Optimal allocation of scarce resources is a common problem for decision makers faced with choosing a limited number of locations for intervention. Spatiotemporal prediction models could make such decisions data-driven. A recent performance metric called fraction of best possible reach (BPR) measures the impact of using a model's recommended size K subset of sites compared to the best possible top-K in hindsight. We tackle two open problems related to BPR. First, we explore how to rank all sites numerically given a probabilistic model that predicts event counts jointly across sites. Ranking via the per-site mean is suboptimal for BPR. Instead, we offer a better ranking for BPR backed by decision theory. Second, we explore how to train a probabilistic model's parameters to maximize BPR. Discrete selection of K sites implies all-zero parameter gradients which prevent standard gradient training. We overcome this barrier via advances in perturbed optimizers. We further suggest a training objective that combines likelihood with a decision-aware BPR constraint to deliver high-quality top-K rankings as well as good forecasts for all sites. We demonstrate our approach on two where-to-intervene applications: mitigating opioid-related fatal overdoses for public health and monitoring endangered wildlife.

Artificial intelligence (AI) has achieved astonishing successes in many domains, especially with the recent breakthroughs in the development of foundational large models. These large models, leveraging their extensive training data, provide versatile solutions for a wide range of downstream tasks. However, as modern datasets become increasingly diverse and complex, the development of large AI models faces two major challenges: (1) the enormous consumption of computational resources and deployment difficulties, and (2) the difficulty in fitting heterogeneous and complex data, which limits the usability of the models. Mixture of Experts (MoE) models has recently attracted much attention in addressing these challenges, by dynamically selecting and activating the most relevant sub-models to process input data. It has been shown that MoEs can significantly improve model performance and efficiency with fewer resources, particularly excelling in handling large-scale, multimodal data. Given the tremendous potential MoE has demonstrated across various domains, it is urgent to provide a comprehensive summary of recent advancements of MoEs in many important fields. Existing surveys on MoE have their limitations, e.g., being outdated or lacking discussion on certain key areas, and we aim to address these gaps. In this paper, we first introduce the basic design of MoE, including gating functions, expert networks, routing mechanisms, training strategies, and system design. We then explore the algorithm design of MoE in important machine learning paradigms such as continual learning, meta-learning, multi-task learning, and reinforcement learning. Additionally, we summarize theoretical studies aimed at understanding MoE and review its applications in computer vision and natural language processing. Finally, we discuss promising future research directions.

Wearable health devices have a strong demand in real-time biomedical signal processing. However traditional methods often require data transmission to centralized processing unit with substantial computational resources after collecting it from edge devices. Neuromorphic computing is an emerging field that seeks to design specialized hardware for computing systems inspired by the structure, function, and dynamics of the human brain, offering significant advantages in latency and power consumption. This paper explores a novel neuromorphic implementation approach for gesture recognition by extracting spatiotemporal spiking information from surface electromyography (sEMG) data in an event-driven manner. At the same time, the network was designed by implementing a simple-structured and hardware-friendly Physical Reservoir Computing (PRC) framework called Rotating Neuron Reservoir (RNR) within the domain of Spiking neural network (SNN). The spiking RNR (sRNR) is promising to pipeline an innovative solution to compact embedded wearable systems, enabling low-latency, real-time processing directly at the sensor level. The proposed system was validated by an open-access large-scale sEMG database and achieved an average classification accuracy of 74.6\% and 80.3\% using a classical machine learning classifier and a delta learning rule algorithm respectively. While the delta learning rule could be fully spiking and implementable on neuromorphic chips, the proposed gesture recognition system demonstrates the potential for near-sensor low-latency processing.

Patient mobility monitoring in intensive care is critical for ensuring timely interventions and improving clinical outcomes. While accelerometry-based sensor data are widely adopted in training artificial intelligence models to estimate patient mobility, existing approaches face two key limitations highlighted in clinical practice: (1) modeling the long-term accelerometer data is challenging due to the high dimensionality, variability, and noise, and (2) the absence of efficient and robust methods for long-term mobility assessment. To overcome these challenges, we introduce MELON, a novel multimodal framework designed to predict 12-hour mobility status in the critical care setting. MELON leverages the power of a dual-branch network architecture, combining the strengths of spectrogram-based visual representations and sequential accelerometer statistical features. MELON effectively captures global and fine-grained mobility patterns by integrating a pre-trained image encoder for rich frequency-domain feature extraction and a Mixture-of-Experts encoder for sequence modeling. We trained and evaluated the MELON model on the multimodal dataset of 126 patients recruited from nine Intensive Care Units at the University of Florida Health Shands Hospital main campus in Gainesville, Florida. Experiments showed that MELON outperforms conventional approaches for 12-hour mobility status estimation with an overall area under the receiver operating characteristic curve (AUROC) of 0.82 (95\%, confidence interval 0.78-0.86). Notably, our experiments also revealed that accelerometer data collected from the wrist provides robust predictive performance compared with data from the ankle, suggesting a single-sensor solution that can reduce patient burden and lower deployment costs...

This study introduces the SHAP-integrated convolutional diagnostic network (SICDN), an interpretable feature selection method designed for limited datasets, to address the challenge posed by data privacy regulations that restrict access to medical datasets. The SICDN model was tested on classification tasks using pneumonia and breast cancer datasets, demonstrating over 97% accuracy and surpassing four popular CNN models. We also integrated a historical weighted moving average technique to enhance feature selection. The SICDN shows potential in medical image prediction, with the code available on https://github.com/AIPMLab/SICDN.

