Managing Requirement Volatility in an Ontology-Driven Clinical LIMS Using Category Theory. International Journal of Telemedicine and Applications

Requirement volatility is an issue in software engineering in general, and in Web-based clinical applications in particular, which often originates from an incomplete knowledge of the domain of interest. With advances in the health science, many features and functionalities need to be added to, or removed from, existing software applications in the biomedical domain. At the same time, the increasing complexity of biomedical systems makes them more difficult to understand, and consequently it is more difficult to define their requirements, which contributes considerably to their volatility. In this paper, we present a novel agentbased approach for analyzing and managing volatile and dynamic requirements in an ontology-driven laboratory information management system (LIMS) designed for Web-based case reporting in medical mycology. The proposed framework is empowered with ontologies and formalized using category theory to provide a deep and common understanding of the 1 functional and nonfunctional requirement hierarchies and their interrelations, and to trace the effects of a change on the conceptual framework. Keywords: LIMS, requirement volatility, requirement change management, ontology, category theory, intelligent agents 1. Introduction The life sciences constitute a challenging domain in knowledge representation. Biological data are highly dynamic, and bioinformatics applications are large and there are complex interrelationships between their elements with various levels of interpretation for each concept. In an ideal situation, the requirements for a software system should be completely and unambiguously determined before design, coding, and testing take place. The complexity of bioinformatics applications and their constant evolution lead to frequent changes in their requirements: often new requirements are added and existing requirements are modified or deleted, causing parts of the software system to be redesigned, deleted, or added. Such changes lead to volatility in the requirements of bioinformatics applications. In this paper, we deal with an important problem of requirements volatility in the context of an ontology-driven clinical laboratory information management system (LIMS)[1, 2].