In a multi-tenant large language model (LLM) serving platform hosting diverse applications, some users may submit an excessive number of requests, causing the service to become unavailable to other users and creating unfairness. Existing fairness approaches do not account for variations in token lengths across applications and multiple LLM calls, making them unsuitable for such platforms. To address the fairness challenge, this paper analyzes millions of requests from thousands of users on MS CoPilot, a real-world multi-tenant LLM platform hosted by Microsoft. Our analysis confirms the inadequacy of existing methods and guides the development of FairServe, a system that ensures fair LLM access across diverse applications. FairServe proposes application-characteristic aware request throttling coupled with a weighted service counter based scheduling technique to curb abusive behavior and ensure fairness. Our experimental results on real-world traces demonstrate FairServe's superior performance compared to the state-of-the-art method in ensuring fairness. We are actively working on deploying our system in production, expecting to benefit millions of customers world-wide.

Rapid development of artificial intelligence has drastically accelerated the development of scientific discovery. Trained with large-scale observation data, deep neural networks extract the underlying patterns in an end-to-end manner and assist human researchers with highly-precised predictions in unseen scenarios. The recent rise of Large Language Models (LLMs) and the empowered autonomous agents enable scientists to gain help through interaction in different stages of their research, including but not limited to literature review, research ideation, idea implementation, and academic writing. However, AI researchers instantiated by foundation model empowered agents with full-process autonomy are still in their infancy. In this paper, we study $\textbf{AI-Generated Science}$ (AIGS), where agents independently and autonomously complete the entire research process and discover scientific laws. By revisiting the definition of scientific research, we argue that $\textit{falsification}$ is the essence of both human research process and the design of an AIGS system. Through the lens of falsification, prior systems attempting towards AI-Generated Science either lack the part in their design, or rely heavily on existing verification engines that narrow the use in specialized domains. In this work, we propose Baby-AIGS as a baby-step demonstration of a full-process AIGS system, which is a multi-agent system with agents in roles representing key research process. By introducing FalsificationAgent, which identify and then verify possible scientific discoveries, we empower the system with explicit falsification. Experiments on three tasks preliminarily show that Baby-AIGS could produce meaningful scientific discoveries, though not on par with experienced human researchers. Finally, we discuss on the limitations of current Baby-AIGS, actionable insights, and related ethical issues in detail.

In-Context Operator Networks (ICONs) are models that learn operators across different types of PDEs using a few-shot, in-context approach. Although they show successful generalization to various PDEs, existing methods treat each data point as a single token, and suffer from computational inefficiency when processing dense data, limiting their application in higher spatial dimensions. In this work, we propose Vision In-Context Operator Networks (VICON), incorporating a vision transformer architecture that efficiently processes 2D functions through patch-wise operations. We evaluated our method on three fluid dynamics datasets, demonstrating both superior performance (reducing scaled $L^2$ error by $40\%$ and $61.6\%$ for two benchmark datasets for compressible flows, respectively) and computational efficiency (requiring only one-third of the inference time per frame) in long-term rollout predictions compared to the current state-of-the-art sequence-to-sequence model with fixed timestep prediction: Multiple Physics Pretraining (MPP). Compared to MPP, our method preserves the benefits of in-context operator learning, enabling flexible context formation when dealing with insufficient frame counts or varying timestep values.

Large Language Model (LLM) integrations into applications like Microsoft365 suite and Google Workspace for creating/processing documents, emails, presentations, etc. has led to considerable enhancements in productivity and time savings. But as these integrations become more more complex, it is paramount to ensure that the quality of output from the LLM-integrated applications are relevant and appropriate for use. Identifying the need to develop robust evaluation approaches for natural language generation, wherein references/ground labels doesn't exist or isn't amply available, this paper introduces a novel framework called "SAGEval" which utilizes a critiquing Agent to provide feedback on scores generated by LLM evaluators. We show that the critiquing Agent is able to rectify scores from LLM evaluators, in absence of references/ground-truth labels, thereby reducing the need for labeled data even for complex NLG evaluation scenarios, like the generation of JSON-structured forms/surveys with responses in different styles like multiple choice, likert ratings, single choice questions, etc.

Objectives: The vast and complex nature of human genomic sequencing data presents challenges for effective analysis. This review aims to investigate the application of Natural Language Processing (NLP) techniques, particularly Large Language Models (LLMs) and transformer architectures, in deciphering genomic codes, focusing on tokenization, transformer models, and regulatory annotation prediction. The goal of this review is to assess data and model accessibility in the most recent literature, gaining a better understanding of the existing capabilities and constraints of these tools in processing genomic sequencing data. Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, our scoping review was conducted across PubMed, Medline, Scopus, Web of Science, Embase, and ACM Digital Library. Studies were included if they focused on NLP methodologies applied to genomic sequencing data analysis, without restrictions on publication date or article type. Results: A total of 26 studies published between 2021 and April 2024 were selected for review. The review highlights that tokenization and transformer models enhance the processing and understanding of genomic data, with applications in predicting regulatory annotations like transcription-factor binding sites and chromatin accessibility. Discussion: The application of NLP and LLMs to genomic sequencing data interpretation is a promising field that can help streamline the processing of large-scale genomic data while also providing a better understanding of its complex structures. It has the potential to drive advancements in personalized medicine by offering more efficient and scalable solutions for genomic analysis. Further research is also needed to discuss and overcome current limitations, enhancing model transparency and applicability.