Participants: This study employed a combination of Vector Autoregression (VAR) model and Graph Neural Networks (GNN) to systematically construct dynamic causal inference. Multiple classic classification algorithms were compared, including Random Forest, Logistic Regression, XGBoost, Support Vector Machine (SVM), K-Nearest Neighbor (KNN), Gradient Boosting, and Multi Layer Perceptron (MLP). The SMOTE algorithm was used to undersample a small number of samples and employed Stratified K-fold Cross Validation. Results: This study included a total of 11,789 participants, including 6,334 females (53.73%) and 5,455 males (46.27%), with an average age of 65 years. Introduction of dynamic causal inference features has significantly improved the performance of almost all models. The area under the ROC curve of each model ranged from 0.78 to 0.83, indicating significant difference (P < 0.01). Among all the models, the Gradient Boosting model demonstrated the highest performance and stability. Model explanation and feature importance analysis generated model interpretation that illustrated significant contributors associated with risks of stroke. Conclusions and Relevance: This study proposes a stroke risk prediction method that combines dynamic causal inference with machine learning models, significantly improving prediction accuracy and revealing key health factors that affect stroke. The research results indicate that dynamic causal inference features have important value in predicting stroke risk, especially in capturing the impact of changes in health status over time on stroke risk. By further optimizing the model and introducing more variables, this study provides theoretical basis and practical guidance for future stroke prevention and intervention strategies.

Mental health issues among college students have reached critical levels, significantly impacting academic performance and overall wellbeing. Predicting and understanding mental health status among college students is challenging due to three main factors: the necessity for large-scale longitudinal datasets, the prevalence of black-box machine learning models lacking transparency, and the tendency of existing approaches to provide aggregated insights at the population level rather than individualized understanding. To tackle these challenges, this paper presents I-HOPE, the first Interpretable Hierarchical mOdel for Personalized mEntal health prediction. I-HOPE is a two-stage hierarchical model, validated on the College Experience Study, the longest longitudinal mobile sensing dataset. This dataset spans five years and captures data from both pre-pandemic periods and the COVID-19 pandemic. I-HOPE connects raw behavioral features to mental health status through five defined behavioral categories as interaction labels. This approach achieves a prediction accuracy of 91%, significantly surpassing the 60-70% accuracy of baseline methods. In addition, our model distills complex patterns into interpretable and individualized insights, enabling the future development of tailored interventions and improving mental health support. The code is available at https://github.com/roycmeghna/I-HOPE.

In this study, we unveil a new AI model, termed PhyE2E, to discover physical formulas through symbolic regression. PhyE2E simplifies symbolic regression by decomposing it into sub-problems using the second-order derivatives of an oracle neural network, and employs a transformer model to translate data into symbolic formulas in an end-to-end manner. The resulting formulas are refined through Monte-Carlo Tree Search and Genetic Programming. We leverage a large language model to synthesize extensive symbolic expressions resembling real physics, and train the model to recover these formulas directly from data. A comprehensive evaluation reveals that PhyE2E outperforms existing state-of-the-art approaches, delivering superior symbolic accuracy, precision in data fitting, and consistency in physical units. We deployed PhyE2E to five applications in space physics, including the prediction of sunspot numbers, solar rotational angular velocity, emission line contribution functions, near-Earth plasma pressure, and lunar-tide plasma signals. The physical formulas generated by AI demonstrate a high degree of accuracy in fitting the experimental data from satellites and astronomical telescopes. We have successfully upgraded the formula proposed by NASA in 1993 regarding solar activity, and for the first time, provided the explanations for the long cycle of solar activity in an explicit form. We also found that the decay of near-Earth plasma pressure is proportional to r^2 to Earth, where subsequent mathematical derivations are consistent with satellite data from another independent study. Moreover, we found physical formulas that can describe the relationships between emission lines in the extreme ultraviolet spectrum of the Sun, temperatures, electron densities, and magnetic fields. The formula obtained is consistent with the properties that physicists had previously hypothesized it should possess.

Urban region representation is essential for various applications such as urban planning, resource allocation, and policy development. Traditional methods rely on fixed, predefined region boundaries, which fail to capture the dynamic and complex nature of real-world urban areas. In this paper, we propose the Boundary Prompting Urban Region Representation Framework (BPURF), a novel approach that allows for elastic urban region definitions. BPURF comprises two key components: (1) A spatial token dictionary, where urban entities are treated as tokens and integrated into a unified token graph, and (2) a region token set representation model which utilize token aggregation and a multi-channel model to embed token sets corresponding to region boundaries. Additionally, we propose fast token set extraction strategy to enable online token set extraction during training and prompting. This framework enables the definition of urban regions through boundary prompting, supporting varying region boundaries and adapting to different tasks. Extensive experiments demonstrate the effectiveness of BPURF in capturing the complex characteristics of urban regions.

Motivation: Despite recent advancements in semantic representation driven by pre-trained and large-scale language models, addressing long tail challenges in multi-label text classification remains a significant issue. Long tail challenges have persistently posed difficulties in accurately classifying less frequent labels. Current approaches often focus on improving text semantics while neglecting the crucial role of label relationships. Results: This paper introduces LabelCoRank, a novel approach inspired by ranking principles. LabelCoRank leverages label co-occurrence relationships to refine initial label classifications through a dual-stage reranking process. The first stage uses initial classification results to form a preliminary ranking. In the second stage, a label co-occurrence matrix is utilized to rerank the preliminary results, enhancing the accuracy and relevance of the final classifications. By integrating the reranked label representations as additional text features, LabelCoRank effectively mitigates long tail issues in multi-labeltext classification. Experimental evaluations on popular datasets including MAG-CS, PubMed, and AAPD demonstrate the effectiveness and robustness of LabelCoRank.