Evidence-based recommendations are often published in the form of clinical guidelines and protocols, as documents intended to be used by clinicians to provide the state of the art care. However, as demonstrated repeatedly in multiple clinical domains, clinicians often do not sufficiently adhere to the guidelines in a manner sensitive to the context of each patient. Such gaps are important to detect; fast, large-scale detection might lead to specific adjustments, usually of the clinicians' management patterns, but possibly of the guidelines themselves. In this study, we evaluated the DiscovErr system, in which we had implemented a new methodology for assessment of compliance to continuous implementation of clinical guidelines. This new methodology is based on a bi-directional search from the objective of the guideline to the longitudinal multivariate patient data, and vice versa. The evaluation of DiscovErr was performed in the type 2 Diabetes management domain, by comparing its performance to a panel of three clinicians, two experts in diabetes-patient management and a senior family practitioner highly experienced in diabetes treatment. The system and the three experts commented on the management of 10 patients who were randomly selected before the evaluation from a database containing longitudinal records of 2,000 type 2 diabetes patients. On average, each patient record spanned 5.23 years; the overall data of the selected patients included 1,584 time-oriented medical transactions (laboratory tests or medication administrations). We assessed the correctness (i.e.

We propose a knowledge-based approach for extraction of Cause-Effect (CE) relations from biomedical text. Our approach is a combination of an unsupervised machine learning technique to discover causal triggers and a set of high-precision linguistic rules to identify cause/effect arguments of these causal triggers. We evaluate our approach using a corpus of 58,761 Leukaemia-related PubMed abstracts consisting of 568,528 sentences. We could extract 152,655 CE triplets from this corpus where each triplet consists of a cause phrase, an effect phrase and a causal trigger. As compared to the existing knowledge base - SemMedDB (Kilicoglu et al., 2012), the number of extractions are almost twice.

Many large-scale knowledge bases simultaneously represent two views of knowledge graphs (KGs): an ontology view for abstract and commonsense concepts, and an instance view for specific entities that are instantiated from ontological concepts. Existing KG embedding models, however, merely focus on representing one of the two views alone. In this paper, we propose a novel two-view KG embedding model, JOIE, with the goal to produce better knowledge embedding and enable new applications that rely on multi-view knowledge. JOIE employs both cross-view and intra-view modeling that learn on multiple facets of the knowledge base. The cross-view association model is learned to bridge the embeddings of ontological concepts and their corresponding instance-view entities. The intra-view models are trained to capture the structured knowledge of instance and ontology views in separate embedding spaces, with a hierarchy-aware encoding technique enabled for ontologies with hierarchies. We explore multiple representation techniques for the two model components and investigate with nine variants of JOIE. Our model is trained on large-scale knowledge bases that consist of massive instances and their corresponding ontological concepts connected via a (small) set of cross-view links. Experimental results on public datasets show that the best variant of JOIE significantly outperforms previous models on instance-view triple prediction task as well as ontology population on ontologyview KG. In addition, our model successfully extends the use of KG embeddings to entity typing with promising performance.

Individual investors are now massively using online brokers to trade stocks with convenient interfaces and low fees, albeit losing the advice and personalization traditionally provided by full-service brokers. We frame the problem faced by online brokers of replicating this level of service in a low-cost and automated manner for a very large number of users. Because of the care required in recommending financial products, we focus on a risk-management approach tailored to each user's portfolio and risk profile. We show that our hybrid approach, based on Modern Portfolio Theory and Collaborative Filtering, provides a sound and effective solution. The method is applicable to stocks as well as other financial assets, and can be easily combined with various financial forecasting models. We validate our proposal by comparing it with several baselines in a domain expert-based study.

