Understanding the Artificial Intelligence Clinician and optimal treatment strategies for sepsis in intensive care
Komorowski, Matthieu, Celi, Leo A., Badawi, Omar, Gordon, Anthony C., Faisal, A. Aldo
–arXiv.org Artificial Intelligence
In this document, we explore in more detail our published work (Komorowski, Celi, Badawi, Gordon, & Faisal, 2018) for the benefit of the AI in Healthcare research community. In the above paper, we developed the AI Clinician system, which demonstrated how reinforcement learning could be used to make useful recommendations towards optimal treatment decisions from intensive care data. Since publication a number of authors have reviewed our work (e.g. Given the difference of our framework to previous work, the fact that we are bridging two very different academic communities (intensive care and machine learning) and that our work has impact on a number of other areas with more traditional computer-based approaches (biosignal processing and control, biomedical engineering), we are providing here additional details on our recent publication. We acknowledge the online comments by Jeter et al (https://arxiv.org/abs/1902.03271). The sections of the present document are structured so as to address some of their questions. For clarity, we label figures from our main Nature Medicine publication as "M", figures from Jeter et al.'s arXiv paper as "J" and figures from our response here as "R". Jeter et al. state "the only possible response we can afford is a more aggressive and open dialogue".
arXiv.org Artificial Intelligence
Mar-6-2019