Trustworthy prediction in Deep Neural Networks (DNNs), including Pre-trained Language Models (PLMs) is important for safety-critical applications in the real world. However, DNNs often suffer from uncertainty estimation, such as miscalibration. In particular, approaches that require multiple stochastic inference can mitigate this problem, but the expensive cost of inference makes them impractical. In this study, we propose $k$-Nearest Neighbor Uncertainty Estimation ($k$NN-UE), which is an uncertainty estimation method that uses the distances from the neighbors and label-existence ratio of neighbors. Experiments on sentiment analysis, natural language inference, and named entity recognition show that our proposed method outperforms the baselines or recent density-based methods in confidence calibration, selective prediction, and out-of-distribution detection. Moreover, our analyses indicate that introducing dimension reduction or approximate nearest neighbor search inspired by recent $k$NN-LM studies reduces the inference overhead without significantly degrading estimation performance when combined them appropriately.

Retrieval-augmented text generation (RAG) addresses the common limitations of large language models (LLMs), such as hallucination, by retrieving information from an updatable external knowledge base. However, existing approaches often require dedicated backend servers for data storage and retrieval, thereby limiting their applicability in use cases that require strict data privacy, such as personal finance, education, and medicine. To address the pressing need for client-side dense retrieval, we introduce MeMemo, the first open-source JavaScript toolkit that adapts the state-of-the-art approximate nearest neighbor search technique HNSW to browser environments. Developed with modern and native Web technologies, such as IndexedDB and Web Workers, our toolkit leverages client-side hardware capabilities to enable researchers and developers to efficiently search through millions of high-dimensional vectors in the browser. MeMemo enables exciting new design and research opportunities, such as private and personalized content creation and interactive prototyping, as demonstrated in our example application RAG Playground. Reflecting on our work, we discuss the opportunities and challenges for on-device dense retrieval. MeMemo is available at https://github.com/poloclub/mememo.

Conversational Query Reformulation (CQR) has significantly advanced in addressing the challenges of conversational search, particularly those stemming from the latent user intent and the need for historical context. Recent works aimed to boost the performance of CRQ through alignment. However, they are designed for one specific retrieval system, which potentially results in poor generalization. To overcome this limitation, we present a novel framework AdaCQR. By aligning reformulation models with both term-based and semantic-based retrieval systems, AdaCQR enhances the generalizability of information-seeking queries across diverse retrieval environments through a dual-phase training strategy. We also developed two effective approaches for acquiring superior labels and diverse input candidates, boosting the efficiency and robustness of the framework. Experimental evaluations on the TopiOCQA and QReCC datasets demonstrate that AdaCQR significantly outperforms existing methods, offering both quantitative and qualitative improvements in conversational query reformulation.

We use the encoder-decoder T5 model only a small number of parameters is updated to (Raffel et al., 2020) for all experiments to take a downstream task (Houlsby et al., 2019; Stickland advantage of modelling the tasks as sequence-tosequence and Murray, 2019; Karimi Mahabadi et al., tasks. We test our model in seven datasets 2021a). These methods aim to achieve comparable from two Sequence Labelling tasks. The first task performance to full fine-tuning by updating as few is Named Entity Recognition, a valuable tool in parameters as possible. However, a less studied research various real-world scenarios in the era of large language direction related to these methods is whether models such as healthcare and medical research one can perform better than full fine-tuning with (Raza et al., 2022; Hu et al., 2024), Finance fewer parameters (Mao et al., 2022).

The proliferation of Large Language Models (LLMs) has led to an influx of AI-generated content (AIGC) on the internet, transforming the corpus of Information Retrieval (IR) systems from solely human-written to a coexistence with LLM-generated content. The impact of this surge in AIGC on IR systems remains an open question, with the primary challenge being the lack of a dedicated benchmark for researchers. In this paper, we introduce Cocktail, a comprehensive benchmark tailored for evaluating IR models in this mixed-sourced data landscape of the LLM era. Cocktail consists of 16 diverse datasets with mixed human-written and LLM-generated corpora across various text retrieval tasks and domains. Additionally, to avoid the potential bias from previously included dataset information in LLMs, we also introduce an up-to-date dataset, named NQ-UTD, with queries derived from recent events. Through conducting over 1,000 experiments to assess state-of-the-art retrieval models against the benchmarked datasets in Cocktail, we uncover a clear trade-off between ranking performance and source bias in neural retrieval models, highlighting the necessity for a balanced approach in designing future IR systems. We hope Cocktail can serve as a foundational resource for IR research in the LLM era, with all data and code publicly available at \url{https://github.com/KID-22/Cocktail}.