The International Workshop on Reading Music Systems (WoRMS) is a workshop that tries to connect researchers who develop systems for reading music, such as in the field of Optical Music Recognition, with other researchers and practitioners that could benefit from such systems, like librarians or musicologists. The relevant topics of interest for the workshop include, but are not limited to: Music reading systems; Optical music recognition; Datasets and performance evaluation; Image processing on music scores; Writer identification; Authoring, editing, storing and presentation systems for music scores; Multi-modal systems; Novel input-methods for music to produce written music; Web-based Music Information Retrieval services; Applications and projects; Use-cases related to written music. These are the proceedings of the 6th International Workshop on Reading Music Systems, held Online on November 22nd 2024.

This paper proposes a detailed prompting flow, termed Table-Logic, to investigate the performance contrasts between bigger and smaller language models (LMs) utilizing step-by-step reasoning methods in the TableQA task. The method processes tasks by sequentially identifying critical columns and rows given question and table with its structure, determining necessary aggregations, calculations, or comparisons, and finally inferring the results to generate a precise prediction. By deploying this method, we observe a 7.8% accuracy improvement in bigger LMs like Llama-3-70B compared to the vanilla on HybridQA, while smaller LMs like Llama-2-7B shows an 11% performance decline. We empirically investigate the potential causes of performance contrasts by exploring the capabilities of bigger and smaller LMs from various dimensions in TableQA task. Our findings highlight the limitations of the step-by-step reasoning method in small models and provide potential insights for making improvements.

Time series forecasting is critical in numerous real-world applications, requiring accurate predictions of future values based on observed patterns. While traditional forecasting techniques work well in in-domain scenarios with ample data, they struggle when data is scarce or not available at all, motivating the emergence of zero-shot and few-shot learning settings. Recent advancements often leverage large-scale foundation models for such tasks, but these methods require extensive data and compute resources, and their performance may be hindered by ineffective learning from the available training set. This raises a fundamental question: What factors influence effective learning from data in time series forecasting? Toward addressing this, we propose using Fourier analysis to investigate how models learn from synthetic and real-world time series data. Our findings reveal that forecasters commonly suffer from poor learning from data with multiple frequencies and poor generalization to unseen frequencies, which impedes their predictive performance. To alleviate these issues, we present a novel synthetic data generation framework, designed to enhance real data or replace it completely by creating task-specific frequency information, requiring only the sampling rate of the target data. Our approach, Freq-Synth, improves the robustness of both foundation as well as nonfoundation forecast models in zero-shot and few-shot settings, facilitating more reliable time series forecasting under limited data scenarios. Time series forecasting (TSF) plays a critical role in various areas, such as finance, healthcare, and energy, where accurate predictions of future values are essential for decision-making and planning. Traditionally, in-domain learning has been the common setting for developing forecasting models, where a model is trained using data from the same domain it will later be deployed in (Salinas et al., 2020; Zhou et al., 2021). This ensures that the model captures the patterns, seasonality, and trends specific to the target domain, improving its predictive performance. However, a significant challenge arises when there is scarce or no historical information available for training, limiting the ability to apply traditional in-domain learning approaches (Sarmas et al., 2022; Fong et al., 2020). In such cases, the emergence of zero-shot (ZS) and few-shot (FS) learning settings offer potential solutions. Zero-shot learning enables models to generalize to new, unseen domains without requiring domainspecific data by leveraging knowledge transfer from other domains or tasks.

Anomaly detection in clinical time-series holds significant potential in identifying suspicious patterns in different biological parameters. In this paper, we propose a targeted method that incorporates the clinical domain knowledge into LLMs to improve their ability to detect anomalies. We introduce the Metabolism Pathway-driven Prompting (MPP) method, which integrates the information about metabolic pathways to better capture the structural and temporal changes in biological samples. We applied our method for doping detection in sports, focusing on steroid metabolism, and evaluated using real-world data from athletes. The results show that our method improves anomaly detection performance by leveraging metabolic context, providing a more nuanced and accurate prediction of suspicious samples in athletes' profiles.

Agent-Based Modelling (ABM) has emerged as an essential tool for simulating social networks, encompassing diverse phenomena such as information dissemination, influence dynamics, and community formation. However, manually configuring varied agent interactions and information flow dynamics poses challenges, often resulting in oversimplified models that lack real-world generalizability. Integrating modern Large Language Models (LLMs) with ABM presents a promising avenue to address these challenges and enhance simulation fidelity, leveraging LLMs' human-like capabilities in sensing, reasoning, and behavior. In this paper, we propose a novel framework utilizing LLM-empowered agents to simulate social network users based on their interests and personality traits. The framework allows for customizable agent interactions resembling various social network platforms, including mechanisms for content resharing and personalized recommendations. We validate our framework using a comprehensive Twitter dataset from the 2020 US election, demonstrating that LLM-agents accurately replicate real users' behaviors, including linguistic patterns and political inclinations. These agents form homogeneous ideological clusters and retain the main themes of their community. Notably, preference-based recommendations significantly influence agent behavior, promoting increased engagement, network homophily and the formation of echo chambers. Overall, our findings underscore the potential of LLM-agents in advancing social media simulations and unraveling intricate online dynamics.