Support Vector Regression for Right Censored Data

In many medical studies, estimating the failure time distribution function, or quantities that depend on this distribution, as a function of patient demographic and prognostic variables, is of central importance for risk assessment and health planing. Frequently, such data is subject to right censoring. The goal of this paper is to develop tools for analyzing such data using machine learning techniques. Traditional approaches to right censored failure time analysis include using parametric models, such as the Weibull distribution, and semiparametric models such as proportional hazard models (see Lawless, 2003, for both). Even when less stringent models--such as nonparametric estimation--are used, it is typically assumed that the distribution function is smooth in both time and covariates (Dabrowska, 1987; Gonzalez-Manteiga and Cadarso-Suarez, 1994). These assumptions seem restrictive, especially when considering today's high-dimensional data settings.