Accurate molecular quantification is essential for advancing research and diagnostics in fields such as infectious diseases, cancer biology, and genetic disorders. Droplet digital PCR (ddPCR) has emerged as a gold standard for achieving absolute quantification. While computational ddPCR technologies have advanced significantly, achieving automatic interpretation and consistent adaptability across diverse operational environments remains a challenge. To address these limitations, we introduce the intelligent interpretable droplet digital PCR (I2ddPCR) assay, a comprehensive framework integrating front-end predictive models (for droplet segmentation and classification) with GPT-4o multimodal large language model (MLLM, for context-aware explanations and recommendations) to automate and enhance ddPCR image analysis. This approach surpasses the state-of-the-art models, affording 99.05% accuracy in processing complex ddPCR images containing over 300 droplets per image with varying signal-to-noise ratios (SNRs). By combining specialized neural networks and large language models, the I2ddPCR assay offers a robust and adaptable solution for absolute molecular quantification, achieving a sensitivity capable of detecting low-abundance targets as low as 90.32 copies/{\mu}L. Furthermore, it improves model's transparency through detailed explanation and troubleshooting guidance, empowering users to make informed decisions. This innovative framework has the potential to benefit molecular diagnostics, disease research, and clinical applications, especially in resource-constrained settings.

Short text classification, as a research subtopic in natural language processing, is more challenging due to its semantic sparsity and insufficient labeled samples in practical scenarios. We propose a novel model named MI-DELIGHT for short text classification in this work. Specifically, it first performs multi-source information (i.e., statistical information, linguistic information, and factual information) exploration to alleviate the sparsity issues. Then, the graph learning approach is adopted to learn the representation of short texts, which are presented in graph forms. Moreover, we introduce a dual-level (i.e., instance-level and cluster-level) contrastive learning auxiliary task to effectively capture different-grained contrastive information within massive unlabeled data. Meanwhile, previous models merely perform the main task and auxiliary tasks in parallel, without considering the relationship among tasks. Therefore, we introduce a hierarchical architecture to explicitly model the correlations between tasks. We conduct extensive experiments across various benchmark datasets, demonstrating that MI-DELIGHT significantly surpasses previous competitive models. It even outperforms popular large language models on several datasets.

Visual-Spatial Systems has become increasingly essential in concrete crack inspection. However, existing methods often lacks adaptability to diverse scenarios, exhibits limited robustness in image-based approaches, and struggles with curved or complex geometries. To address these limitations, an innovative framework for two-dimensional (2D) crack detection, three-dimensional (3D) reconstruction, and 3D automatic crack measurement was proposed by integrating computer vision technologies and multi-modal Simultaneous localization and mapping (SLAM) in this study. Firstly, building on a base DeepLabv3+ segmentation model, and incorporating specific refinements utilizing foundation model Segment Anything Model (SAM), we developed a crack segmentation method with strong generalization across unfamiliar scenarios, enabling the generation of precise 2D crack masks. To enhance the accuracy and robustness of 3D reconstruction, Light Detection and Ranging (LiDAR) point clouds were utilized together with image data and segmentation masks. By leveraging both image- and LiDAR-SLAM, we developed a multi-frame and multi-modal fusion framework that produces dense, colorized point clouds, effectively capturing crack semantics at a 3D real-world scale. Furthermore, the crack geometric attributions were measured automatically and directly within 3D dense point cloud space, surpassing the limitations of conventional 2D image-based measurements. This advancement makes the method suitable for structural components with curved and complex 3D geometries. Experimental results across various concrete structures highlight the significant improvements and unique advantages of the proposed method, demonstrating its effectiveness, accuracy, and robustness in real-world applications.

