Ontologies
Automated Skill Decomposition Meets Expert Ontologies: Bridging the Granularity Gap with LLMs
Luyen, Le Ngoc, Abel, Marie-Hélène
This paper investigates automated skill decomposition using Large Language Models (LLMs) and proposes a rigorous, ontology-grounded evaluation framework. Our framework standardizes the pipeline from prompting and generation to normalization and alignment with ontology nodes. To evaluate outputs, we introduce two metrics: a semantic F1-score that uses optimal embedding-based matching to assess content accuracy, and a hierarchy-aware F1-score that credits structurally correct placements to assess granularity. We conduct experiments on ROME-ESCO-DecompSkill, a curated subset of parents, comparing two prompting strategies: zero-shot and leakage-safe few-shot with exemplars. Across diverse LLMs, zero-shot offers a strong baseline, while few-shot consistently stabilizes phrasing and granularity and improves hierarchy-aware alignment. A latency analysis further shows that exemplar-guided prompts are competitive - and sometimes faster - than unguided zero-shot due to more schema-compliant completions. Together, the framework, benchmark, and metrics provide a reproducible foundation for developing ontology-faithful skill decomposition systems.
FBS Model-based Maintenance Record Accumulation for Failure-Cause Inference in Manufacturing Systems
Fujiu, Takuma, Okazaki, Sho, Kaminishi, Kohei, Nakata, Yuji, Hamamoto, Shota, Yokose, Kenshin, Hara, Tatsunori, Umeda, Yasushi, Ota, Jun
In manufacturing systems, identifying the causes of failures is crucial for maintaining and improving production efficiency. In knowledge-based failure-cause inference, it is important that the knowledge base (1) explicitly structures knowledge about the target system and about failures, and (2) contains sufficiently long causal chains of failures. In this study, we constructed Diagnostic Knowledge Ontology and proposed a Function-Behavior-Structure (FBS) model-based maintenance-record accumulation method based on it. Failure-cause inference using the maintenance records accumulated by the proposed method showed better agreement with the set of candidate causes enumerated by experts, especially in difficult cases where the number of related cases is small and the vocabulary used differs. In the future, it will be necessary to develop inference methods tailored to these maintenance records, build a user interface, and carry out validation on larger and more diverse systems. Additionally, this approach leverages the understanding and knowledge of the target in the design phase to support knowledge accumulation and problem solving during the maintenance phase, and it is expected to become a foundation for knowledge sharing across the entire engineering chain in the future.
Steering Embedding Models with Geometric Rotation: Mapping Semantic Relationships Across Languages and Models
Freenor, Michael, Alvarez, Lauren
Understanding how language and embedding models encode semantic relationships is fundamental to model interpretability and control. While early word embeddings exhibited intuitive vector arithmetic (''king'' - ''man'' + ''woman'' = ''queen''), modern high-dimensional text representations lack straightforward interpretable geometric properties. We introduce Rotor-Invariant Shift Estimation (RISE), a geometric approach that represents semantic transformations as consistent rotational operations in embedding space, leveraging the manifold structure of modern language representations. RISE operations have the ability to operate across both languages and models with high transfer of performance, suggesting the existence of analogous cross-lingual geometric structure. We evaluate RISE across three embedding models, three datasets, and seven morphologically diverse languages in five major language groups. Our results demonstrate that RISE consistently maps discourse-level semantic transformations with distinct grammatical features (e.g., negation and conditionality) across languages and models. This work provides the first systematic demonstration that discourse-level semantic transformations correspond to consistent geometric operations in multilingual embedding spaces, empirically supporting the Linear Representation Hypothesis at the sentence level.
Real-Time Health Analytics Using Ontology-Driven Complex Event Processing and LLM Reasoning: A Tuberculosis Case Study
Chandra, Ritesh, Agarwal, Sonali, Singh, Navjot
Timely detection of critical health conditions remains a major challenge in public health analytics, especially in Big Data environments characterized by high volume, rapid velocity, and diverse variety of clinical data. This study presents an ontology-enabled real-time analytics framework that integrates Complex Event Processing (CEP) and Large Language Models (LLMs) to enable intelligent health event detection and semantic reasoning over heterogeneous, high-velocity health data streams. The architecture leverages the Basic Formal Ontology (BFO) and Semantic Web Rule Language (SWRL) to model diagnostic rules and domain knowledge. Patient data is ingested and processed using Apache Kafka and Spark Streaming, where CEP engines detect clinically significant event patterns. LLMs support adaptive reasoning, event interpretation, and ontology refinement. Clinical information is semantically structured as Resource Description Framework (RDF) triples in Graph DB, enabling SPARQL-based querying and knowledge-driven decision support. The framework is evaluated using a dataset of 1,000 Tuberculosis (TB) patients as a use case, demonstrating low-latency event detection, scalable reasoning, and high model performance (in terms of precision, recall, and F1-score). These results validate the system's potential for generalizable, real-time health analytics in complex Big Data scenarios.
GraphMERT: Efficient and Scalable Distillation of Reliable Knowledge Graphs from Unstructured Data
Belova, Margarita, Xiao, Jiaxin, Tuli, Shikhar, Jha, Niraj K.