The traditional evaluation of information retrieval (IR) systems is generally very costly as it requires manual relevance annotation from human experts. Recent advancements in generative artificial intelligence -- specifically large language models (LLMs) -- can generate relevance annotations at an enormous scale with relatively small computational costs. Potentially, this could alleviate the costs traditionally associated with IR evaluation and make it applicable to numerous low-resource applications. However, generated relevance annotations are not immune to (systematic) errors, and as a result, directly using them for evaluation produces unreliable results. In this work, we propose two methods based on prediction-powered inference and conformal risk control that utilize computer-generated relevance annotations to place reliable confidence intervals (CIs) around IR evaluation metrics. Our proposed methods require a small number of reliable annotations from which the methods can statistically analyze the errors in the generated annotations. Using this information, we can place CIs around evaluation metrics with strong theoretical guarantees. Unlike existing approaches, our conformal risk control method is specifically designed for ranking metrics and can vary its CIs per query and document. Our experimental results show that our CIs accurately capture both the variance and bias in evaluation based on LLM annotations, better than the typical empirical bootstrapping estimates. We hope our contributions bring reliable evaluation to the many IR applications where this was traditionally infeasible.

Identifying patient cohorts is fundamental to numerous healthcare tasks, including clinical trial recruitment and retrospective studies. Current cohort retrieval methods in healthcare organizations rely on automated queries of structured data combined with manual curation, which are time-consuming, labor-intensive, and often yield low-quality results. Recent advancements in large language models (LLMs) and information retrieval (IR) offer promising avenues to revolutionize these systems. Major challenges include managing extensive eligibility criteria and handling the longitudinal nature of unstructured Electronic Medical Records (EMRs) while ensuring that the solution remains cost-effective for real-world application. This paper introduces a new task, Automatic Cohort Retrieval (ACR), and evaluates the performance of LLMs and commercial, domain-specific neuro-symbolic approaches. We provide a benchmark task, a query dataset, an EMR dataset, and an evaluation framework. Our findings underscore the necessity for efficient, high-quality ACR systems capable of longitudinal reasoning across extensive patient databases.

Conversational search systems enable information retrieval via natural language interactions, with the goal of maximizing users' information gain over multiple dialogue turns. The increasing prevalence of conversational interfaces adopting this search paradigm challenges traditional information retrieval approaches, stressing the importance of better understanding the engineering process of developing these systems. We undertook a systematic literature review to investigate the links between theoretical studies and technical implementations of conversational search systems. Our review identifies real-world application scenarios, system architectures, and functional components. We consolidate our results by presenting a layered architecture framework and explaining the core functions of conversational search systems. Furthermore, we reflect on our findings in light of the rapid progress in large language models, discussing their capabilities, limitations, and directions for future research.

A dense passage retrieval system can serve as the initial stages of information retrieval, selecting the most relevant text passages for downstream tasks. In this work we conducted experiments with the goal of finding how much the quality of a multilingual retrieval could be degraded if the query part of a dual encoder is tuned on an English-only dataset (assuming scarcity of cross-lingual samples for the targeted domain or task). Specifically, starting with a high quality multilingual embedding model, we observe that an English-only tuning may not only preserve the original quality of the multilingual retrieval, but even improve it.

Recent successes in virtual screening have been made possible by large models and extensive chemical libraries. However, combining these elements is challenging: the larger the model, the more expensive it is to run, making ultra-large libraries unfeasible. To address this, we developed a target-agnostic, efficacy-based molecule search model, which allows us to find structurally dissimilar molecules with similar biological activities. We used the best practices to design fast retrieval system, based on processor-optimized SIMD instructions, enabling us to screen the ultra-large 40B Enamine REAL library with 100\% recall rate. We extensively benchmarked our model and several state-of-the-art models for both speed performance and retrieval quality of novel molecules.