High-Resolution Boundary Detection for Medical Image Segmentation with Piece-Wise Two-Sample T-Test Augmented Loss

Fully automatic segmentation methods, such as liver and liver tumor segmentation, brain and brain tumor segmentation, optic disc segmentation, cell segmentation, lung segmentation, pulmonary nodule segmentation, and cardiac image segmentation [2], are essential for the diagnosis of serious diseases [3]. Therefore, it is important to improve the efficiency and accuracy of medical image segmentation methods. Medical image segmentation involves segmenting specific organs (e.g., the pancreas, liver, and bladder), determining certain functional parts of an organ (e.g., cardiac segmentation and retinal vessel segmentation), and identifying tumors in the organs. Medical images can generally be categorized according to the imaging technology and data form. Imaging technology includes X-ray photos, computed tomography, magnetic resonance imaging (MRI), and ultrasound imaging. Raw measurements are transformed into pixelated imaging data as part of the standard process. Although the original data are mostly three-dimensional images, two-dimensional slices are often created according to clinical procedure protocols that target specific applications. Most medical image segmentation methods are designed for two-dimensional slices.