A Neural Network that Learns to Interpret Myocardial Planar Thallium Scintigrams

The planar thallium-201 myocardial perfusion scintigram is a widely used diagnostic technique for detecting and estimating the risk of coronary artery disease. Neural networks learned to interpret 100 thallium scintigrams as determined by individual expert ratings. Standard error backpropagation was compared to standard LMS, and LMS combined with one layer of RBF units. Using the "leave-one-out" method, generalization was tested on all 100 cases. Training time was determined automatically from cross-validation perfonnance. Best perfonnance was attained by the RBF/LMS network with three hidden units per view and compares favorably with human experts.