Large Language Models (LLMs) have shown strong promise as rerankers, especially in ``listwise'' settings where an LLM is prompted to rerank several search results at once. However, this ``cascading'' retrieve-and-rerank approach is limited by the bounded recall problem: relevant documents not retrieved initially are permanently excluded from the final ranking. Adaptive retrieval techniques address this problem, but do not work with listwise rerankers because they assume a document's score is computed independently from other documents. In this paper, we propose an adaptation of an existing adaptive retrieval method that supports the listwise setting and helps guide the retrieval process itself (thereby overcoming the bounded recall problem for LLM rerankers). Specifically, our proposed algorithm merges results both from the initial ranking and feedback documents provided by the most relevant documents seen up to that point. Through extensive experiments across diverse LLM rerankers, first stage retrievers, and feedback sources, we demonstrate that our method can improve nDCG@10 by up to 13.23% and recall by 28.02%--all while keeping the total number of LLM inferences constant and overheads due to the adaptive process minimal. The work opens the door to leveraging LLM-based search in settings where the initial pool of results is limited, e.g., by legacy systems, or by the cost of deploying a semantic first-stage.

Many believe that use of generative AI as a private tutor has the potential to shrink access and achievement gaps between students and schools with abundant resources versus those with fewer resources. Shrinking the gap is possible only if paid and free versions of the platforms perform with the same accuracy. In this experiment, we investigate the performance of GPT versions 3.5, 4.0, and 4o-mini on the same 16-question statistics exam given to a class of first-year graduate students. While we do not advocate using any generative AI platform to complete an exam, the use of exam questions allows us to explore aspects of ChatGPT's responses to typical questions that students might encounter in a statistics course. Results on accuracy indicate that GPT 3.5 would fail the exam, GPT4 would perform well, and GPT4o-mini would perform somewhere in between. While we acknowledge the existence of other Generative AI/LLMs, our discussion concerns only ChatGPT because it is the most widely used platform on college campuses at this time. We further investigate differences among the AI platforms in the answers for each problem using methods developed for text analytics, such as reading level evaluation and topic modeling. Results indicate that GPT3.5 and 4o-mini have characteristics that are more similar than either of them have with GPT4.

Vision Language Models (VLMs) demonstrate significant potential as embodied AI agents for various mobility applications. However, a standardized, closed-loop benchmark for evaluating their spatial reasoning and sequential decision-making capabilities is lacking. To address this, we present MetaVQA: a comprehensive benchmark designed to assess and enhance VLMs' understanding of spatial relationships and scene dynamics through Visual Question Answering (VQA) and closed-loop simulations. MetaVQA leverages Set-of-Mark prompting and top-down view ground-truth annotations from nuScenes and Waymo datasets to automatically generate extensive question-answer pairs based on diverse real-world traffic scenarios, ensuring object-centric and context-rich instructions. Our experiments show that fine-tuning VLMs with the MetaVQA dataset significantly improves their spatial reasoning and embodied scene comprehension in safety-critical simulations, evident not only in improved VQA accuracies but also in emerging safety-aware driving maneuvers. In addition, the learning demonstrates strong transferability from simulation to real-world observation. Code and data will be publicly available at https://metadriverse.github.io/metavqa .

This work introduces a novel Retention Layer mechanism for Transformer based architectures, addressing their inherent lack of intrinsic retention capabilities. Unlike human cognition, which can encode and dynamically recall symbolic templates, Generative Pretrained Transformers rely solely on fixed pretrained weights and ephemeral context windows, limiting their adaptability. The proposed Retention Layer incorporates a persistent memory module capable of real time data population, dynamic recall, and guided output generation. This enhancement allows models to store, update, and reuse observed patterns across sessions, enabling incremental learning and bridging the gap between static pretraining and dynamic, context sensitive adaptation. The Retention Layer design parallels social learning processes, encompassing attention, retention, reproduction, and motivation stages. Technically, it integrates a memory attention mechanism and episodic buffers to manage memory scalability, mitigate overfitting, and ensure efficient recall. Applications span adaptive personal assistants, real time fraud detection, autonomous robotics, content moderation, and healthcare diagnostics. In each domain, the retention mechanism enables systems to learn incrementally, personalize outputs, and respond to evolving real world challenges effectively. By emulating key aspects of human learning, this retention enhanced architecture fosters a more fluid and responsive AI paradigm, paving the way for dynamic, session aware models that extend the capabilities of traditional Transformers into domains requiring continual adaptation.