Researchers have pursued neurosymbolic artificial intelligence (AI) applications for nearly three decades because symbolic components provide abstraction while neural components provide generalization. Thus, a marriage of the two components can lead to rapid advancements in AI. Yet, the field has not realized this promise since most neurosymbolic AI frameworks fail to scale. In addition, the implicit representations and approximate reasoning of neural approaches limit interpretability and trust. Knowledge graphs (KGs), a gold-standard representation of explicit semantic knowledge, can address the symbolic side. However, automatically deriving reliable KGs from text corpora has remained an open problem. We address these challenges by introducing GraphMERT, a tiny graphical encoder-only model that distills high-quality KGs from unstructured text corpora and its own internal representations. GraphMERT and its equivalent KG form a modular neurosymbolic stack: neural learning of abstractions; symbolic KGs for verifiable reasoning. GraphMERT + KG is the first efficient and scalable neurosymbolic model to achieve state-of-the-art benchmark accuracy along with superior symbolic representations relative to baselines. Concretely, we target reliable domain-specific KGs that are both (1) factual (with provenance) and (2) valid (ontology-consistent relations with domain-appropriate semantics). When a large language model (LLM), e.g., Qwen3-32B, generates domain-specific KGs, it falls short on reliability due to prompt sensitivity, shallow domain expertise, and hallucinated relations. On text obtained from PubMed papers on diabetes, our 80M-parameter GraphMERT yields a KG with a 69.8% FActScore; a 32B-parameter baseline LLM yields a KG that achieves only 40.2% FActScore. The GraphMERT KG also attains a higher ValidityScore of 68.8%, versus 43.0% for the LLM baseline.
A Model-Driven Engineering Approach to AI-Powered Healthcare Platforms
Raheem, Mira, Elgammal, Amal, Papazoglou, Michael, Krämer, Bernd, El-Tazi, Neamat
Artificial intelligence (AI) has the potential to transform healthcare by supporting more accurate diagnoses and personalized treatments. However, its adoption in practice remains constrained by fragmented data sources, strict privacy rules, and the technical complexity of building reliable clinical systems. To address these challenges, we introduce a model driven engineering (MDE) framework designed specifically for healthcare AI. The framework relies on formal metamodels, domain-specific languages (DSLs), and automated transformations to move from high level specifications to running software. At its core is the Medical Interoperability Language (MILA), a graphical DSL that enables clinicians and data scientists to define queries and machine learning pipelines using shared ontologies. When combined with a federated learning architecture, MILA allows institutions to collaborate without exchanging raw patient data, ensuring semantic consistency across sites while preserving privacy. We evaluate this approach in a multi center cancer immunotherapy study. The generated pipelines delivered strong predictive performance, with support vector machines achieving up to 98.5 percent and 98.3 percent accuracy in key tasks, while substantially reducing manual coding effort. These findings suggest that MDE principles metamodeling, semantic integration, and automated code generation can provide a practical path toward interoperable, reproducible, and trustworthy digital health platforms.
Agentic-KGR: Co-evolutionary Knowledge Graph Construction through Multi-Agent Reinforcement Learning
Li, Jing, Sun, Zhijie, Zhou, Zhicheng, Qiu, Suming, Huang, Junjie, Sun, Haijia, Qiu, Linyuan
Current knowledge-enhanced large language models (LLMs) rely on static, pre-constructed knowledge bases that suffer from coverage gaps and temporal obsolescence, limiting their effectiveness in dynamic information environments. We present Agentic-KGR, a novel framework enabling co-evolution between LLMs and knowledge graphs (KGs) through multi-round reinforcement learning (RL). Our approach introduces three key innovations: (1) a dynamic schema expansion mechanism that systematically extends graph ontologies beyond pre-defined boundaries during training; (2) a retrieval-augmented memory system enabling synergistic co-evolution between model parameters and knowledge structures through continuous optimization; (3) a learnable multi-scale prompt compression approach that preserves critical information while reducing computational complexity through adaptive sequence optimization. Experimental results demonstrate substantial improvements over supervised baselines and single-round RL approaches in knowledge extraction tasks. When integrated with GraphRAG, our method achieves superior performance in downstream QA tasks, with significant gains in both accuracy and knowledge coverage compared to existing methods.
Federated Data Analytics for Cancer Immunotherapy: A Privacy-Preserving Collaborative Platform for Patient Management
Raheem, Mira, Papazoglou, Michael, Krämer, Bernd, El-Tazi, Neamat, Elgammal, Amal
Connected health is a multidisciplinary approach focused on health management, prioritizing pa-tient needs in the creation of tools, services, and treatments. This paradigm ensures proactive and efficient care by facilitating the timely exchange of accurate patient information among all stake-holders in the care continuum. The rise of digital technologies and process innovations promises to enhance connected health by integrating various healthcare data sources. This integration aims to personalize care, predict health outcomes, and streamline patient management, though challeng-es remain, particularly in data architecture, application interoperability, and security. Data analytics can provide critical insights for informed decision-making and health co-creation, but solutions must prioritize end-users, including patients and healthcare professionals. This perspective was explored through an agile System Development Lifecycle in an EU-funded project aimed at developing an integrated AI-generated solution for managing cancer patients undergoing immunotherapy. This paper contributes with a collaborative digital framework integrating stakeholders across the care continuum, leveraging federated big data analytics and artificial intelligence for improved decision-making while ensuring privacy. Analytical capabilities, such as treatment recommendations and adverse event predictions, were validated using real-life data, achieving 70%-90% accuracy in a pilot study with the medical partners, demonstrating the framework's effectiveness.