Clinicians often do not sufficiently adhere to evidence-based clinical guidelines in a manner sensitive to the context of each patient. It is important to detect such deviations, typically including redundant or missing actions, even when the detection is performed retrospectively, so as to inform both the attending clinician and policy makers. Furthermore, it would be beneficial to detect such deviations in a manner proportional to the level of the deviation, and not to simply use arbitrary cut-off values. In this study, we introduce a new approach for automated guideline-based quality assessment of the care process, the bidirectional knowledge-based assessment of compliance (BiKBAC) method. Our BiKBAC methodology assesses the degree of compliance when applying clinical guidelines, with respect to multiple different aspects of the guideline (e.g., the guideline's process and outcome objectives). The assessment is performed through a highly detailed, automated quality-assessment retrospective analysis, which compares a formal representation of the guideline and of its process and outcome intentions (we use the Asbru language for that purpose) with the longitudinal electronic medical record of its continuous application over a significant time period, using both a top-down and a bottom-up approach, which we explain in detail. Partial matches of the data to the process and to the outcome objectives are resolved using fuzzy temporal logic. We also introduce the DiscovErr system, which implements the BiKBAC approach, and present its detailed architecture. The DiscovErr system was evaluated in a separate study in the type 2 diabetes management domain, by comparing its performance to a panel of three clinicians, with highly encouraging results with respect to the completeness and correctness of its comments.

In this paper we establish a link between preferential semantics for description logics and self-organising maps, which have been proposed as possible candidates to explain the psychological mechanisms underlying category generalisation. In particular, we show that a concept-wise multipreference semantics, which takes into account preferences with respect to different concepts and has been recently proposed for defeasible description logics, can be used to to provide a logical interpretation of SOMs. We also provide a logical interpretation of SOMs in terms of a fuzzy description logic as well as a probabilistic account.

Artificial intelligence systems, which are designed with a capability to learn from the data presented to them, are used throughout society. These systems are used to screen loan applicants, make sentencing recommendations for criminal defendants, scan social media posts for disallowed content and more. Because these systems don't assign meaning to their complex learned correlation network, they can learn associations that don't equate to causality, resulting in non-optimal and indefensible decisions being made. In addition to making decisions that are sub-optimal, these systems may create legal liability for their designers and operators by learning correlations that violate anti-discrimination and other laws regarding what factors can be used in different types of decision making. This paper presents the use of a machine learning expert system, which is developed with meaning-assigned nodes (facts) and correlations (rules). Multiple potential implementations are considered and evaluated under different conditions, including different network error and augmentation levels and different training levels. The performance of these systems is compared to random and fully connected networks.

Rule sets are often used in Machine Learning (ML) as a way to communicate the model logic in settings where transparency and intelligibility are necessary. Rule sets are typically presented as a text-based list of logical statements (rules). Surprisingly, to date there has been limited work on exploring visual alternatives for presenting rules. In this paper, we explore the idea of designing alternative representations of rules, focusing on a number of visual factors we believe have a positive impact on rule readability and understanding. The paper presents an initial design space for visualizing rule sets and a user study exploring their impact. The results show that some design factors have a strong impact on how efficiently readers can process the rules while having minimal impact on accuracy. This work can help practitioners employ more effective solutions when using rules as a communication strategy to understand ML models.

In my previous column, I looked at the problem of artificial intelligences forcing hardware to consume too much power, which could lead to an unsustainable spike in demand at data centers in this country by 2025. To test out their appetites for more power, I employed several advanced artificial intelligences, and also their close cousins machine learning, cognitive computing, deep learning and advanced expert system technology. For that column, I only measured how much power they consumed, but my original intention was to actually test them out to show some innovative things the technology was accomplishing. I am circling back to that effort now. For many years we have been reporting on the technology of artificial intelligence, about how it's being built out and made more efficient, or how it can be paired with other technologies like quantum computing to become even more accurate.

In this report, we investigate (element-based) inconsistency measures for multisets of business rule bases. Currently, related works allow to assess individual rule bases, however, as companies might encounter thousands of such instances daily, studying not only individual rule bases separately, but rather also their interrelations becomes necessary, especially in regard to determining suitable re-modelling strategies. We therefore present an approach to induce multiset-measures from arbitrary (traditional) inconsistency measures, propose new rationality postulates for a multiset use-case, and investigate the complexity of various aspects regarding multi-rule base inconsistency measurement.