In this work, we address the challenge of evaluating large language models (LLMs) on the short answer matching task for Latvian and Lithuanian languages. We introduce novel datasets consisting of 502 Latvian and 690 Lithuanian question-answer pairs. For each question-answer pair, we generated matched and non-matched answers using a set of alteration rules specifically designed to introduce small but meaningful changes in the text. These generated answers serve as test cases to assess the ability of LLMs to detect subtle differences in matching of the original answers. A subset of the datasets was manually verified for quality and accuracy. Our results show that while larger LLMs, such as QWEN2.5 72b and LLaMa3.1 70b, demonstrate near-perfect performance in distinguishing matched and non-matched answers, smaller models show more variance. For instance, LLaMa3.1 8b and EuroLLM 9b benefited from few-shot examples, while Mistral Nemo 12b underperformed on detection of subtle text alteration, particularly in Lithuanian, even with additional examples. QWEN2.5 7b and Mistral 7b were able to obtain a strong and comparable performance to the larger 70b models in zero and few shot experiments. Moreover, the performance of Mistral 7b was weaker in few shot experiments.

In this work, we evaluated Lithuanian and general history knowledge of multilingual Large Language Models (LLMs) on a multiple-choice question-answering task. The models were tested on a dataset of Lithuanian national and general history questions translated into Baltic, Nordic, and other languages (English, Ukrainian, Arabic) to assess the knowledge sharing from culturally and historically connected groups. We evaluated GPT-4o, LLaMa3.1 8b and 70b, QWEN2.5 7b and 72b, Mistral Nemo 12b, LLaMa3 8b, Mistral 7b, LLaMa3.2 3b, and Nordic fine-tuned models (GPT-SW3 and LLaMa3 8b). Our results show that GPT-4o consistently outperformed all other models across language groups, with slightly better results for Baltic and Nordic languages. Larger open-source models like QWEN2.5 72b and LLaMa3.1 70b performed well but showed weaker alignment with Baltic languages. Smaller models (Mistral Nemo 12b, LLaMa3.2 3b, QWEN 7B, LLaMa3.1 8B, and LLaMa3 8b) demonstrated gaps with LT-related alignment with Baltic languages while performing better on Nordic and other languages. The Nordic fine-tuned models did not surpass multilingual models, indicating that shared cultural or historical context alone does not guarantee better performance.

Bilingual lexical processing is shaped by the complex interplay of phonological, orthographic, and semantic features of two languages within an integrated mental lexicon. In humans, this is evident in the ease with which cognate words - words similar in both orthographic form and meaning (e.g., blind, meaning "sightless" in both English and German) - are processed, compared to the challenges posed by interlingual homographs, which share orthographic form but differ in meaning (e.g., gift, meaning "present" in English but "poison" in German). We investigate how multilingual Large Language Models (LLMs) handle such phenomena, focusing on English-Spanish, English-French, and English-German cognates, non-cognate, and interlingual homographs. Specifically, we evaluate their ability to disambiguate meanings and make semantic judgments, both when these word types are presented in isolation or within sentence contexts. Our findings reveal that while certain LLMs demonstrate strong performance in recognizing cognates and non-cognates in isolation, they exhibit significant difficulty in disambiguating interlingual homographs, often performing below random baselines. This suggests LLMs tend to rely heavily on orthographic similarities rather than semantic understanding when interpreting interlingual homographs. Further, we find LLMs exhibit difficulty in retrieving word meanings, with performance in isolative disambiguation tasks having no correlation with semantic understanding. Finally, we study how the LLM processes interlingual homographs in incongruent sentences. We find models to opt for different strategies in understanding English and non-English homographs, highlighting a lack of a unified approach to handling cross-lingual ambiguities.