years
Kentucky mother and daughter turn down $26.5MILLION to sell their farms to secretive tech giant that wants to build data center there Horrifying next twist in the Alexander brothers case: MAUREEN CALLAHAN exposes an unthinkable perversion that's been hiding in plain sight Hollywood icon who starred in Psycho after Hitchcock dubbed her'my new Grace Kelly' looks incredible at 95 Kylie Jenner's total humiliation in Hollywood: Derogatory rumor leaves her boyfriend's peers'laughing at her' behind her back Tucker Carlson erupts at Trump adviser as she hurls'SLANDER' claim linking him to synagogue shooting Ben Affleck'scores $600m deal' with Netflix to sell his AI film start-up Long hair over 45 is ageing and try-hard. I've finally cut mine off. Alexander brothers' alleged HIGH SCHOOL rape video: Classmates speak out on sickening footage... as creepy unseen photos are exposed Heartbreaking video shows very elderly DoorDash driver shuffle down customer's driveway with coffee order because he is too poor to retire Amber Valletta, 52, was a '90s Vogue model who made movies with Sandra Bullock and Kate Hudson, see her now Model Cindy Crawford, 60, mocked for her'out of touch' morning routine: 'Nothing about this is normal' A newly surfaced CIA document suggests US intelligence once reviewed research that hinted at a possible cancer treatment more than 60 years ago. The document, produced in February 1951 and declassified in 2014, summarizes a Soviet scientific paper that examined striking similarities between parasitic worms and cancerous tumors. The report describes how researchers believed both organisms thrived under nearly identical metabolic conditions and accumulated large reserves of glycogen, a form of stored energy.
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Supplement WelQrate: Defining the Gold Standard in Small Molecule Drug Discovery Benchmarking T able of Contents
If taking a closer look at the MedDRA classification on the system organ level on its website, we can find a claim of "System Organ Classes (SOCs) which are groupings by aetiology (e.g. However, as claimed in the original paper, "It should be noted that we did not perform any preprocessing of our datasets, such as Tab. These datasets appear in MoleculeNet as well. As mentioned in the introduction in the main paper, there are also issues with inconsistent representations and undefined stereochemistry. We list an example for each in Figure 1 and Figure 1.
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