A Computational Inflection for Scientific Discovery

Communications of the ACM 

We leverage research in natural language processing (NLP), information retrieval, data mining, and human-computer interaction (HCI) and draw concepts from multiple disciplines. For example, efforts in metascience focus on sociological factors that influence the evolution of science,17 such as analyses of information silos that impede mutual understanding and interaction,38 of macro-scale ramifications of the rapid growth in scholarly publications,4 and of current metrics for measuring impact5--work enabled by digitization of scholarly corpora. Metascience research makes important observations about human biases (desideratum 2) but generally does not engage in building computational interventions to augment researchers (desideratum 1). Conversely, work in literature-based discovery33 mines information from literature to generate new predictions (for example, functions of materials or drug targets) but is typically done in isolation from cognitive considerations; however, these techniques have great promise in being used as part of human-augmentation systems. Other work uses machines to automate aspects of science.